Back close

An update on possible alternative therapeutics for future periodontal disease management

Publication Type : Journal

Publisher : Oxford University Press

Source : Journal of Applied Microbiology

Url : https://academic.oup.com/jambio/article/134/1/lxac039/6902079

Campus : Kochi

School : Center for Nanosciences, School of Nanosciences

Center : Nanosciences

Year : 2023

Abstract : Periodontitis is an inflammatory disease caused by microbial infections of the gum. At an advanced stage, periodontitis can even destroy the alveolar bone. Fusobacterium nucleatum, Prevotella intermedia, Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Capnocytophaga gingivalis, and Pr. nigrescens are the major pathogens in periodontitis. Scaling and root planning are used together with local or systemic antibiotics to treat periodontitis. The difficulty in complete eradication of periodontal pathogens frequently leads to the relapse of the disease. As not many new antibiotics are available in the market, many researchers are now focusing on developing alternative strategies against periodontal microbes. This review provides an overview of the possible use of bacteriophages, lysins, honey, plant extracts, metallic salts, nanoparticles, and vaccines as alternative therapeutic agents against periodontal infections. The information provided here could help in designing alternative therapeutics for the treatment of periodontal infections.

Cite this Research Publication : Das, V., Vinod, V., Biswas, L., Kumar, A., Biswas, R. An update on possible alternative therapeutics for future periodontal disease management (2023) Journal of Applied Microbiology, 134, lxac039.

Admissions Apply Now