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Dr. Geetha Kumar

Dean, Professor

Prof. Geetha Kumar currently serves as a Professor at the School of Biotechnology.

Bio

Dr. Geetha Kumar obtained her Ph.D. from the University of Tennessee, Memphis, USA, where she elucidated the structure-function activity of FadL, a bacterial Long Chain Fatty Acid binding protein. Following her Ph.D, Dr.Kumar did her post-doctoral studies under Dr. Neil Nathanson, at the University of Washington, Seattle, USA, on the regulation of Muscarinic Acetylcholine Receptor (mAChR). She was subsequently associated with Ceptyr Inc., a Biotech company where she worked in the High Throughput Screening (HTS) division that focused on developing drugs against Diabetes.

Dr. Kumar is currently a Professor at the School of Biotechnology, Amrita Vishwa Vidyapeetham, where she heads the Microbial Active Genetics lab. that is focused on studying the molecular mechanisms of antibiotic resistance in nosocomial gram-negative pathogens, such as Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter baumannii. Another area of related interest is the use phage biology and active genetics, to target the multidrug resistant (MDR) bacteria in order to revert antibiotic resistant to antibiotic sensitive phenotypes.

The primary research focus of the lab is on combating Antimicrobial Resistance using multiple approaches:

  • Screening Natural Products that can function as anti-quorum sensing agents and elucidating their mechanism of action
  • Isolation, characterization and application of bacteriophages or cocktails of phages for environmental as well as potential clinical use – phage therapy
  • Mutational analysis of the AMR genes of Pseudomonas aeruginosa
  • Phage-mediated gene drive using CRISPR-Cas9 to target the AMR genes of pathogens
  • Understanding Persistence and its role in antimicrobial resistance (AMR)
  • Studying the inter-relationship between virulence and antimicrobial resistance

Education/Training

Institution and Location Degree Year Field of Study
Chinoy College, Mumbai B.Sc. 1982 Microbiology
M.S. University, Baroda M.Sc. 1985 Microbiology
University of Tennessee, Memphis, USA Ph.D. 1992 Biochemistry & Molecular Biology
University of Washington, Seattle, USA Postdoc 1994 Pharmacology

Area of Specialization

Antimicrobial Resistance, Host Pathogen Interactions,  Pharmacology, Drug Discovery, Cancer Biology

Research Support

  • Grant funded in 2018 by The Tata Institute for Genetics and Society (TIGS): Reversal of  antibiotic resistance in ESKAPE
  • Grant funded in the Science Research Scheme (SRS),(2014) Kerala State Council for Science, Technology and Environment, Govt. Of Kerala:  Elucidating the Molecular Mechanisms of Anacardic Acid Mediated Regulation of Matrix Metalloproteinases in Cancer.

Positions and Honours

  • Research Fellow, 1994-1996, MDS Pharma, Seattle, Washington, USA.
  • Research Scientist, 1996 – 2004, Ceptyr Pharmaceuticals Inc., Seattle, Washington, USA.
  • Professor, 2007-Current, Amrita School of Biotechnology
  • Organizing and Program committee member, International Conference on Biotechnology for Innovative Applications (Amrita BioQuest  2013), Amritapuri, India.

Teaching Courses

Publications

Journal Article

Year : 2021

Mathematical modeling of SARS-CoV-2 infection network with cytokine storm, oxidative stress, thrombosis, insulin resistance and nitric oxide pathways.

Authors : Prof. Bipin Nair, Prof. Shyam Diwakar, Dr. Geetha Kumar, Hemalatha Sasidharakurup

Publisher : OMICS A Journal of Integrative Biology

Sasidharakurup H, Kumar G, Nair B, Diwakar S., Mathematical modeling of SARS-CoV-2 infection network with cytokine storm, oxidative stress, thrombosis, insulin resistance and nitric oxide pathways, OMICS A Journal of Integrative Biology, Volume 25, Number 12, 2021 https://doi.org/10.1089/omi.2021.0155.

