The overarching goal is to address sanitation issues by adopting a holistic approach that incorporates the principles of one health. This approach aims to foster a comprehensive understanding of the intricate interplay between sanitation and various life sciences disciplines. It encompasses the examination of sanitation challenges through the lens of biology, ecology, and other relevant life sciences, providing insights that can guide effective interventions and solutions. Concurrently, the development of evidence-based sanitation protocols is a key focus. These protocols are grounded in scientific research and aim to establish practical and effective guidelines for addressing sanitation issues. In particular, there is a strong emphasis on creating protocols that facilitate the safe valorization of organic waste, a critical aspect of sustainable sanitation management. These protocols not only help reduce environmental impacts but also contribute to the sustainable management of waste by promoting safe and eco-friendly practices. Therefore, through this integrated approach, we strive to enhance sanitation practices and drive positive change in public health, environmental conservation, and overall sanitation management.