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Previous Next Effect of Flecainide on Multifocal Ectopic Purkinje-Related Premature Contractions in an R814W SCN5A Carrier

Publication Type : Journal Article

Source : JACC: Case Reports

Url : https://www.jacc.org/doi/abs/10.1016/j.jaccas.2024.102223

Campus : Kochi

School : School of Medicine

Year : 2024

Abstract : Multifocal ectopic Purkinje-related premature contraction (MEPPC) is an autosomal dominant SCN5A channelopathy characterized by frequent multiform premature ventricular contractions originating from the His-Purkinje system. We present a patient with an MEPPC phenotype whose genetic testing identified a pathogenic SCN5A (HGNC:10593) variant amenable to precision antiarrhythmic therapy with flecainide.

Cite this Research Publication : Hisham Ahamed, Arun Gopi, Effect of Flecainide on Multifocal Ectopic Purkinje-Related Premature Contractions in an R814W SCN5A Carrier, JACC: Case Reports ,2024.

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