Year : 2021

A Novel N4-Like Bacteriophage Isolated from a Wastewater Source in South India with Activity against Several Multidrug-Resistant Clinical Pseudomonas aeruginosa Isolates

Authors : Dr. Satheesh Babu T. G., Prof. Bipin Nair, Dr. Geetha Kumar, Menon N.D.; Kumar, M.S.; Bose, S.; Vijayakumar, G.; Baswe, M.; Chatterjee, M.; D’Silva, J.R.; Shetty, K.; Haripriyan, J.; Priyanka Somanath; Kumar, A.;

Publisher : mSphere

Menon N.D., Kumar, M. S., Dr. Satheesh Babu T. G., Bose, S., Vijayakumar, G., Baswe, M., Chatterjee, M., D’Silva, J. R., Shetty, K., Haripriyan, J., Priyanka Somanath, Dr. Bipin G. Nair, Kumar, A., and Dr. Geetha Kumar, “A Novel N4-Like Bacteriophage Isolated from a Wastewater Source in South India with Activity against Several Multidrug-Resistant Clinical Pseudomonas aeruginosa Isolates”, mSphere, vol. 6, no. 1, 2021.

Year : 2021

A Feasibility Trial to Evaluate the Composite Efficacy of Inhaled Nitric Oxide in the Treatment of Covid 19 Pneumonia : Impact on Viral Load and Clinical Outcomes

Authors : Prof. Bipin Nair, Dr. Geetha Kumar, Dr. Aveek Jayant, Dr. Indulekha C. L. Pillai, Merlin Moni; Thushara Madathil; Dipu T. Sathyapalan; Veena Menon; Georg Gutjahr; Fabia Edathadathil; Sureshkumar, Deepthi; Preetha Prasanna; Soumya Jose; Jerome, Roshni; Krishnan, Ajai

Publisher : medRxiv, Cold Spring Harbor Laboratory Press

Merlin Moni, Thushara Madathil, Dipu T. Sathyapalan, Veena Menon, Georg Gutjahr, Fabia Edathadathil, Sureshkumar, D., Preetha Prasanna, Soumya Jose, Jerome, R., Krishnan, A., Indulekha C. L. Pillai, Dr. Geetha Kumar, Dr. Bipin G. Nair, and Aveek Jayant, “A Feasibility Trial to Evaluate the Composite Efficacy of Inhaled Nitric Oxide in the Treatment of Covid 19 Pneumonia : Impact on Viral Load and Clinical Outcomes”, medRxiv, 2021.

Year : 2021

Nuclear factor-κB plays an important role in Tamarixetin-mediated inhibition of matrix metalloproteinase-9 expression.

Authors : Dr. Geetha Kumar, Prof. Bipin Nair, Dr. Damu Sunilkumar, Shaji Sanu K.; G. Drishya; Nanjan Pandurangan

Publisher : Eur J Pharmacol

Shaji Sanu K., G. Drishya, Damu Sunilkumar, Nanjan Pandurangan, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Nuclear factor-κB plays an important role in Tamarixetin-mediated inhibition of matrix metalloproteinase-9 expression.”, European Journal of Pharmacology, vol. 893, p. 173808, 2021.

Year : 2020

Oxyresveratrol drives caspase-independent apoptosis-like cell death in MDA-MB-231 breast cancer cells through the induction of ROS.

Authors : Dr. Geetha Kumar, Dr. Damu Sunilkumar, Drishya G.; Aneesh Chandrasekharan; Sanu K. Shaji; Chinchu Bose; Jennifer Jossart; J. Jefferson P. Perry; Dr. Nandita Mishra; Dr. Geetha Kumar; Dr. Bipin G. Nair

Publisher : Biochemical Pharmacology

Damu Sunilkumar, Drishya G., Aneesh Chandrasekharan, Sanu K. Shaji, Chinchu Bose, Jennifer Jossart, J. Jefferson P. Perry, Dr. Nandita Mishra, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Oxyresveratrol drives caspase-independent apoptosis-like cell death in MDA-MB-231 breast cancer cells through the induction of ROS.”, Biochemical Pharmacology, p. 113724, 2020.

