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Biotransformations with Rhizopus arrhizus: Preparation of the enantiomers of 1-phenylethanol and 1-( fo-, m-and p-methoxyphenyl) ethanols

Publication Type : Journal Article

Thematic Areas : Biotech

Publisher : Elsevier

Source : Tetrahedron: Asymmetry, Elsevier, Volume 6, Number 9, p.2287–2290 (1995)

Url : http://www.sciencedirect.com/science/article/pii/0957416695003048

Campus : Amritapuri

School : School of Biotechnology

Center : Biotechnology, Phytochemistry Labs, Sanitation Biotechnology

Department : biotechnology

Year : 1995

Abstract : The fungus Rhizopus arrhizus has been used for the reduction of acetophenone and its o-, m- and p-methoxy derivatives 1a–d to the corresponding (S)-(−)-alcohols. Their racemic acetates were also hydrolyzed to (R)-(+)-alcohols. The analysis of products revealed that maximum enantioselectivity (78–88 %ee) could be obtained using m-methoxy acetophenone as substrate.

Cite this Research Publication : N. A. Salvi, Patil, P. N., Udupa, S. R., and Banerji, A., “Biotransformations with Rhizopus arrhizus: Preparation of the enantiomers of 1-phenylethanol and 1-( fo-, m-and p-methoxyphenyl) ethanols”, Tetrahedron: Asymmetry, vol. 6, pp. 2287–2290, 1995.

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