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Publication Type : Journal Article
Thematic Areas : Biotech
Publisher : J. Antibiotics
Source : J. Antibiotics, Issue 53, p.110-113 (2000)
Campus : Amritapuri
School : School of Biotechnology
Center : Cell Biology
Department : biotechnology, Microbiology
Year : 2000
Abstract : Two inhibitors of CD45 tyrosine phosphatase, dihydrocarolic acid (1) and penitricin D (2), were isolated from a fermentation broth of the fungus Aspergillus niger and purified by HSCCC (high speed countercurrent chromatography) followed by HPLC. The structures were determined by NMR. The inhibitory activities of both compounds were specific to tyrosine phosphatases.
Cite this Research Publication : K. A. Alvi, Dr. Bipin G. Nair, J. Rabenstein, G. Davis, and D. B. Baker, “CD45 Tyrosine Phosphatase Inhibitory Components from Aspergillus niger”, J. Antibiotics, no. 53, pp. 110-113, 2000