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Non- Enzymatic Glucose Sensor.

Publication Type : Patents

Publisher : US 10 , 330 , 634 B2

Source : Amrita Vishwa Vidyapeetham, Volume US 10 , 330 , 634 B2 , Number 15 / 431 , 801 , India (2019)

Url : https://patentimages.storage.googleapis.com/1d/f5/ad/eff0b23aaca063/US10330634.pdf

Campus : Amritapuri

School : School of Biotechnology, School of Engineering

Department : Sciences

Year : 2019

Abstract : There is a major challenge to attach nanostructures on to the electrode surface while retaining their engineered morphology, high surface area, physiochemical features for promising sensing applications. In this study, we have grown vertically-aligned ZnO nanorods (NRs) on fluorine doped tin oxide (FTO) electrodes and decorated with CuO to achieve high-performance non-enzymatic glucose sensor. This unique CuO-ZnO NRs hybrid provides large surface area and an easy substrate penetrable structure facilitating enhanced electrochemical features towards glucose oxidation. As a result, fabricated electrodes exhibit high sensitivity (2961.7 μA mM−1 cm−2), linear range up to 8.45 mM, low limit of detection (0.40 μM), and short response time (<2 s), along with excellent reproducibility, repeatability, stability, selectivity, and applicability for glucose detection in human serum samples. Circumventing, the outstanding performance originating from CuO modified ZnO NRs acts as an efficient electrocatalyst for glucose detection and as well, provides new prospects to biomolecules detecting device fabrication.

Cite this Research Publication : A non - enzymatic glucose sensor and method for fabricating the sensor are disclosed . The glucose sensor contains at least one non - enzymatic electrode configured to catalyze the electro - oxidation of glucose in preference to other bio molecules . The surface of the electrode comprises Cuo nanoparticles . The sensor shows sensitivity and selectivity exceeding enzyme based devices presently in use

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