Back close

Dr. Geetha Kumar

Dean & HoS, School of Physical Sciences, Amritapuri | Professor, School of Biotechnology, Amritapuri

Qualification: Ph.D
gkumar@am.amrita.edu
Curriculum Vitae
Orcid Profile
Research Gate Profile
Scopus Author ID

Bio

Dr Geetha Kumar obtained her Ph.D. from the University of Tennessee, Memphis, USA, where she elucidated the structure-function activity of FadL, a bacterial Long Chain Fatty Acid binding protein. Following her Ph.D., Dr Kumar did her post-doctoral studies under Dr Neil Nathanson, at the University of Washington, Seattle, USA, on the regulation of Muscarinic Acetylcholine Receptor (mAChR). She was subsequently associated with Ceptyr Inc., a Biotech company where she worked in the High Throughput Screening (HTS) division, that focused on developing drugs against Diabetes.
Dr. Kumar is currently Dean, School of Physical Sciences and Professor, at the School of Biotechnology, Amrita Vishwa Vidyapeetham, where she heads the Antimicrobial Research (AMR) laboratory, that is focused on studying the molecular mechanisms of antibiotic resistance in nosocomial gram-negative pathogens, such as Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter baumannii as well as Candida species. The primary research focus of the lab is on combating Antimicrobial Resistance using multiple approaches:

  • Screening Natural Products that can function as anti-quorum sensing agents and elucidating their mechanism of action
  • Isolation and characterization and of novel lytic bacteriophages against ESKAPE pathogens as well as identification and formulation of phage cocktails for environmental as well as clinical applications – Phage Therapy
  • Understanding Persistence and its role in antimicrobial resistance (AMR)
  • Studying the inter-relationship between virulence and antimicrobial resistance
  • Host directed therapies
  • Surveillance studies to understand and predict emerging patterns of resistance using AI/ML
  • Design and development of early diagnostics
Publications

Journal Article

Year : 2025

Targeting SUMOylation with Anacardic Acid Derivatives: Novel Insights into EGF Pathway Dysregulation in Cancer Using an In Silico Approach

Cite this Research Publication : Sandhya Padmakumar, Boinapalli Gopichand, Anu R. Melge, Aravind Madhavan, Pradeesh Babu, Bipin G. Nair, J. Jefferson P. Perry, Geetha B. Kumar, Targeting SUMOylation with Anacardic Acid Derivatives: Novel Insights into EGF Pathway Dysregulation in Cancer Using an In Silico Approach, ACS Omega, American Chemical Society (ACS), 2025, https://doi.org/10.1021/acsomega.5c06377

Publisher : American Chemical Society (ACS)

Year : 2025

Novel bacteriophages effectively target multidrug-resistant clinical isolates of Klebsiella pneumoniae

Cite this Research Publication : Malavika Binitha Hari, A. L. Sreelekshmi, Pradeesh Babu, Abhijith Pulimoottil Jaykumar, Sivaraj Barath, Sharayu Magar, Sutharsan Govindarajan, John Bernet Johnson, Anil Kumar, Jayalekshmi Haripriyan, Victor Nizet, Jason Gill, Lindsey Camara, Dwayne R. Roach, Bipin G. Nair, Geetha B. Kumar, Novel bacteriophages effectively target multidrug-resistant clinical isolates of Klebsiella pneumoniae, European Journal of Clinical Microbiology & Infectious Diseases, Springer Science and Business Media LLC, 2025, https://doi.org/10.1007/s10096-025-05300-8

Publisher : Springer Science and Business Media LLC

Year : 2025

In Vitro Assessment of Boswellia serrata Incorporated N95 Mask Layers ‐Specific Efficacy Comparison.

Cite this Research Publication : Aiswarya K. Raj, Raichal B. George, Geetha B. Kumar, Jayalekshmi Haripriyan, Kamalam S. Rajni, In Vitro Assessment of Boswellia serrata Incorporated N95 Mask Layers ‐Specific Efficacy Comparison., Global Challenges, Wiley, 2025, https://doi.org/10.1002/gch2.202500328

Publisher : Wiley

Year : 2025

Rv1899c, an HDAC1–ZBTB25-Interacting Protein of Mycobacterium tuberculosis, Promotes Stress Resistance and Immune Evasion in Infected Macrophages

Cite this Research Publication : Arjun M. Menon, Boinapalli Gopichand, Shwetha Susan Thomas, Kuniyil Abhinand, Bipin G. Nair, Geetha B. Kumar, Pradeesh Babu, KB Arun, Lekshmi K. Edison, Aravind Madhavan, Rv1899c, an HDAC1–ZBTB25-Interacting Protein of Mycobacterium tuberculosis, Promotes Stress Resistance and Immune Evasion in Infected Macrophages, International Journal of Molecular Sciences, MDPI AG, 2025, https://doi.org/10.3390/ijms262210872

Publisher : MDPI AG

Year : 2025

Synthesis and Evaluation of Novel 2-((1H-1,2,4-triazol-5-yl)thio)-N-benzylidene-N-phenylacetohydrazide as Potential Antimicrobial Agents

