Publication

Abstract : Objectives –1. To analyse clinical and laboratory profile of patients with Expanded Dengue Syndrome. 2.To classify various Expanded Dengue Syndrome based on system involvement. Materials and methods- This was an ambispective observational study performed in 206 patients who presented with clinical features of Dengue fever and had serological confirmation as per WHO definition criteria. This study was conducted in Department of General Medicine, Amrita Institute of Medical Sciences, Kochi from the year of March 2017 to March 2020.Patients were categorised into Expanded Dengue Syndrome as per The WHO 2012 criteria. History, Clinical examination and relevant investigations were analysed. Results - Out of 206 patients,84 were detected to have Expanded Dengue Syndrome. A significant male predilection was noted (65.5%). Maximum patients were observed in the age group of 31-60 years. Among 84 patients, majority of the patients had gastro hepatic manifestations followed by renal involvement. Others include cardiovascular, neurological, co- infections and haematological. Among the biochemical alterations Hyperferritnemia was observed in 43.8% patients followed by transminitis in 40.4% of the study group. Conclusion - Presence of atypical manifestations should raise suspicion to investigate for Expanded Dengue Syndrome. Early identification and treatment decreases the fatal outcomes associated with some of the manifestations in the spectrum of EDS