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Synthesis and anti-oxygenic activities of seabuckthorn flavone-3-ols and analogs

Publication Type : Journal Article

Publisher : Science direct

Source : Bioorganic & Medicinal Chemistry Letters

Url : https://www.sciencedirect.com/science/article/pii/S0960894X11009462?casa_token=tAJY_g6uU6UAAAAA:1_0YkttzL-KFpPQtCvHJ1qSq9ovojDebDw_GezVIacDCCBdd7f5rVA2vxO0iLTKecfVgeO5Mods

Campus : Coimbatore

School : School of Physical Sciences

Department : Department of Sciences

Year : 2011

Abstract : A practical synthesis of polyhydroxy- and regiospecifically methylated flavone-3-ols which are components of commercial ‘seabuckthorn flavone’ has been achieved by modified Algar–Flynn–Oyamada method. Antioxidant activities of seabuckthorn extracts, isolated products and a number of flavone-3-ols have been determined. Structure–activity relationships have been discussed. Amongst the compounds tested, gallic acid, which is also present in seabuckthorn, was found to be the most effective antioxidant and radioprotectant.

Cite this Research Publication : Nanjan Pandurangan, Chinchu Bose, Asoke Banerji. Synthesis and anti-oxygenic activities of seabuckthorn flavone-3-ols and analogs. Bioorganic & Medicinal Chemistry Letters, 2011, 21, 5328-5330. (Impact factor: 2.94)

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