Publication Type : Journal Article
Publisher : Thieme
Source : Synthesis, 2011
Url : https://thieme-connect.com/products/ejournals/abstract/10.1055/s-0030-1260187
Campus : Amritapuri
School : School of Biotechnology
Verified : No
Year : 2011
Abstract : The usefulness of (S)-4-isopropyl-1-phenylimidazolidin-2-thione as a chiral auxiliary in stereoselective propionate and acetate aldol reactions is discussed. Further, the enantioselective synthesis of (R)-baclofen by acetate aldol reaction using the chiral auxiliary was demonstrated.
Cite this Research Publication : Gopal L. Khatik, Ravi Khurana, Varun Kumar and Vipin A. Nair, "Asymmetric induction by (S)-4-isopropyl-1-phenylimidazolidin-2-thione in titanium mediated aldol
reactions and its application in enantioselective synthesis of (R)-baclofen", Synthesis, 2011, 43, 3123-3132