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Synthesis of substituted-Δ2-1,2,4-triazolin-5-ones and S-substituted isothiobiureas from 1-aryl/alkyl- 6-phenyl-2-thiobiureas

Publication Type : Journal Article

Publisher : Taylor & Francis

Source : Synthetic Communications, 2001

Url : https://www.tandfonline.com/doi/full/10.1081/SCC-100104074?casa_token=QBjVfh9VHfMAAAAA%3A0Kt5agmuN9lpDwwtpDG3-yfFnUnVrCDZjjbChZLn28AIBJ6GbvEmnqvHmkAWTWiCb9-mPQh7vrdDlcZfMg

Campus : Amritapuri

School : School of Biotechnology

Verified : No

Year : 2001

Abstract : Reaction of 1-aryl/ alkyl-6-phenyl-2-thiobiureas 1 with BnCl and BuI in neutral medium at reflux temperature resulted in the formation of the S-alkylated isothiobiureas 2 and 1,2,4-triazolin-5-one derivatives 3. A convenient route to 2 is also reported.

Cite this Research Publication : M. M. Suni, Vipin A. Nair and C. P. Joshua, "Synthesis of substituted-2-1,2,4-triazolin-5-ones and S-substituted isothiobiureas from 1-aryl/alkyl-6-phenyl-2-thiobiureas", Synthetic Communications, 2001, 31, 1599-1605

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