Cite this Research Publication : Athul S., Bhuvaneshwari S. V., Avani Anu G., Parvathi Mohanan P. C., Anu R. Melge, Aravind Madhavan, Bipin G. Nair, Geetha Kumar, Vipin A. Nair, Pradeesh Babu, Synthesis and Evaluation of Novel 2-((1H-1,2,4-triazol-5-yl)thio)-N-benzylidene-N-phenylacetohydrazide as Potential Antimicrobial Agents, International Journal of Molecular Sciences, MDPI AG, 2025, https://doi.org/10.3390/ijms262412078

Publisher : MDPI AG

Year : 2025

Pathogen-induced hijacking of host SUMOylation: from molecular mechanisms and prospects for therapeutic modulation

Cite this Research Publication : Sandhya Padmakumar, Aravind Madhavan, Bipin G. Nair, Geetha B. Kumar, Pathogen-induced hijacking of host SUMOylation: from molecular mechanisms and prospects for therapeutic modulation, Frontiers in Immunology, Frontiers Media SA, 2025, https://doi.org/10.3389/fimmu.2025.1686880

Publisher : Frontiers Media SA

Year : 2025

Klebsiella pneumoniae: Host Interactions, Virulence Mechanisms, and Novel Therapeutic Strategies

Cite this Research Publication : Abhinand Kuniyil, Arjun M. Menon, Shwetha Susan Thomas, Avandika B. Anil, Parvathi Mohanan PC, Arun KB, Lekshmi K. Edison, Pradeesh Babu, Geetha B. Kumar, Bipin G. Nair, Aravind Madhavan, Klebsiella pneumoniae: Host Interactions, Virulence Mechanisms, and Novel Therapeutic Strategies, Microbial Pathogenesis, Elsevier BV, 2025, https://doi.org/10.1016/j.micpath.2025.107856

Publisher : Elsevier BV

Year : 2025

Epigenetic Mechanisms Induced by Mycobacterium tuberculosis to Promote Its Survival in the Host

Cite this Research Publication : Thomas, Shwetha Susan, Kuniyil Abhinand, Arjun M. Menon, Bipin G. Nair, Geetha B. Kumar, K. B. Arun, Lekshmi K. Edison, and Aravind Madhavan. "Epigenetic Mechanisms Induced by Mycobacterium tuberculosis to Promote Its Survival in the Host." International Journal of Molecular Sciences 25, no. 21 (2024): 11801.

Year : 2025

Essential Oils Modulate Virulence Phenotypes in a Multidrug-Resistant Pyomelanogenic Pseudomonas Aeruginosa Clinical Isolate

Cite this Research Publication : Haripriyan, Jayalekshmi, Christy Rose Binu, Nitasha D. Menon, Muralidharan Vanuopadath, Malavika B. Hari, N. Namitha, Kesiya Binoy et al. "Essential oils modulate virulence phenotypes in a multidrug-resistant pyomelanogenic Pseudomonas aeruginosa clinical isolate." Scientific Reports 15, no. 1 (2025): 3738.

Year : 2024

Targeted deletion of Pf prophages from diverse Pseudomonas aeruginosa isolates has differential impacts on quorum sensing and virulence traits

Cite this Research Publication : Amelia K. Schmidt, Caleb M. Schwartzkopf, Julie D. Pourtois, Elizabeth B. Burgener, Dominick R. Faith, Alex Joyce, Tyrza Lamma, Geetha Kumar, Paul L. Bollyky, Patrick R. Secor, Targeted deletion of Pf prophages from diverse Pseudomonas aeruginos isolates has differential impacts on quorum sensing and virulence traits, Journal of Bacteriology, American Society for Microbiology, 2024, https://doi.org/10.1128/jb.00402-23

Publisher : American Society for Microbiology

Year : 2024

Mitigation of quorum sensing mediated virulence factors of Pseudomonas aeruginosa: the role of Meldrum’s acid activated furan

Cite this Research Publication : Ajmal Sadik, Jithin P. Viswaswar, Ambili Rajamoney, Anjali Rekha, Darsana M. Raj, Deepthi Prakashan, Mydhili Vasudevan, J. S. Visakh, Dhannya Renuka, Sreetha Hely, Sanu Korumadathil Shaji, Prakash R. Chandran, Geetha Kumar, Sobha Vijayan Nair, Jayalekshmi Haripriyan, Mitigation of quorum sensing mediated virulence factors of Pseudomonas aeruginosa: the role of Meldrum’s acid activated furan, Frontiers in Microbiology, Frontiers Media SA, 2024, https://doi.org/10.3389/fmicb.2023.1272240

Publisher : Frontiers Media SA

Year : 2024

Computational exploration of novel antimicrobial modalities targeting fucose-binding lectins and ribosomes in Mycobacterium smegmatis using tRNA-encoded peptides

