Publication

Abstract : Worldwide, cardiovascular diseases and associated morbidity have been on a constant rise for the past few years. However, heart transplantation remains a distant option for many owing to demand-supply issues. A completely bio-engineered heart is still a far vision for the hoping patients. The evolving area of cardiac tissue engineering provides a chance to fabricate bioactive scaffolds which would aid in functioning and supporting the cardiac tissues by mimicking the mechanical, chemical, and biological properties of the native tissue. Numerous fibrous scaffolds have been studied and are currently under study in cardiac tissue engineering. This review overviews the latest developments of the electrospun fibrous scaffold decorated with growth factors/cytokines, bioactive nanoparticles, and conductive fibers in cardiac tissue engineering that will help in the beneficial functioning of the cardiac system.