Publication Type : Journal Article
Publisher : Materials Today: Proceedings, Volume 26, p.720-723 (2020)
Source : Materials Today: Proceedings, Volume 26, p.720-723 (2020)
Url : https://www.sciencedirect.com/science/article/pii/S2214785320300596
Keywords : Antibacterial property, Block copolymers, Drug delivery, Emulsification, micelle
Campus : Amritapuri
School : School of Arts and Sciences
Department : Chemistry
Year : 2020
Abstract : The self-assembly nature of pluronic triblock copolymers have been exploited by materials scientists in the field of drug delivery. We have used Pluronic P123 block copolymer to load an antibiotic drug Amoxicillin and have analyzed the drug loading efficiency. The amphiphilic nature and micellization of Pluronic P123block copolymer was efficiently utilized and the morphology of drug loaded block copolymer is analyzed in detail and correlated with the loading efficiency. Moreover this study also focuses on the antimicrobial activities of the amoxicillin loaded Pluronic P123block copolymer. It is seen that the micelle serve as excellent payloads for the delivery of the most common drug amoxicillin.
Cite this Research Publication : C. Vincent, M.D, K., Jitha S. Jayan, and Dr. Saritha A., “Determination of drug loading efficiency of nano capsules formed by the O/W emulsification of block copolymer”, Materials Today: Proceedings, vol. 26, pp. 720-723, 2020.