Cite this Research Publication : Pallavi M. Shanthappa, Renuka Suravajhala, Geetha Kumar, Nidheesh Melethadathil, Computational exploration of novel antimicrobial modalities targeting fucose-binding lectins and ribosomes in Mycobacterium smegmatis using tRNA-encoded peptides, Journal of Biomolecular Structure and Dynamics, Informa UK Limited, 2024, https://doi.org/10.1080/07391102.2024.2335555

Publisher : Informa UK Limited

Year : 2024

Comparative Molecular Profiling of Multidrug-resistant Pseudomonas Aeruginosa Identifies Novel Mutations in Regional Clinical Isolates From South India

Cite this Research Publication : Menon, Nitasha D., Priyanka Somanath, Jennifer Jossart, Gayathri Vijayakumar, Kavya Shetty, Manasi Baswe, Meghna Chatterjee et al. "Comparative molecular profiling of multidrug-resistant Pseudomonas aeruginosa identifies novel mutations in regional clinical isolates from South India." JAC-Antimicrobial Resistance 6, no. 1 (2024): dlae001.

Year : 2024

Independent Component Analysis Reveals 49 Independently Modulated Gene sets Within the Global Transcriptional Regulatory Architecture of Multidrug-resistant Acinetobacter baumannii

Cite this Research Publication : Menon, Nitasha D., Saugat Poudel, Anand V. Sastry, Kevin Rychel, Richard Szubin, Nicholas Dillon, Hannah Tsunemoto et al. "Independent component analysis reveals 49 independently modulated gene sets within the global transcriptional regulatory architecture of multidrug-resistant Acinetobacter baumannii." Msystems 9, no. 2 (2024): e00606-23.

Year : 2023

Man vs Microbes – The Race of the Century

Cite this Research Publication : Ericka Anderson, Bipin Nair, Victor Nizet, Geetha Kumar, Man vs Microbes – The Race of the Century, Journal of Medical Microbiology, Microbiology Society, 2023, https://doi.org/10.1099/jmm.0.001646

Publisher : Microbiology Society

Year : 2023

Prostate cancer in India: Current perspectives and the way forward

Cite this Research Publication : Bhargavi R., Barkha Khilwani, Bhumandeep Kour, Nidhi Shukla, Rajaguru Aradhya, Devendra Sharma, Maneesh Vijayvargiya, Abdul S. Ansari, V. Sugunakar, Praveen Mathur, Ashwani Mishra, Gopalakrishna Ramaswamy, Nripesh Sadasukhi, Jayaraman K. Valadi, Krishna Mohan Medicherla, Geetha Kumar, Rupert C. Ecker, Bhawana Bissa, T. C. Sadasukhi, Renuka Suravajhala, Nandita Mishra, Rune Mathiessen, Pranav Johri, Jyotsna Batra, Bipin Nair, Keshav K. Singh, Prashanth N. Suravajhala, Nirmal Kumar Lohiya, Prostate cancer in India: Current perspectives and the way forward, Journal of Reproductive Healthcare and Medicine, Scientific Scholar, 2023, https://doi.org/10.25259/jrhm_17_2023

Publisher : Scientific Scholar

Year : 2022

In silico based multi-epitope vaccine design against norovirus

Cite this Research Publication : Pallavi M. Shanthappa, Renuka Suravajhala, Prashanth Suravajhala, Geetha Kumar, Nidheesh Melethadathil, In silico based multi-epitope vaccine design against norovirus, Journal of Biomolecular Structure and Dynamics, Informa UK Limited, 2022, https://doi.org/10.1080/07391102.2022.2105400

Publisher : Informa UK Limited

Year : 2022

In silico based multi-epitope vaccine design against norovirus

Cite this Research Publication : Pallavi M. Shanthappa, Renuka Suravajhala, Prashanth Suravajhala, Geetha Kumar, Nidheesh Melethadathil, In silico based multi-epitope vaccine design against norovirus, Journal of Biomolecular Structure and Dynamics, Informa UK Limited, 2022, https://doi.org/10.1080/07391102.2022.2105400

Publisher : Informa UK Limited

Year : 2022

Increased Innate Immune Susceptibility in Hyperpigmented Bacteriophage-Resistant Mutants of Pseudomonas aeruginosa

Cite this Research Publication : Menon, Nitasha D., Samuel Penziner, Elizabeth T. Montaño, Raymond Zurich, David T. Pride, Bipin G. Nair, Geetha B. Kumar, and Victor Nizet. "Increased Innate Immune Susceptibility in Hyperpigmented Bacteriophage-Resistant Mutants of Pseudomonas aeruginosa." Antimicrobial Agents and Chemotherapy (2022): e00239-22

Year : 2022

Systematic Understanding of Anti-tumor Mechanisms of Tamarixetin through network and Experimental Analyses

Cite this Research Publication : Sanu K. Shaji, Damu Sunilkumar, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Systematic understanding of anti-tumor mechanisms of tamarixetin through network and experimental analyses”, 39th Annual Conference of Indian Association for Cancer Research (IACR-2020): “Leading the Fight against Cancer”, Rajiv Gandhi Centre for Biotechnology (RGCB), Trivandrum, Kerala, India, February 5-7. 2020.

