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An efficient one-pot synthesis of 2-benzylpyrroles and 3-benzylindoles

Publication Type : Journal Article

Source : Applied Organometallic Chemistry, 2011

Url : https://onlinelibrary.wiley.com/doi/full/10.1002/aoc.1759?casa_token=8x3FkhMTuocAAAAA%3AX5pbj1Mq_mDC-s3PJntDAa7nRUNZwvWDFz7QRubU-pao_Mo1ab3Rpd_yFiRYRtEol2UbsaLPjRcC0YCs3A

Campus : Amritapuri

School : School of Biotechnology

Verified : No

Year : 2011

Abstract : One-pot regioselective benzylation of pyrroles and indoles using zirconium tetrachloride is discussed. This has been achieved by in-situ generation of di(1H-pyrrol-1-yl)zirconium(IV) chloride and di(1H-indol-1-yl)zirconium(IV) chloride. It was observed that benzylation reactions of these complexes using n-BuLi occurred at C-2 position for pyrrole and C-3 for indole. Copyright © 2011 John Wiley & Sons, Ltd.

Cite this Research Publication : Ratnesh Sharma, Mangilal Chouhan, Divya Sood and Vipin A. Nair,"An efficient one-pot synthesis of 2-benzylpyrroles and 3-benzylindoles", Applied Organometallic Chemistry 2011, 25, 470-475.

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