Programs
- M. Tech. in Automotive Engineering -
- Fellowship In Interventional Pulmonology and Pulmonary Critical care - Fellowship
Publisher : PLoS ONE
Campus : Kochi
School : School of Medicine
Year : 2013
Abstract : Background:From among a cohort of 65,553 men aged 30-84 in Karunagappally Taluk, Kerala, India, 52 hypopharyngeal cancer cases and 85 laryngeal cancer cases were identified by the Karunagappally Cancer Registry during the period between 1990 and 2009.Methods:We conduct Poisson regression analysis of grouped data, taking into account age and education.Results:This study showed that the incidence rates of cancers of the hypopharynx and the larynx were strongly related to the number of bidis smoked a day (P0.001 for both hypopharyngeal and laryngeal cancers) and duration of bidi smoking (P=0.009; P0.001). Laryngeal cancer risk was significantly increased by bidi smoking (P0.001), cigarette smoking (P=0.013) and regular alcohol use (P=0.005).Conclusion:The present study, the first cohort study to examine the association of hypopharyngeal and laryngeal cancer incidence rates with bidi smoking in South Asia, clearly showed dose-response relationships between those cancer risks and bidi smoking; larger amounts of bidi smoked a day and longer durations of bidi smoking increased the incidence rates of those cancers. Tobacco chewing was found not related to the risk of hypopharynx or larynx cancer. © 2013 Jayalekshmi et al.