Publication Type : Journal Article
Thematic Areas : Medical Sciences
Publisher : Indian Journal of Nephrology
Source : Indian Journal of Nephrology, Volume 22, Number 4, p.275-279 (2012)
Keywords : adult, article, asymptomatic bacteriuria, azathioprine, cefotaxime, ceftazidime, cyclosporin, daclizumab, device removal, female, follow up, graft rejection, hematuria, human, kidney transplantation, laparoscopy, live donor kidney transplantation, major clinical study, male, methylprednisolone, mycophenolic acid 2 morpholinoethyl ester, polyurethan, postoperative period, prednisolone, prophylaxis, randomization, sulfamethoxazole, trimethoprim, ureter obstruction, ureter stent, ureteroneocystostomy, urinary tract, urinary tract infection
Campus : Kochi
School : School of Medicine
Department : Gastrointestinal Surgery, Nephrology, Urology
Year : 2012
Abstract : {Prophylactic ureteric stenting has been shown to reduce ureteric leaks and collecting system obstruction following renal transplantation and is in widespread use. However, the optimal time for removal of ureteric stents after renal transplantation remains unclear. Aim of this study was to compare the result of early versus late removal of ureteric stents after kidney transplantation of the laparoscopically retrieved live related donor grafts. Eligible patients were live donor kidney transplant recipients with normal urinary tracts. All recipients underwent extravesical Lich-Gregoire ureteroneocystostomy over 4F/160 cm polyurethane double J stents by a uniform technique. They were randomized on seventh postoperative day for early removal of stents on postoperative day 7 (Group I), or for late removal on postoperative day 28 (Group II). The incidence of urinary tract infections, asymptomatic bacteriuria, and urological complications were compared. Between 2007 and 2009, 130 kidney transplants were performed at one centre of which 100 were enrolled for the study, and 50 each were randomized into the two groups. Donor and recipient age, sex, native renal disease, immunosupression, number of rejection episodes, and antirejection therapy were similar in the two groups. The occurrence of symptomatic urinary tract infection during the follow-up period of 6 months was significantly less in the early stent removal group [5 out of 50 (10%) in Group I, vs 50 out of 15 (30%) in Group II
Cite this Research Publication : M. Anil, Appu, T., George, K., Georgy, M., Ginil, K., Indu, K. N., Lakshminarayana, G., Nair, B., Rajesh, R., Dr. Sudhindran S., Unni, V. N., and Sanjeevan, K. V., “Is early removal of prophylactic ureteric stents beneficial in live donor renal transplantation”, Indian Journal of Nephrology, vol. 22, pp. 275-279, 2012.