Publication

Abstract : In the current era of post genomics, research in discovery of biomarker with respect to the application of principles in nanotechnology and bioinformatics raised opportunities in the field of personalized medicine in which diseases are detected, diagnosed and regular follow up of therapeutic regimen were tailored to each and every individual on the basis of their molecular profile. In Case of predictive medicine the usage of genetic/molecular information play a vital role in predicting the development of disease progression and clinical outcome. In this review, we discuss the recent advancement of tools developed on the principles of bioinformtics to accelerate the biomarker discovery of cancer and the usage of multiplexed nanoparticle probes for profiling the biomarker of cancer. Finally, with respect to future prospectives and further challenges in biomarker discover of Cancer, we correlate the signatures of biomolecules with their clinical outcome. So, the term Bio-Nano-Info is a promise for individualized therapy with respect to molecular diagnosis of cancer and the same principle can also be applied to other human diseases.