Publisher : Scientific reports

Year : 2021

Clinical Efficacy of Inhaled Nitric Oxide in Preventing the Progression of Moderate to Severe COVID-19 and Its Correlation to Viral Clearance-Results of a Pilot Study

Cite this Research Publication : Moni M, Madathil T, Sathyapalan DT, Menon V, Gutjahr G, Edathadathil F, Sureshkumar D, Prasanna P, Jose S, Jerome R, Krishnan A, .. Kumar GB, Nair BG. Clinical Efficacy of Inhaled Nitric Oxide in Preventing the Progression of Moderate to Severe COVID-19 and Its Correlation to Viral Clearance-Results of a Pilot Study. Infectious Microbes & Diseases. 2021, Dec 28.

Publisher : Infectious Microbes & Diseases

Year : 2021

Mathematical Modeling of Severe Acute Respiratory Syndrome Coronavirus 2 Infection Network with Cytokine Storm, Oxidative Stress, Thrombosis, Insulin Resistance, and Nitric Oxide Pathways

Cite this Research Publication : Sasidharakurup H, Kumar G, Nair B, Diwakar S. Mathematical Modeling of Severe Acute Respiratory Syndrome Coronavirus 2 Infection Network with Cytokine Storm, Oxidative Stress, Thrombosis, Insulin Resistance, and Nitric Oxide Pathways. OMICS. 2021 Dec;25(12):770-781. doi: 10.1089/omi.2021.0155. Epub 2021 Nov 22. PMID: 34807729, 2021

Publisher : Mary Ann Liebert, Inc., publishers

Year : 2021

Mathematical modeling of SARS-CoV-2 infection network with cytokine storm, oxidative stress, thrombosis, insulin resistance and nitric oxide pathways.

Cite this Research Publication : Sasidharakurup H, Kumar G, Nair B, Diwakar S., Mathematical modeling of SARS-CoV-2 infection network with cytokine storm, oxidative stress, thrombosis, insulin resistance and nitric oxide pathways, OMICS A Journal of Integrative Biology, Volume 25, Number 12, 2021 https://doi.org/10.1089/omi.2021.0155.

Publisher : International Journal of Integrative Biology

Year : 2021

A Novel N4-Like Bacteriophage Isolated from a Wastewater Source in South India with Activity against Several Multidrug-Resistant Clinical Pseudomonas aeruginosa Isolates

Cite this Research Publication : Menon N.D., Kumar, M. S., Dr. Satheesh Babu T. G., Bose, S., Vijayakumar, G., Baswe, M., Chatterjee, M., D’Silva, J. R., Shetty, K., Haripriyan, J., Priyanka Somanath, Dr. Bipin G. Nair, Kumar, A., and Dr. Geetha Kumar, “A Novel N4-Like Bacteriophage Isolated from a Wastewater Source in South India with Activity against Several Multidrug-Resistant Clinical Pseudomonas aeruginosa Isolates”, mSphere, vol. 6, no. 1, 2021.

Publisher : mSphere

Year : 2021

Nuclear factor-κB plays an important role in Tamarixetin-mediated inhibition of matrix metalloproteinase-9 expression.

Cite this Research Publication : Shaji Sanu K., G. Drishya, Damu Sunilkumar, Nanjan Pandurangan, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Nuclear factor-κB plays an important role in Tamarixetin-mediated inhibition of matrix metalloproteinase-9 expression.”, European Journal of Pharmacology, vol. 893, p. 173808, 2021.

Publisher : European Journal of Pharmacology

Year : 2021

A Feasibility Trial to Evaluate the Composite Efficacy of Inhaled Nitric Oxide in the Treatment of Covid 19 Pneumonia : Impact on Viral Load and Clinical Outcomes

Cite this Research Publication : Merlin Moni, Thushara Madathil, Dipu T. Sathyapalan, Veena Menon, Georg Gutjahr, Fabia Edathadathil, Sureshkumar, D., Preetha Prasanna, Soumya Jose, Jerome, R., Krishnan, A., Indulekha C. L. Pillai, Dr. Geetha Kumar, Dr. Bipin G. Nair, and Aveek Jayant, “A Feasibility Trial to Evaluate the Composite Efficacy of Inhaled Nitric Oxide in the Treatment of Covid 19 Pneumonia : Impact on Viral Load and Clinical Outcomes”, medRxiv, 2021.

Publisher : medRxiv, Cold Spring Harbor Laboratory Press

Year : 2020

Oxyresveratrol Drives Caspase-independent Apoptosis-like Cell Death in MDA-MB-231 Breast Cancer Cells through the Induction of ROS.

Cite this Research Publication : Damu Sunilkumar, Drishya G., Aneesh Chandrasekharan, Sanu K. Shaji, Chinchu Bose, Jennifer Jossart, J. Jefferson P. Perry, Dr. Nandita Mishra, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Oxyresveratrol drives caspase-independent apoptosis-like cell death in MDA-MB-231 breast cancer cells through the induction of ROS.”, Biochemical Pharmacology, p. 113724, 2020.

