Publication Type : Journal Article
Publisher : Bentham Science Publishers
Source : Letters in Organic Chemistry Volume 15 Issue 2 Pages 133-138
Campus : Coimbatore
School : School of Physical Sciences
Department : Department of Sciences
Year : 2018
Abstract : The Knoevenagel reaction is one of the most useful methods for the synthesis of α,β- unsaturated nitriles. We disclose an efficient protocol for the Knoevenagel reaction of aldehydes with malononitrile catalyzed by 1-alkyl-1,2,4-triazolium salts to afford the corresponding products in excellent yields. The important feature of this reaction is the catalyst; 1-alkyl-1,2,4-triazolium salts are recycled and reused. Furthermore, the reaction conditions are environment friendly and do not produce any hazardous waste.
Cite this Research Publication : Elango Kandasamy, Sankaranarayanan Nagarajan, Tanveer M Shaikh, "Knoevenagel reaction catalyzed by a reusable bronsted acid based on 1-Alkyl-1, 2, 4-triazolium tetrafluoroborate", Letters in Organic Chemistry Volume 15 Issue 2 Pages 133-138, 2018