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Osteopetrosis: A rare cause of anemia

Publication Type : Journal Article

Publisher : Hematology Reviews

Source : Hematology Reviews, Volume 3, Number 1, p.1-2 (2011)

Url : http://www.scopus.com/inward/record.url?eid=2-s2.0-79955394412&partnerID=40&md5=86f6719e662c60b689c278ae687ad652

Keywords : adult, Albers Schoenberg disease, anamnesis, anemia, article, autosomal dominant disorder, blood analysis, bone marrow biopsy, case report, causal attribution, clinical feature, colonoscopy, differential diagnosis, disease association, endoscopy, fluorosis, gastritis, gastrointestinal biopsy, hemoglobin, hemoglobin blood level, hemorrhoid, human, human tissue, image analysis, loose feces, lower abdominal pain, lumbar spine, male, myelofibrosis, nuclear magnetic resonance imaging, osteofluorosis, osteosclerosis, sclerosis, spastic paresis, spine radiography, weakness

Campus : Kochi

School : School of Medicine

Department : Pathology

Year : 2011

Abstract : Normocytic anaemia is caused either by hypoproliferation of haemopoietic tissue or increased destruction of red cells. Osteope -trosis is a rare cause of anaemia. Infantile osteopetrosis (also called malignant osteopet-rosis) is diagnosed early in life. But it is the adult osteopetrosis (also called benign osteopetrosis) which is diagnosed in late adolescence or adulthood that present as anaemia which is difficult to diagnose and treat. Approximately one half of patients are asymptomatic, and the diagnosis is made incidentally, often in late adolescence because radiologic abnormalities start appearing only in childhood. In other patients, the diagnosis is based on family history. Still other patients might present with osteomyelitis or fractures. We are presenting here an unusual case of osteopetro-sis which was referred to us for the evaluation of anaemia. © S. Sreehari et al., 2011.

Cite this Research Publication : S. Sreehari, Naik, D. R., and Eapen, M., “Osteopetrosis: A rare cause of anemia”, Hematology Reviews, vol. 3, pp. 1-2, 2011.

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