Publication

Abstract : Bhaishajya kalpana-Ayurveda Pharmaceutics has umpteen formulations for different diseases which are challenging. Dementia is a chronic mental disorder, characterized by progressive, usually irreversible global cognitive deficit. The signs and symptoms along with pathogenesis of dementia can be understood in terms of smriti nasha, smriti bhramsha. As the pathogenesis of dementia involves neurodegeneration; the role of Rasayana therapy and the medicinal formulations including rasayana drugs attain greater significance in its management. Among the different dosage forms, Ghrita kalpana has an upper hand in the treatment of dementia. Ghrita has vatapittahara, yogavahi and medhya properties which aids in the treatment of symptoms like smrutinasha etc. The significance of using Ghrita as a media aids in incorporating of lipid soluble active principles which then are rapidly distributed throughout the intra and extra cellular spaces and readily diffuse in to CSF and other body cavities. Drugs given in the form of a Ghee are rapidly absorbed and distributed in the target areas of the body like the nervous system. The present paper is an attempt to analyze the effect of Ghrita and its rasayana activity in the management of dementia.