Publication

Abstract : Wrightia tinctoria was investigated for the preliminary phytochemical analysis andcharacterization by various instrumental techniques. Indole derivatives such as isatin, induribine,tryphanthrine and fatty acids were identified. Methanolic extract of leaf parts of Wrightia tinctoria (WT)have been studied against replication of HCV in Huh 5.2 cells. The 50% effective concentration forinhibition of HCV in RNA subgenomic replicon replication in huh 5-2 cells (luciferase assay) by CWTwas found to be 15 µg/mL. The concentration that reduced the growth of exponentially proliferating Huh5-2 cells by 50% was greater than 50 µg /mL.