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NIR fluorescent organic nanoparticles for photoinduced nitric oxide delivery with self monitoring and real time reporting abilities

Publication Type : Journal Article

Source : Journal of Materials Chemistry B

Url : https://pubs.rsc.org/en/content/articlehtml/2018/tb/c8tb01209a

Campus : Amritapuri

School : School of Physical Sciences

Department : Chemistry

Year : 2018

Abstract : Nitric oxide photodonor (NOD) conjugated perylene tetracarboxylate ester (TPT) based fluorescent organic TPT(NOD)4 nanoparticles (NPs) with aggregation induced NIR emission have shown photoinduced nitric oxide delivery along with a red to green emission transition. Time dependent imaging and dose dependent cytotoxicity studies of these NPs using U87MG cells demonstrate the self monitoring and real time reporting abilities and potential anticancer activity of the system, respectively.

Cite this Research Publication : Krishna Kalyani Behara, Y Rajesh, Amrita Chaudhuri, Moumita Gangopadhyay, Mahitosh Mandal, N. D. Pradeep Singh. NIR fluorescent organic nanoparticles for photoinduced nitric oxide delivery with self-monitoring and real time reporting ability. J. Mater. Chem. B 2018, 6(38), 6042- 6046. [DoI: 10.1039/c8tb01209a]

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