Publisher : Biochemical Pharmacology

Year : 2020

RECK and TIMP-2 mediate inhibition of MMP-2 and MMP-9 by Annona muricata

Cite this Research Publication : Drishya G., Dr. Jyotsna Nambiar, Sanu K. Shaji, Muralidharan Vanuopadath, Achuthan A., Kumar Abishek, Alias Ashna, Ayesha Sherif, Catherine Joseph, Divya P., Damu Sunilkumar, Chinchu Bose, Dr. Sobha V. Nair, S. Sudarslal, Dr. Geetha Kumar, Lakshmi S., and Dr. Bipin G. Nair, “RECK and TIMP-2 mediate inhibition of MMP-2 and MMP-9 by Annona muricata”, Journal of Biosciences, vol. 45, no. 1, pp. 1-11, 2020.

Publisher : Journal of Biosciences

Year : 2019

Recent Insights into Natural Product inhibitors of Matrix Metalloproteinases

Cite this Research Publication : Dr. Geetha Kumar, Dr. Bipin G. Nair, J. Perry, J. P., and Martin, D. B. C., “Recent insights into natural product inhibitors of matrix metalloproteinases”, Med. Chem. Commun., vol. 10, pp. 2024-2037, 2019

Publisher : Med. Chem. Commun

Year : 2019

Analysis of Microarray Data for Identification of key MicroRNA signatures in Glioblastoma Multiforme

Cite this Research Publication : Sanu K. Shaji, Damu Sunilkumar, Mahalakshmi N. V., Geetha B. Kumar, and Dr. Bipin G. Nair, “Analysis of microarray data for identification of key microRNA signatures in glioblastoma multiforme”, Oncol Lett, vol. 18, no. 2, pp. 1938-1948, 2019.

Publisher : Oncology Letters

Year : 2018

(I-3,II-3)-Biacacetin-mediated Cell Death involves Mitochondria

Cite this Research Publication : Jyotsna Nambiar, Gayathri Vijayakumar, G. Drishya, Sanu K Shaji, Nanjan Pandurangan, Geetha B. Kumar, and Dr. Bipin G. Nair, “(I-3,II-3)-Biacacetin-mediated cell death involves mitochondria.”, Molecular and cellular biochemistry, 2018

Publisher : Molecular and cellular biochemistry

Year : 2018

Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa.

Cite this Research Publication : Jayalekshmi H., Omanakuttan, A., Menon, N. D., Muralidharan Vanuopadath, Nair, S. Sadasivan, Corriden, R., Nair, B. G., Nizet, V., and Kumar, G. B., “Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa.”, Sci Rep, vol. 8, no. 1, p. 3437, 2018.

Publisher : Scientific reports

Year : 2017

Coconut Shell Derived Bioactive Compound Oxyresveratrol Mediates Regulation Of Matrix Metalloproteinase 9

Cite this Research Publication : Damu Sunilkumar, Chinchu Bose, Sanu K Shaji, Nanjan Pandurangan, Geetha B Kumar, Asoke Banerji, and Dr. Bipin G. Nair, “Coconut Shell Derived Bioactive Compound Oxyresveratrol Mediates Regulation Of Matrix Metalloproteinase 9”, International Journal of Pharma and Bio Sciences, vol. 8, no. 1, pp. 202 – 210, 2017.

Publisher : International Journal of Pharma and Bio Sciences

Year : 2016

Nitric Oxide and ERK Mediates Regulation of Cellular Processes by Ecdysterone

Cite this Research Publication : A. Omanakuttan, Chinchu Bose, N., P., G. B. Kumar, A. Banerji, and Dr. Bipin G. Nair, “Nitric Oxide and ERK mediates regulation of cellular processes by Ecdysterone”, Experimental Cell Research, vol. 346, no. 2, pp. 167-175, 2016.

Publisher : Experimental Cell Research .

Year : 2016

Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity.

Cite this Research Publication : A. Hollands, Corriden, R., Gysler, G., Dahesh, S., Olson, J., Ali, S. Raza, Kunkel, M. T., Lin, A. E., Forli, S., Newton, A. C., Dr. Geetha Kumar, Nair, B. G., J Perry, J. P., and Nizet, V., “Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity.”, Journal of Biological Chemistry, vol. 291, no. 27, pp. 13964-13973, 2016.

Publisher : Journal of Biological Chemistry

Year : 2016

Discovery of Arjunolic Acid as a Novel Non-zinc Binding Carbonic Anhydrase II Inhibitor

Cite this Research Publication : S. Kalyanavenkataraman, Pandurangan Nanjan, Dr. Asoke Banerji, Dr. Bipin G. Nair, and Geetha B Kumar, “Discovery of arjunolic acid as a novel non-zinc binding carbonic anhydrase II inhibitor”, Bioorganic chemistry, vol. 66, pp. 72–79, 2016

Publisher : Bioorganic chemistry

Year : 2016

Combinatorial Effect of D-amino Acids and Tetracycline against Pseudomonas Aeruginosa Biofilm

Cite this Research Publication : Jayalekshmi H., Norin Mary G Victus, R. Anoop, T. M. Sarath, Sajin Sali, C. .Harikrishnan, N. Kaushik, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Combinatorial effect of d-amino acids and tetracycline against pseudomonas aeruginosa biofilm”, International Journal of Pharmacy and Pharmaceutical Sciences, vol. 8, no. 11, pp. 216-220., 2016.

