Publication Type : Journal Article
Source : Experimental Biology and Medicine Volume 247 Pages 1330-1334, 2022
Url : https://europepmc.org/article/pmc/pmc9442454
Campus : Coimbatore
School : School of Physical Sciences
Year : 2022
Abstract : COVID-19 is caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). The respiratory syndrome has traumatized the world by infecting and taking the lives of larger population. It emerged in December 2019 in Wuhan, China. 1–3 COVID-19 has been linked to the utmost severe and fatal occurrences in people with pre-existing illness like cancer, hypertension, and diabetes. 4 One of the most prevalent comorbidity conditions in critical COVID-19 patients is diabetes mellitus. 5 Diabetes mellitus is an interlinked metabolic disorder affecting 422 million people worldwide6 and is recognized by significantly elevated blood glucose levels that destructs the blood vessels and nerves. It also causes long-term injury to various parts of the body such as, eyes, brain, immune system, kidney, and heart. 7 COVID-19 and diabetes are linked to chronic and acute inflammation, respectively. COVID-19 can influence clinical progression and outcome of diabetes and vice versa. 8 Patients with diabetes and COVID-19 have a higher mortality rate (7.3%) compared to non-diabetic subjects with a mortality rate of 2.3%. 9
Cite this Research Publication : Prakash Gangadaran, Himabindu Padinjarathil, Shri Hari Subhashri Rajendran, Manasi P Jogalekar, Chae Moon Hong, Baladhandapani Aruchamy, Uma Maheswari Rajendran, Sridharan Gurunagarajan, Anand Krishnan, Prasanna Ramani, Kavimani Subramanian, "Minireview Highlight article", Experimental Biology and Medicine Volume 247 Pages 1330-1334, 2022