Year : 2020

RECK and TIMP-2 mediate inhibition of MMP-2 and MMP-9 by Annona muricata

Authors : Drishya G., Dr. Jyotsna Nambiar, Sanu K. Shaji, Dr. Muralidharan V., Dr. Damu Sunilkumar, Dr. Chinchu Bose, Dr. Sobha V. Nair, Dr. Sudarslal S., Dr. Geetha Kumar, Prof. Bipin Nair, A. Achuthan, Abishek Kumar, Ashna Alias, Ayesha Sherif, Catherine Joseph, P. Divya, S. Lakshmi

Publisher : Journal of Biosciences

Drishya G., Dr. Jyotsna Nambiar, Sanu K. Shaji, Muralidharan Vanuopadath, Achuthan A., Kumar Abishek, Alias Ashna, Ayesha Sherif, Catherine Joseph, Divya P., Damu Sunilkumar, Chinchu Bose, Dr. Sobha V. Nair, S. Sudarslal, Dr. Geetha Kumar, Lakshmi S., and Dr. Bipin G. Nair, “RECK and TIMP-2 mediate inhibition of MMP-2 and MMP-9 by Annona muricata”, Journal of Biosciences, vol. 45, no. 1, pp. 1-11, 2020.

Year : 2019

Analysis of Microarray Data for Identification of key MicroRNA signatures in Glioblastoma Multiforme

Authors : Prof. Bipin Nair, Dr. Geetha Kumar, Dr. Damu Sunilkumar, S. K. Shaji, V., M. N.

Publisher : Oncology Letters

Sanu K. Shaji, Damu Sunilkumar, Mahalakshmi N. V., Geetha B. Kumar, and Dr. Bipin G. Nair, “Analysis of microarray data for identification of key microRNA signatures in glioblastoma multiforme”, Oncol Lett, vol. 18, no. 2, pp. 1938-1948, 2019.

Year : 2019

Recent Insights into Natural Product inhibitors of Matrix Metalloproteinases

Authors : Prof. Bipin Nair, Dr. Geetha Kumar, J. Perry, J. P., and Martin, D. B. C.

Publisher : Med. Chem. Commun

Dr. Geetha Kumar, Dr. Bipin G. Nair, J. Perry, J. P., and Martin, D. B. C., “Recent insights into natural product inhibitors of matrix metalloproteinases”, Med. Chem. Commun., vol. 10, pp. 2024-2037, 2019

Year : 2018

(I-3,II-3)-Biacacetin-mediated Cell Death involves Mitochondria

Authors : Prof. Bipin Nair, Dr. Geetha Kumar, Jyotsna Nambiar, Gayathri Vijayakumar, G. Drishya, Sanu K Shaji, Nanjan Pandurangan, Geetha B. Kumar

Publisher : Molecular and cellular biochemistry

Jyotsna Nambiar, Gayathri Vijayakumar, G. Drishya, Sanu K Shaji, Nanjan Pandurangan, Geetha B. Kumar, and Dr. Bipin G. Nair, “(I-3,II-3)-Biacacetin-mediated cell death involves mitochondria.”, Molecular and cellular biochemistry, 2018

Year : 2018

Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa.

Authors : Dr. Jayalekshmi H., Dr. Muralidharan V., Dr. Geetha Kumar, Dr. Sudarslal S., Omanakuttan, Athira; Menon, Nitasha D; Nair, Sudarslal Sadasivan; Corriden, Ross; Nair, Bipin G; Nizet, Victor; Kumar, Geetha B

Publisher : Scientific reports

Jayalekshmi H., Omanakuttan, A., Menon, N. D., Muralidharan Vanuopadath, Nair, S. Sadasivan, Corriden, R., Nair, B. G., Nizet, V., and Kumar, G. B., “Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa.”, Sci Rep, vol. 8, no. 1, p. 3437, 2018.

