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Scrotal Ulceration during Induction Therapy of Acute Promyelocytic Leukemia with ATRA

Publication Type : Journal Article

Publisher : Wiley

Source : American Journal of Hematology

Url : https://doi.org/10.1002/ajh.20036

Keywords : all-trans-retinoic acid, acute promyelocytic leukemia, scrotal ulceration

Campus : Kochi

School : School of Medicine

Department : Medical Oncology

Year : 2004

Abstract : Abstract all-trans-Retinoic acid (ATRA) has been shown to improve survival in patients with acute promyelocytic leukemia (APML). It is a well-tolerated drug except for the serious side effect of ATRA syndrome. Dryness of the skin, cheilitis, and xerostomia are the common mucocutaneous side effects. Occurrence of scrotal ulceration is very rare. We report a 13-year-old boy who had scrotal ulceration caused by ATRA during the induction therapy of APML. Am. J. Hematol. 75:260–261, 2004. © 2004 Wiley-Liss, Inc.

Cite this Research Publication : Keechilat Pavithran, Rajalakshmi Arjun, Raman Aruna, Mathew Thomas, Scrotal ulceration during induction therapy of acute promyelocytic leukemia with ATRA, American Journal of Hematology, Wiley, 2004, https://doi.org/10.1002/ajh.20036

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