Publisher : International Journal of Pharmacy and Pharmaceutical Sciences

Year : 2016

Clove Bud Oil Reduces Kynurenine and Inhibits pqs A Gene Expression in P. Aeruginosa

Cite this Research Publication : Jayalekshmi H., A. Omanakuttan, N. Pandurangan, V. S. Vargis, M. Maneesh, Dr. Bipin G. Nair, and Geetha B. Kumar, “Clove Bud Oil Reduces Kynurenine and Inhibits pqs A Gene Expression in P. Aeruginosa”, Applied microbiology and biotechnology, vol. 100, no. 8, pp. 3681-3692, 2016

Publisher : Applied microbiology and biotechnology

Year : 2016

Anacardic Acid Inhibits Gelatinases through the Regulation of Spry2, MMP-14, EMMPRIN and RECK

Cite this Research Publication : Dr. Jyotsna Nambiar, Chinchu Bose, Meera Venugopal, Dr. Asoke Banerji, T. B. Patel, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Anacardic acid inhibits gelatinases through the regulation of Spry2, MMP-14, EMMPRIN and RECK”, Experimental Cell Research, vol. 349, pp. 139-151, 2016

Publisher : Experimental Cell Research

Year : 2015

A Novel2-Alkoxy-3, 5-Dihydroxypyridine Mediated Regulation of Gelatinases

Cite this Research Publication : Dr. Jyotsna Nambiar, Dr. Geetha Kumar, Sanjana S. R., Gorantla S. N., Lankalapalli R. S., and Dr. Bipin G. Nair, “A Novel2-Alkoxy-3, 5-Dihydroxypyridine Mediated Regulation of Gelatinases”, International Journal of Pharma and Bio Sciences, vol. 6, pp. 779-788, 2015.

Publisher : International Journal of Pharma and Bio Sciences

Year : 2012

Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9

Cite this Research Publication : A. Omanakuttan, Dr. Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Pandurangan Nanjan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Dr. Asoke Banerji, J. Jefferson P. Perry, and Dr. Bipin G. Nair, “Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9”, Molecular Pharmacology, vol. 82, no. 4, pp. 614-622, 2012

Publisher : Molecular Pharmacology

Year : 2001

Identification of a basolateral sorting signal for the M3 muscarinic acetylcholine receptor in Madin-Darby canine kidney cells

Cite this Research Publication : L. S. Nadler, Dr. Geetha Kumar, and Nathanson, N. M., “Identification of a basolateral sorting signal for the M3 muscarinic acetylcholine receptor in Madin-Darby canine kidney cells”, Journal of Biological Chemistry, vol. 276, pp. 10539–10547, 2001.

Publisher : Journal of Biological Chemistry

Year : 1999

Asymmetric distribution of muscarinic acetylcholine receptors in Madin-Darby canine kidney cells

Cite this Research Publication : L. S. Nadler, Dr. Geetha Kumar, Hinds, T. R., Migeon, J. C., and Nathanson, N. M., “Asymmetric distribution of muscarinic acetylcholine receptors in Madin-Darby canine kidney cells”, American Journal of Physiology-Cell Physiology, vol. 277, pp. C1220–C1228, 1999.

Publisher : Am Physiological Soc

Year : 1993

Bacterial long-chain fatty acid transport. Identification of amino acid residues within the outer membrane protein FadL required for activity.

Cite this Research Publication : Dr. Geetha Kumar and Black, P. N., “Bacterial long-chain fatty acid transport. Identification of amino acid residues within the outer membrane protein FadL required for activity.”, Journal of Biological Chemistry, vol. 268, no. 21, pp. 15469–15476, 1993.

Publisher : Journal of Biological Chemistry

Year : 1991

Linker mutagenesis of a bacterial fatty acid transport protein. Identification of domains with functional importance.

Cite this Research Publication : Dr. Geetha Kumar and Black, P. N., “Linker mutagenesis of a bacterial fatty acid transport protein. Identification of domains with functional importance.”, Journal of Biological Chemistry, vol. 266, no. 2, pp. 1348–1353, 1991.

Publisher : Journal of Biological Chemistry

Year : 1989

Hemin and cyclic AMP stimulate message-dependent translation in lysates from Friend erythroleukemia cells.

Cite this Research Publication : V. G. Chinchar, Turner, L. A., and Dr. Geetha Kumar, “Hemin and cyclic AMP stimulate message-dependent translation in lysates from Friend erythroleukemia cells.”, Experimental hematology, vol. 17, pp. 405–410, 1989.