Year : 2017

Coconut Shell Derived Bioactive Compound Oxyresveratrol Mediates Regulation Of Matrix Metalloproteinase 9

Authors : Prof. Bipin Nair, Dr. Chinchu Bose, Dr. Geetha Kumar, Dr. Damu Sunilkumar, Sanu K Shaji, Nanjan Pandurangan, Asoke Banerji

Publisher : International Journal of Pharma and Bio Sciences

Damu Sunilkumar, Chinchu Bose, Sanu K Shaji, Nanjan Pandurangan, Geetha B Kumar, Asoke Banerji, and Dr. Bipin G. Nair, “Coconut Shell Derived Bioactive Compound Oxyresveratrol Mediates Regulation Of Matrix Metalloproteinase 9”, International Journal of Pharma and Bio Sciences, vol. 8, no. 1, pp. 202 – 210, 2017.

Year : 2016

Anacardic acid inhibits gelatinases through the regulation of Spry2, MMP-14, EMMPRIN and RECK.

Authors : Dr. Jyotsna Nambiar, Dr. Chinchu Bose, Meera Venugopal, Dr. Geetha Kumar, Asoke; Patel, Tarun B.; Nair, Bipin G .

Publisher : Experimental Cell Research.

J. Nambiar, Bose, C., Venugopal, M., Banerji, A., Patel, T. B., Dr. Geetha Kumar, and Nair, B. G., “Anacardic acid inhibits gelatinases through the regulation of Spry2, MMP-14, EMMPRIN and RECK.”, Experimental Cell Research, vol. 349, no. 1, pp. 139-151, 2016.

Year : 2016

Nitric Oxide and ERK Mediates Regulation of Cellular Processes by Ecdysterone

Authors : Prof. Bipin Nair, Dr. Geetha Kumar, A. Omanakuttan, Chinchu Bose, N., P., G. B. Kumar, A. Banerji

Publisher : Experimental Cell Research .

A. Omanakuttan, Chinchu Bose, N., P., G. B. Kumar, A. Banerji, and Dr. Bipin G. Nair, “Nitric Oxide and ERK mediates regulation of cellular processes by Ecdysterone”, Experimental Cell Research, vol. 346, no. 2, pp. 167-175, 2016.

Year : 2016

Anacardic Acid Inhibits Gelatinases through the Regulation of Spry2, MMP-14, EMMPRIN and RECK

Authors : Prof. Bipin Nair, Dr. Jyotsna Nambiar, Dr. Chinchu Bose, Meera Venugopal, Late Dr. Asoke Banerji (Memorial Page), Dr. Geetha Kumar, T. B. Patel

Publisher : Experimental Cell Research

Dr. Jyotsna Nambiar, Chinchu Bose, Meera Venugopal, Dr. Asoke Banerji, T. B. Patel, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Anacardic acid inhibits gelatinases through the regulation of Spry2, MMP-14, EMMPRIN and RECK”, Experimental Cell Research, vol. 349, pp. 139-151, 2016

Year : 2016

Clove Bud Oil Reduces Kynurenine and Inhibits pqs A Gene Expression in P. Aeruginosa

Authors : Prof. Bipin Nair, Dr. Jayalekshmi H., Dr. Geetha Kumar, A. Omanakuttan, N. Pandurangan, V. S. Vargis, M. Maneesh

Publisher : Applied microbiology and biotechnology

Jayalekshmi H., A. Omanakuttan, N. Pandurangan, V. S. Vargis, M. Maneesh, Dr. Bipin G. Nair, and Geetha B. Kumar, “Clove Bud Oil Reduces Kynurenine and Inhibits pqs A Gene Expression in P. Aeruginosa”, Applied microbiology and biotechnology, vol. 100, no. 8, pp. 3681-3692, 2016

Year : 2016

Combinatorial Effect of D-amino Acids and Tetracycline against Pseudomonas Aeruginosa Biofilm

Authors : Prof. Bipin Nair, Dr. Geetha Kumar, H. Jayalekshmi, Norin Mary G Victus, R. Anoop, T. M. Sarath, Sajin Sali, C. .Harikrishnan, N. Kaushik, Geetha B Kumar

Publisher : International Journal of Pharmacy and Pharmaceutical Sciences

Jayalekshmi H., Norin Mary G Victus, R. Anoop, T. M. Sarath, Sajin Sali, C. .Harikrishnan, N. Kaushik, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Combinatorial effect of d-amino acids and tetracycline against pseudomonas aeruginosa biofilm”, International Journal of Pharmacy and Pharmaceutical Sciences, vol. 8, no. 11, pp. 216-220., 2016.

