Publication Type : Journal Article
Publisher : SpectrochimicaActa Part A
Source : SpectrochimicaActa Part A, 2013, 107, 108-116
Url : https://pubmed.ncbi.nlm.nih.gov/23416915/
Campus : Mysuru
Department : Chemistry
Year : 2013
Abstract : Four novel mononuclear Pd(II) complexes have been synthesized with the biologically active Schiff base ligands (L1-L4) derived from 3-amino-2-methyl-4(3H)-quinazolinone. The structure of the complexes has been proposed by elemental analysis, molar conductance, IR, (1)H NMR, mass, UV-Vis spectrometric and thermal studies. The investigation of interaction of the complexes with calf thymus DNA (CT-DNA) has been performed with absorption and fluorescence spectroscopic studies. The nuclease activity was done using pUC19 supercoiled DNA by gel-electrophoresis. All the ligands and their Pd(II) complexes have also been screened for their antibacterial activity by discolor diffusion technique.
Cite this Research Publication : K. Shiva Prasad*et al.,“Palladium(II) complexes as biologically potent metallo-drugs: Synthesis, spectral characterization, DNA interaction studies and antibacterial activity” SpectrochimicaActa Part A, 2013, 107, 108-116. DOI:10.1016/j.saa.2013.01.013