Publisher : Experimental hematology

Conference Proceedings

Year : 2020

Role of AIF in Plumbagin induced Paraptosis-A caspase independent cell death in MDA-MB-231 cancer cells

Cite this Research Publication : Anupama Binoy, Divya Nedungadi, Damu Sunilkumar, Dr. Bipin G. Nair, and Dr. Nandita Mishra, “Role of AIF in Plumbagin induced Paraptosis-A caspase independent cell death in MDA-MB-231 cancer cells”, 39th Annual Conference of Indian Association for Cancer Research (IACR-2020): “Leading the Fight against Cancer”, Rajiv Gandhi Centre for Biotechnology (RGCB), Trivandrum, Kerala, India, February 5-7. 2020.

Publisher : 39th Annual Conference of Indian Association for Cancer Research (IACR-2020): “Leading the Fight against Cancer”, Rajiv Gandhi Centre for Biotechnology (RGCB), Trivandrum, Kerala, India

Year : 2017

MicroRNA-491 Functions to Down Regulate both Matrix Metalloproteinase-9 and Epidermal growth factor receptor expression and Inhibit Cell Migration in MDA-MB-231 Triple Negative Breast Cancer Cells (Poster)

Cite this Research Publication : Sanu K Shaji, Damu Sunilkumar, Drishya G., Dr. Geetha Kumar, and Dr. Bipin G. Nair, “MicroRNA-491 functions to down regulate both matrix metalloproteinase-9 and epidermal growth factor receptor expression and inhibit cell migration in MDA-MB-231 triple negative breast cancer cells (Poster)”, 27th Swadeshi Science Congress. Amritapuri, 2017.

Publisher : 27th Swadeshi Science Congress

Conference Paper

Year : 2015

Ecdysterone Mediates Wound Healing in a Nitric Oxide Dependent Manner in 3T3L1 Fibroblasts.

Cite this Research Publication : A. Omanakuttan, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Ecdysterone Mediates Wound Healing in a Nitric Oxide Dependent Manner in 3T3L1 Fibroblasts.”, in The XXXIX All India Cell Biology Conference , 2015.

Publisher : The XXXIX All India Cell Biology Conference

Patents

Year : 2012

Medical device keypad interface.

Cite this Research Publication : Bipin G Nair, Geetha Kumar, Crystal Eastman, Eckhard Schafer. Medical device keypad interface. US Patent No. 29/420,881, May 14, 2012.

Publisher : US Patent No. 29/420,881, May 14, 2012.

Year : 2012

Key pad for Medical Devices

Cite this Research Publication : E. Schaefer, Dr. Bipin G. Nair, and Dr. Geetha Kumar, “Key pad for Medical Devices”, 2012.

Publisher : The Patent Office, Government of India_ Certificate of Registration of Design

Qualification
Institution and Location Degree Year Field of Study
University of Washington, Seattle, USA Postdoc 1994 Pharmacology
University of Tennessee, Memphis, USA Ph.D. 1992 Biochemistry & Molecular Biology
M.S. University, Baroda M.Sc. 1985 Microbiology
Chinoy College, Mumbai B.Sc. 1982 Microbiology
Experience
Position Held Name of the Institute From To
Dean School of Physical Sciences, Amrita Vishwa Vidyapeetham, Kerala 2021 Present
Professor School of Biotechnology, Amrita Vishwa Vidyapeetham, Kerala 2015 Present
Associate Professor School of Biotechnology, Amrita Vishwa Vidyapeetham, Kerala 2005 2014
Research Scientist Ceptry Inc., USA 1996 2005
Research Scientist Pan Labs 1993 1996
Teaching
Research

Area of Specialization

Antimicrobial Resistance, Application of bacteriophages in clinical as well as environmental settings, Host Pathogen Interactions, Pharmacology, Drug Discovery.

Research Support

  • Grant funded in 2018 by The Tata Institute for Genetics and Society (TIGS): Reversal of  antibiotic resistance in ESKAPE
  • Grant funded in the Science Research Scheme (SRS),(2014) Kerala State Council for Science, Technology and Environment, Govt. Of Kerala:  Elucidating the Molecular Mechanisms of Anacardic Acid Mediated Regulation of Matrix Metalloproteinases in Cancer.
Projects
S. No. Name of the Project Name of the Funding Agency Status
(On-going / Completed)
Project Grant / Assistance Duration of the Project Start Year
1 Development of affordable POT (Point of Testing) devices for monitoring of AMR in the Environment. GAMRIF On-going ₹50 lakhs 1 year 2025–2026
2 Therapeutic Chemicals (TC) – Creation of Centre of Excellence (CoE) on Antimicrobial Resistance (AMR) DST-TDT Sanctioned ₹15.5 crores 5 years 2024–2029
3 Development of nitric oxide releasing multifaceted biomaterial-based approach for infected diabetic wounds STARS On-going ₹59 lakhs 3 years 2023–2026
4 Reversal of antibiotic resistance in ESKAPE pathogens TIGS Completed ₹30 lakhs 2 years 2020–2022
5 Reversal of antibiotic resistance in ESKAPE pathogens such as Pseudomonas aeruginosa TIGS Completed ₹3.6 crores 2 years 2018–2020
6 Anacardic Acid and its derivatives as novel template for cancer therapy KSCSTE Completed ₹30 lakhs 3 years 2014–2017
7 Wound Healing BMS Completed ₹30 lakhs 4 years 2012–2016
8 Role of MMPs in Cancer Amrita University Completed ₹2 crores 4 years 2012–2016
9 Insulin Pump DST Completed ₹4 crores 6 years 2010–2016
Summit