Year : 2016

Discovery of Arjunolic Acid as a Novel Non-zinc Binding Carbonic Anhydrase II Inhibitor

Authors : Prof. Bipin Nair, Late Dr. Asoke Banerji (Memorial Page), Dr. Geetha Kumar, S. Kalyanavenkataraman, Pandurangan Nanjan, Dr. Asoke Banerji

Publisher : Bioorganic chemistry

S. Kalyanavenkataraman, Pandurangan Nanjan, Dr. Asoke Banerji, Dr. Bipin G. Nair, and Geetha B Kumar, “Discovery of arjunolic acid as a novel non-zinc binding carbonic anhydrase II inhibitor”, Bioorganic chemistry, vol. 66, pp. 72–79, 2016

Year : 2016

Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity.

Authors : Dr. Geetha Kumar, Hollands, Andrew; Corriden, Ross; Gysler, Gabriela; Dahesh, Samira; Olson, Joshua; Raza Ali, Syed; Kunkel, Maya T; Lin, Ann E; Forli, Stefano; Newton, Alexandra C; Dr. Geetha Kumar; Nair, Bipin G; Perry, J Jefferson P; Nizet, Victor

Publisher : Journal of Biological Chemistry

A. Hollands, Corriden, R., Gysler, G., Dahesh, S., Olson, J., Ali, S. Raza, Kunkel, M. T., Lin, A. E., Forli, S., Newton, A. C., Dr. Geetha Kumar, Nair, B. G., J Perry, J. P., and Nizet, V., “Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity.”, Journal of Biological Chemistry, vol. 291, no. 27, pp. 13964-13973, 2016.

Year : 2015

A Novel2-Alkoxy-3, 5-Dihydroxypyridine Mediated Regulation of Gelatinases

Authors : Prof. Bipin Nair, Dr. Jyotsna Nambiar, Dr. Geetha Kumar, Sanjana S. R., Gorantla S. N., Lankalapalli R. S

Publisher : International Journal of Pharma and Bio Sciences

Dr. Jyotsna Nambiar, Dr. Geetha Kumar, Sanjana S. R., Gorantla S. N., Lankalapalli R. S., and Dr. Bipin G. Nair, “A Novel2-Alkoxy-3, 5-Dihydroxypyridine Mediated Regulation of Gelatinases”, International Journal of Pharma and Bio Sciences, vol. 6, pp. 779-788, 2015.

Year : 2012

Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9

Authors : Prof. Bipin Nair, Dr. Jyotsna Nambiar, Dr. Chinchu Bose, Late Dr. Asoke Banerji (Memorial Page), Dr. Geetha Kumar, A. Omanakuttan, Rodney M. Harris, Pandurangan Nanjan, Rebu K. Varghese, , John A. Tainer, J. Jefferson P. Perry

Publisher : Molecular Pharmacology

A. Omanakuttan, Dr. Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Pandurangan Nanjan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Dr. Asoke Banerji, J. Jefferson P. Perry, and Dr. Bipin G. Nair, “Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9”, Molecular Pharmacology, vol. 82, no. 4, pp. 614-622, 2012

Year : 2001

Identification of a basolateral sorting signal for the M3 muscarinic acetylcholine receptor in Madin-Darby canine kidney cells

Authors : Dr. Geetha Kumar, Nadler, Laurie S; Nathanson, Neil M

Publisher : Journal of Biological Chemistry

L. S. Nadler, Dr. Geetha Kumar, and Nathanson, N. M., “Identification of a basolateral sorting signal for the M3 muscarinic acetylcholine receptor in Madin-Darby canine kidney cells”, Journal of Biological Chemistry, vol. 276, pp. 10539–10547, 2001.

