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Rescue right ventricular outflow tract stenting for refrac tory hypoxic spells

Publication Type : Journal Article

Publisher : Catheterization and Cardiovascular Interventions

Source : Catheter Cardiovasc Interv. 2022 Dec 13. https://doi.org/10.1002/ccd.30522 PMID: 36511421.

Url : https://onlinelibrary.wiley.com/doi/abs/10.1002/ccd.30522

Campus : Kochi

School : School of Medicine

Department : Paediatric Cardiology

Year : 2023

Abstract : Background While right ventricular outflow tract stenting (RVOTS) has become an acceptable alternative to palliative surgery in Tetralogy of Fallot (TOF) and similar physiologies, its utility for relief of refractory hypoxic spells is unclear. Methods Patients who underwent RVOTS for emergency relief of refractory hypoxic spells were identified. Specific modifications to enable expeditious RVOTS included use of stent delivery systems (guiding catheter or long sheath) upfront to minimize catheter exchanges; using coronary wires to cross RVOT initially; stabilizing the catheter with a wire in the aorta while crossing RVOT with a second wire. Results From 2015 to 2022, 11 patients underwent RVOTS for hypoxic spells refractory to medical management. Their median age was 27 days (IQR 8.5–442.5); weight 3.27 kg (2.7–8.96); 9 males. Median pulmonary annulus Z score was −4.13 (IQR−4.85 to −0.86). Thirteen stents with median diameter 5 (4–6.5) mm and length 19 (16–19.75) mm were implanted, fluoroscopy time:13.6 (11–26.3) min; procedure time (60, 30–70 min). All were ventilated. Oxygen saturations improved from 45% (40–60) to 90% (84–92); (p < 0.0001) with no major complications. Postprocedure ventilation was needed for 21 (20–49) hours and 4 required diuretic infusion for pulmonary over-circulation. Four needed re-stenting 13 days to 5 months later. At median follow-up of 7 (4–17) months; 2 died from unrelated causes, 3 underwent surgery (two correction and one aorto-pulmonary shunt) and 6 await surgery. Conclusion RVOTS enables safe, expeditious and effective short-term palliation for refractory hypoxic spells. Specific technical modifications facilitate safety, ease and swiftness.

Cite this Research Publication : Sasikumar N, Mohanty S, Balaji S, Kumar RK, "Rescue right ventricular outflow tract stenting for refrac tory hypoxic spells," Catheterization and Cardiovascular Interventions, 2022 Dec 13. https://doi.org/10.1002/ccd.30522 PMID: 36511421.

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