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Publication Type : Journal Article
Publisher : Clinical Microbiology and Infection
Authors : Dr. Raja Biswas, Anil Kumar; Prabhakaran, Aswin; Sherji, Sanju; Lalitha Biswas; Ramachandran, Arya; Abraham, Mohan;
Source : Clinical Microbiology and Infection (2021)
Campus : Kochi
School : Center for Nanosciences
Center : Nanosciences
Year : 2021
Abstract : A boy in his teens on long-term treatment with mycophenolate mofetil and steroids presented with a nodular swelling on the volar aspect of the right forearm. During the previous 2 months, he had experienced creeping eruptions of the right arm. The patient had never travelled outside India. Physical examination found a tender, well-defined 1 × 1-cm, mobile swelling in the subcutaneous plane with fixing of the skin. Ultrasound scan of the swelling revealed a 1.3 × 0.9 cm hyperechoic lesion suggestive of a live worm ( Fig. 1, and see Supplementary material, video S1). Laboratory investigations showed a normal blood leucocyte count without eosinophilia. The excised cystic lesion on sectioning revealed a white thread-like, live worm in a coiled state (see Supplementary material, videos S2, S3). Scanning electron microscopy of the worm surface showed longitudinal ridges and transverse striations ( Fig. 2A,B) ruling out Dirofilaria immitis. The worm was subjected to multiplex PCR, which identified it as Dirofilaria repens; however, sequencing of the cyclo-oxygenase type 1 gene identified it as Candidatus Dirofilaria hongkongensis.
Cite this Research Publication : Anil Kumar, Prabhakaran, A., Sherji, S., Lalitha Biswas, Ramachandran, A., Abraham, M., and Dr. Raja Biswas, “Dirofilarial adult worms can also dance.”, Clinical Microbiology and Infection, 2021.