Publication Type : Journal Article
Publisher : Molecular Diversity
Source : Molecular Diversity, Volume 15, Number 2, p.341–345 (2011)
Url : https://doi.org/10.1007/s11030-010-9281-2
Campus : Amritapuri
School : School of Arts and Sciences
Department : Chemistry
Year : 2011
Abstract : In this study ultrasound has been utilised for the Fischer glycosylation using free sugars and sulphuric acid immobilized on silica as catalyst. N-acetyl-d-glucosamine, N-acetyl-d-galactosamine, d-glucose, d-galactose, d-mannose, l-fucose, and lactose were glycosylated with propargyl alcohol or 2-azidoethanol affording the corresponding glycosides, with the production of the $alpha$-glycopyranoside as the dominant product. Remarkable acceleration of the glycosylation reactions (15nbsp;min–2nbsp;h compared to several hours) over reported procedures together with good yields were always observed
Cite this Research Publication : Dr. Nasrin Shaikh, Russo, L., Cipolla, L., and Nicotra, F., “Ultrasonic assisted Fischer Glycosylation: Generating Diversity for Glycochemistry”, Molecular Diversity, vol. 15, pp. 341–345, 2011.