Year : 1999

Asymmetric distribution of muscarinic acetylcholine receptors in Madin-Darby canine kidney cells

Authors : Dr. Geetha Kumar, Nadler, Laurie S; Hinds, Thomas R; Migeon, Jacques C; Nathanson, Neil M

Publisher : Am Physiological Soc

L. S. Nadler, Dr. Geetha Kumar, Hinds, T. R., Migeon, J. C., and Nathanson, N. M., “Asymmetric distribution of muscarinic acetylcholine receptors in Madin-Darby canine kidney cells”, American Journal of Physiology-Cell Physiology, vol. 277, pp. C1220–C1228, 1999.

Year : 1993

Bacterial long-chain fatty acid transport. Identification of amino acid residues within the outer membrane protein FadL required for activity.

Authors : Dr. Geetha Kumar, Black, Paul N

Publisher : Journal of Biological Chemistry

Dr. Geetha Kumar and Black, P. N., “Bacterial long-chain fatty acid transport. Identification of amino acid residues within the outer membrane protein FadL required for activity.”, Journal of Biological Chemistry, vol. 268, no. 21, pp. 15469–15476, 1993.

Year : 1991

Linker mutagenesis of a bacterial fatty acid transport protein. Identification of domains with functional importance.

Authors : Dr. Geetha Kumar, Black, PN

Publisher : Journal of Biological Chemistry

Dr. Geetha Kumar and Black, P. N., “Linker mutagenesis of a bacterial fatty acid transport protein. Identification of domains with functional importance.”, Journal of Biological Chemistry, vol. 266, no. 2, pp. 1348–1353, 1991.

Year : 1989

Hemin and cyclic AMP stimulate message-dependent translation in lysates from Friend erythroleukemia cells.

Authors : Dr. Geetha Kumar, V. G. Chinchar, Turner, L. A

Publisher : Experimental hematology

V. G. Chinchar, Turner, L. A., and Dr. Geetha Kumar, “Hemin and cyclic AMP stimulate message-dependent translation in lysates from Friend erythroleukemia cells.”, Experimental hematology, vol. 17, pp. 405–410, 1989.

Conference Paper

Year : 2015

Ecdysterone Mediates Wound Healing in a Nitric Oxide Dependent Manner in 3T3L1 Fibroblasts.

Authors : Prof. Bipin Nair, Dr. Geetha Kumar, A. Omanakuttan, Dr. Geetha Kumar

Publisher : The XXXIX All India Cell Biology Conference

A. Omanakuttan, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Ecdysterone Mediates Wound Healing in a Nitric Oxide Dependent Manner in 3T3L1 Fibroblasts.”, in The XXXIX All India Cell Biology Conference , 2015.

Conference Proceedings

Year : 2020

Systematic understanding of anti-tumor mechanisms of tamarixetin through network and experimental analyses

Authors : Prof. Bipin Nair, Dr. Geetha Kumar, Sanu K. Shaji, Damu Sunilkumar

Publisher : Rajiv Gandhi Centre for Biotechnology

Sanu K. Shaji, Damu Sunilkumar, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Systematic understanding of anti-tumor mechanisms of tamarixetin through network and experimental analyses”, 39th Annual Conference of Indian Association for Cancer Research (IACR-2020): “Leading the Fight against Cancer”, Rajiv Gandhi Centre for Biotechnology (RGCB), Trivandrum, Kerala, India, February 5-7. 2020.

Year : 2020

Systematic Understanding of Anti-tumor Mechanisms of Tamarixetin through network and Experimental Analyses

Authors : Dr. Nandita Mishra, Prof. Bipin Nair, Dr. Geetha Kumar, , Dr. Damu Sunilkumar, Anupama Binoy; Divya Nedungadi

Publisher : 39th Annual Conference of Indian Association for Cancer Research (IACR-2020): “Leading the Fight against Cancer”, Rajiv Gandhi Centre for Biotechnology (RGCB), Trivandrum

Sanu K. Shaji, Damu Sunilkumar, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Systematic understanding of anti-tumor mechanisms of tamarixetin through network and experimental analyses”, 39th Annual Conference of Indian Association for Cancer Research (IACR-2020): “Leading the Fight against Cancer”, Rajiv Gandhi Centre for Biotechnology (RGCB), Trivandrum, Kerala, India, February 5-7. 2020.

