Publication

Abstract : Background and Aims: Lactate levels predict outcomes after hepatectomy. We compared metabolic effects of lactated versus lactate free solutions in living donor hepatectomy. Methods: Consecutive right lobe donors (n = 53) were alternatively allotted to lactated Ringer’s solution and normal saline (Group L‑control) or acetated crystalloid (Sterofundin B Braun ® Group S ‑study group) in an observational prospective randomised study. The primary outcome measure was lactate level, and secondary outcomes were base excess, bicarbonate, glucose and chloride intra‑ and post‑operatively. Mann–Whitney and Chi‑square tests were used for analysis. Results: The intraoperative, post‑operative lactate levels and the time for normalisation were comparable. Group L had significantly lower intraoperative bicarbonate levels (mmol/L) at 6 and 8 h (20.0 ± 2.14 vs. 21.3 ± 1.6