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Photophysical study on synthesized triazolium ionic liquids and their stabilizing effect on native state of serum albumin

Publication Type : Journal Article

Publisher : Elsevier

Source : Journal of Molecular Liquids

Url : https://doi.org/10.1016/j.molliq.2024.125463

Campus : Coimbatore

School : School of Physical Sciences

Department : Chemistry

Year : 2024

Abstract : Room temperature ionic liquids (RTILs) are utilized as solvents and catalysts in organic reactions, with applications spanning from electrochemistry to the detergent sector. Researchers extensively study imidazolium ILs for photophysical analysis in many applications. There are limited studies on the synthesis of triazolium-based ILs and their subsequent photophysical characterization. 1-Alkyl-1,2,4-triazolium-based ILs are selected for their adjustable physiochemical characteristics, strong stability, and capacity for recovery and multiple uses. Two ILs were developed in this study: 1-pentyl-1,2,4-triazolium trifluoroacetate (1-pent3HTTFA) and 1-hexyl-1,2,4-triazolium trifluoroacetate (1-hex3HTTFA). We evaluated the solvent properties of the synthesized ILs using coumarin as a fluorescent probe. Additionally, we investigated the microemulsification of the ILs by using β-Cyclodextrin as the heterogeneous medium. Experiments were conducted to investigate how two triazolium-based ILs interacted with bovine serum albumin (BSA) and their ability to prevent protein denaturation.

Cite this Research Publication : Susithra Selvam, Saranya Cheriyathennatt, Poornima Ratheesh, Ashfana Ashraf, Anjitha Satheesh, Elango Kandasamy, Photophysical study on synthesized triazolium ionic liquids and their stabilizing effect on native state of serum albumin, Journal of Molecular Liquids, Volume 409,2024, 125463,ISSN 0167-7322, https://doi.org/10.1016/j.molliq.2024.125463.

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