Publisher : European Journal of Surgical Oncology
Year : 2019
Abstract : {Objectives: To study the determinants of locoregional control (LRC) on stage I/II oral squamous cell carcinoma (OSCC) classified by AJCC 8th edition. Methods: Retrospective analysis from 296 patients of pT1-2N0 oral OSCC treated with surgery (wide local excision and selective neck dissection). Those receiving adjuvant therapy were excluded. Multivariate analysis was performed for impact of adverse pathological features (APFs) on LRC. Results: In stage I, LRC was impacted by perineural invasion (PNI) (HR 7.72