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In vitro assay of theranostic agents and their targeted delivery
In vitro assay of theranostic agents and their targeted delivery

This work is in collaboration with Dr. Sankarprasad Bhuniya, Amrita Center for Industrial Research and Innovation (ACIRI), Amrita University, Coimbatore. His lab synthesizes synthetic derivatives with therapeutic as well as diagnostic. . .

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Mitochondrial dynamics
Mitochondrial dynamics

Mitochondria continually undergo fusion and fission along with motility responding to cellular signaling. Our goal is to systematically evaluate the regulatory switches that govern the dynamics. Although the machineries mediating. . .

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Paraptosis: a non-apoptotic cell death pathway to target cancer
Paraptosis: a non-apoptotic cell death pathway to target cancer

Many cancer cells develop resistance to the apoptotic signals and flourish in the system. We are trying to target these defiant cells by inducing an alternative cell death pathway through. . .

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Center of Excellence in Advanced Materials and Green Technologies
Center of Excellence in Advanced Materials and Green Technologies

The Centre for Materials Research will engage in research and development activities in the broad areas encompassing the individual developments in, or an integration of, advanced materials and green technologies. . .

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MIMIC – A Unique approach to wound healing assays
MIMIC – A Unique approach to wound healing assays

Nowadays researchers are interested in cell patterning and here is a method used for patterning mammalian cells that does not require access to photolithographic capabilities. This work describes a versatile. . .

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Modulation of fibrino(geno)lytic proteases from Russell’s viper venom using natural products and analogs
Modulation of fibrino(geno)lytic proteases from Russell’s viper venom using natural products and analogs

Envenomation incapacitates the snake’s prey by interfering with specific aspects of physiological function such as nerve transmission and hemostasis.  Since the action of venom components is highly specific, many venom. . .

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Characterization of the fibronectin isoforms and its fragments
Characterization of the fibronectin isoforms and its fragments

Characterization of Fibronectin isoforms and proteolytic fragments affecting cell behaviour (cell morphology, migration, proliferation) Factors affecting gelatinase (MMP-2) mediated fragmentation of fibronectin

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Molecular Structural Studies of Complex Natural Products by LCMS and UV Spectrophotometry
Molecular Structural Studies of Complex Natural Products by LCMS and UV Spectrophotometry

After broad separation of tannins as lead complex from the SBT extract , flavonoid glycosides (in the supernatant) were subjected to column chromatography using SiO2 and LH-20. Partially purified fractions. . .

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Robust Features for Speaker Verification
Robust Features for Speaker Verification

The project titled “Robust Features for Speaker Verification” is funded by TCS. Dr. C. Santhosh Kumar, Dr. K. I. Ramachandran are the investigators of the project.

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