Publication Type : Journal Article
Publisher : Science direct
Campus : Kochi
School : School of Medicine
Department : Medical Oncology
Year : 2005
Abstract :
Background : Neuroendocrine carcinoma of the gallbladder is rare. Its best treatment is not known.
Methods : Two patients underwent surgery earlier: one for suspected cholecystitis and the other for cholelithiasis. Magnetic resonance cholangiopancreatography (MRCP) showed residual lesions in the livers. The two patients underwent revision surgery followed by chemotherapy.
Results : Both patients tolerated the second stage surgery well, which was followed by chemotherapy with paclitaxel, ifosphamide and cisplatin for 6 cycles. They were treated this way for 8 months and 12 months post treatment, respectively.
Conclusions : A proper diagnosis of neuroendocrine carcinoma is made often after surgery. As it is a slow growing tumor and not very chemotherapeutically, sensitive surgery offers the best local control.
Cite this Research Publication : Pavithran K, Prabhash K, Hazarika D, Doval DC. Neuroendocrine carcinoma of gallbladder: report of 2 cases. Hepatobiliary Pancreat Dis Int. 2005 Feb;4(1):144-6