Workshops

S. No. Title of the Talk Name of the Event National / International Organizer Venue Date
1 Disarm and Conquer: Anti-Quorum Sensing Agents as Alternative Strategies to Combat AMR CARPE DIEM – Challenging Antibiotic Resistance: Perspectives on Novel Tools and Diagnostics for Efficient Management International Global AMR R&D Hub, Berlin and Manipal School of Life Sciences, MAHE, Manipal Meitner Hall at Harnack Haus, Berlin 16–17 May 2022
2 AMR under Therapeutic Chemicals program of DST AMR under Therapeutic Chemicals program of DST National Technology Development and Transfer (TDT) Division, Dept. of Science and Technology (DST) Hybrid (Online and IIT Kanpur) 16 May 2023
3 Alternatives to Antibiotics – Research Gaps and Priorities Workshop for Creating Momentum for AMR Mitigation – Role of ASPIC Network National ReAct Asia Pacific and ASPIC (Antibiotic Stewardship and Prevention of Infection in Communities) Clubs 8 Aug 2023
4 Meeting at ICMR on “Phage Therapy in Treating Bacterial Infections” Phage Therapy in Treating Bacterial Infections National ICMR, Delhi Delhi 14 June 2023
5 Resisting Antimicrobial Resistance: Strategies to Combat AMR SPARC III Symposium “Point-of-Care Healthcare Devices” & Pant Workshop Series on Medical Technology & Future Medicine National IIT Kanpur IIT Kanpur 25 Nov 2024
6 Phage Therapy with Particular Emphasis on the Regulatory Landscape and Ethical Considerations 5-Day Intensive Workshop: Harnessing Bacteriophages and One Health Approaches to Combat AMR National JSS Science and Technology University JSS Science and Technology University 18–22 Aug 2025
7 Evaluating the Use of Bacteriophages for Global Health Evaluating the Use of Bacteriophages for Global Health International Park Plaza Wallstreet, Berlin, Germany 9 Apr 2025

Conferences attended

S. No. Title of the Talk / Presentation / Poster Name of the Event National / International Organizer Date
1 Formulation of Bacteriophage Cocktails Against Multidrug-Resistant Clinical Pseudomonas aeruginosa Isolates from South India: Implications in Phage Therapy (Oral Presentation) 6th World Conference on Targeting Phage Therapy International International Society of Microbiota, Paris 1–2 June 2023
2 Klebsiella Specific Jumbo Phages: Isolation, Characterization and Clinical Implications (Poster Presentation) VOM 2023 International Viruses of Microbes & Georgian Association for General and Applied Microbiology (GAGAM), Tbilisi 3–7 July 2023
3 From Anti-Virulence Strategies to Bacteriophages: Resisting Antimicrobial Resistance International Conclave on AMR and the Future of Antibiotics National SRM University – AP together with UK Innovate and AMR Insights (Netherlands) 8–10 Oct 2023
4 Bacteriophages as Biologics: Combating the AMR Crisis 4th International Conference on Bacteriophage Research and Anti-microbial Resistance International University of Madras & Bhabha Atomic Research Centre, Chennai 28–30 Sept 2023
5 Structure-Activity Relationship Study of Anacardic Acid: Implications in Cancer Biology Indian Conference on Bioinformatics 2023 – Inbix’23 National Vellore Institute of Technology (VIT) 24–26 Nov 2023
6 Internal Conference Collaboration Discussion Amrita Research & Innovation Symposium for Excellence (ARISE ’24) National Amrita Vishwa Vidyapeetham 7–10 Jan 2024

Poster presentations

  • Isolation of Pseudomonas aeruginosa bacteriophages AM.P1 and AM.P2 from wastewater and characterization of phage activity against multidrug resistant clinical strains from South India – Authors: Nitasha D. Menon, Gayathri Vijayakumar, Manasi Baswe, Bipin G. Nair, Priyanka Somanath, Geetha B. Kumar – Presented at: 23rd Biennial Evergreen International Phage Meeting; International Conference on Bacteriophage Research and Antimicrobial Resistance (ICBRAMR) – Dates: August 4-9th, 2019; December 12-13th, 2019
  • Isolation and Characterization of Bacteriophages against Clinical Multidrug Resistant Klebsiella pneumoniae from South India – Authors: Nitasha D. Menon, Sudhanand M., Sruthi S., Anjali John, Susanna Thomas, Alan Anil, Akhila S. J., Bipin G. Nair, Priyanka Somanath, Geetha B. Kumar – Presented at: 23rd Biennial Evergreen International Phage Meeting – Date: August 4-9th, 2019
Admissions Apply Now