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Case report of delayed metastasis from thyroid micropapillary carcinoma to the deltoid muscle in a patient with thyroglobulin elevated negative iodine scintigraphy (TENIS)

Publication Type : Journal Article

Publisher : Formosan Journal of Surgery

Source : Formosan Journal of Surgery, 2022; 55:70-4. DOI:10.4103/fjs.fjs_243_21

Url : https://journals.lww.com/fjs/Fulltext/2022/55020/Case_report_of_delayed_metastasis_from_thyroid.8.aspx

Campus : Kochi

School : School of Medicine

Department : General Surgery

Year : 2022

Abstract : Differentiated thyroid cancers are common but distant metastasis to the muscles is rare. We present a case of 64-year-old male who underwent thyroidectomy for a suspicious thyroid lesion. His histopathology was reported as widely invasive follicular carcinoma of the thyroid with a focus of micropapillary carcinoma (MPC). He underwent radioiodine ablation. On follow-up, he had a serial increase in thyroglobulin but a whole-body radioiodine scan failed to detect any lesion. An 18-fluorodeoxyglucose positron emission tomography (PET)-computed tomography scan picked up a lesion in the left deltoid muscle. An intraoperative ultrasound localization was done and the nonpalpable lesion was successfully removed surgically. The deltoid lesion was a delayed metastasis of a thyroid MPC. A rising thyroglobulin level in a patient with negative iodine scintigraphy warrants further evaluation with PET since rare distant metastasis may be present. A surgeon performing intraoperative ultrasound is useful in effectively identifying and removing occult lesions with small incisions.

Cite this Research Publication : Ramachandran R, Pillai AV, Samuel S., "Case report of delayed metastasis from thyroid micropapillary carcinoma to the deltoid muscle in a patient with thyroglobulin elevated negative iodine scintigraphy (TENIS)," Formosan Journal of Surgery, 2022; 55:70-4. DOI:10.4103/fjs.fjs_243_21

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