Year : 2020

Role of AIF in Plumbagin induced Paraptosis-A caspase independent cell death in MDA-MB-231 cancer cells

Authors : Dr. Geetha Kumar, Prof. Bipin Nair, Dr. Nandita Mishra, , Anupama, Divya Nedungadi, Dr. Damu Sunilkumar, Sanu K Shaji;

Publisher : 39th Annual Conference of Indian Association for Cancer Research (IACR-2020): “Leading the Fight against Cancer”, Rajiv Gandhi Centre for Biotechnology (RGCB), Trivandrum, Kerala, India

Anupama Binoy, Divya Nedungadi, Damu Sunilkumar, Dr. Bipin G. Nair, and Dr. Nandita Mishra, “Role of AIF in Plumbagin induced Paraptosis-A caspase independent cell death in MDA-MB-231 cancer cells”, 39th Annual Conference of Indian Association for Cancer Research (IACR-2020): “Leading the Fight against Cancer”, Rajiv Gandhi Centre for Biotechnology (RGCB), Trivandrum, Kerala, India, February 5-7. 2020.

Year : 2017

MicroRNA-491 Functions to Down Regulate both Matrix Metalloproteinase-9 and Epidermal growth factor receptor expression and Inhibit Cell Migration in MDA-MB-231 Triple Negative Breast Cancer Cells (Poster)

Authors : Prof. Bipin Nair, Dr. Geetha Kumar, Drishya G., Dr. Damu Sunilkumar, Sanu K Shaji, Dr. Geetha Kumar

Publisher : 27th Swadeshi Science Congress

Sanu K Shaji, Damu Sunilkumar, Drishya G., Dr. Geetha Kumar, and Dr. Bipin G. Nair, “MicroRNA-491 functions to down regulate both matrix metalloproteinase-9 and epidermal growth factor receptor expression and inhibit cell migration in MDA-MB-231 triple negative breast cancer cells (Poster)”, 27th Swadeshi Science Congress. Amritapuri, 2017.

Patents

Year : 2012

Key pad for Medical Devices

Authors : Prof. Bipin Nair, Dr. Geetha Kumar, Eckherd Schaefer; Dr. Geetha Kumar

Publisher : The Patent Office, Government of India_ Certificate of Registration of Design

E. Schaefer, Dr. Bipin G. Nair, and Dr. Geetha Kumar, “Key pad for Medical Devices”, 2012.

Teaching
  • BIO400 / Cell Biology & Stem Cell Biology / 3 Credits /M.Sc. Biotechnology/M.Sc. Microbiology Semester 1
  • Cancer Biology / 3 Credits /M.Sc. Biotechnology/M.Sc. Microbiology
  • Advanced Pharmaceutical Biology / 3 Credits /M.Sc. Biotechnology/M.Sc. Microbiology
  • Advanced Discovery Biology / 3 Credits /M.Sc. Biotechnology/M.Sc. Microbiology
  • Research Methodology / 3 Credits /M.Sc. Biotechnology/M.Sc. Microbiology
Patents
Year Title
2012 Key pad for Medical Devices, Design No. 244105, The Patent Office, Government of India_ Certificate of Registration of Design, 2012.
Projects

Research Projects

Sl. No. Name of the Project Name of the Funding Agency Status On-going / Completed Project Grant / Assistance (Rs.) Duration of the Project Start Year
1. Insulin Pump DST Completed 4 crores 6 Years 2010
2. Wound Healing BMS Completed 30 Lakhs 4 Years 2012
3. Role of MMPs in Cancer Amrita Vishwa Vidyapeetham Completed 2 crores 4 Years 2012
4. Anacardic Acid and its derivatives as novel template for cancer therapy KSCSTE Completed 30 Lakhs 3 Years 2014
5. Reversal of antibiotic resistance in ESKAPE pathogens such as Pseudomonas aeruginosa TIGS On-going 3.6 crores 2 Years 2018
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