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Biosurfactant as an intervention for medical device associated infections

Publication Type : Book Chapter

Publisher : Academic Press

Source : Academic Press (Elsevier), 2022, Chapter 24, Pages 451-465, ISBN: 9780323851466.

Url : https://www.sciencedirect.com/science/article/pii/B9780323851466000073#!

Campus : Kochi

School : School of Biotechnology

Department : biotechnology

Year : 2022

Abstract : Nosocomial infections emerging due to the medical devices represent a notable challenge for healthcare systems and professionals. The majority of these infections are due to biofilm formation on the polymeric surface which is resistant toward eradication and demand for extensive antibiotic treatment, device nonfunctionality, and removal. To counter these infections, efforts are been underway to modify the polymeric surfaces of diverse medical devices as coatings and/or impregnation with molecules having potent antibiofouling and biofilm inhibition properties. These strategies might result in the leaching of these active compounds with potent activity from the device surfaces that prevent initial adhesion and further biofilm formation. This article highlights the role of diverse biosurfactants secreted from various sources as a strategy to reduce microbial adhesion and biofilm inhibition. Biosurfactants with potent antibiofilm and anti-adhesion properties are detailed. In addition, the need for developing medical devices that coated and/ or impregnated with biosurfactants was also specified.

Cite this Research Publication : Prasanth Rathinam, Sherly Antony, Reshmy R, Aravind Madhavan, Parameswaran Binod, Ashok Pandey, Raveendran Sindhu. Biosurfactant as an intervention for medical device associated infections. In book Green Sustainable Process for Chemical and Environmental Engineering and Science. Editors: Inamuddin, Charles Oluwaseun Adetunji and Mohd Imran Ahamed. Green Sustainable Process for Chemical and Environmental Engineering and Science Biomedical Application of Biosurfactant in Medical Sector. Academic Press (Elsevier), 2022, Chapter 24, Pages 451-465, ISBN: 9780323851466. DOI: https://doi.org/10.1016/B978-0-323-85146-6.00007-3

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