Publication Type : Journal Article
Publisher : BMJ Case Reports
Source : BMJ Case Reports, Volume 14, Issue 4, 28 April 2021, Article number e240046
Url : http://www.scopus.com/inward/record.url?eid=2-s2.0-85105082684&partnerID=MN8TOARS
Campus : Kochi
School : School of Medicine
Department : Respiratory Medicine, Rheumatology
Year : 2021
Abstract : Melanoma differentiation-associated protein 5 (MDA5) antibody-positive dermatomyositis (DM) displays unique cutaneous and pathologic features. We describe two cases of myositis-associated rapidly progressive interstitial lung disease (RP-ILD). The patients were two women from Kerala, India. Both patients had anti-MDA5 antibody-positive myositis. Both patients presented with RP-ILD without any clinical features of myositis and succumbed to their illness despite aggressive medical treatment. Anti-MDA5-antibody-positive DM is characterised by amyopathic disease with rapidly progressive and fatal ILD. ©
Cite this Research Publication : Asmita A Mehta, Tisa Paul, Mithun CB, Nithya Haridas, "Anti-MDA5 antibody-positive dermatomyositis with rapidly progressive interstitial lung disease: report of two cases," BMJ Case Reports, Volume 14, Issue 4, 28 April 2021, Article number e240046