Back close
Admissions

Proteasome inhibitors from natural products

School: School of Biotechnology

Project Incharge:Dr. Nandita Mishra
Proteasome inhibitors from natural products

The ubiquitin-proteasome system (UPS) plays an essential role in many cellular processes, including cell cycle progression, proliferation, apoptosis and angiogenesis. Proteasome inhibitors like Bortezomib (Velcade, PS-341), has been successfully used as anticancer drug. Several natural compounds, including the green tea polyphenols, microbial metabolite lactacystin and many triterpenes have been shown to be potent proteasome inhibitors. One of our ongoing project is to screen novel proteasomal inhibitors from natural products that induce cell death in cancer cells.

Related Projects

Development of a Lab-on-a-Chip (LoC) for detection of Glucose, Cholesterol and Kidney Function
Development of a Lab-on-a-Chip (LoC) for detection of Glucose, Cholesterol and Kidney Function
Schiff’s Base Derivative Of Chitosan: A Potential Matrix For Metalloprotein Enrichment
Schiff’s Base Derivative Of Chitosan: A Potential Matrix For Metalloprotein Enrichment
Process Development for Isolation and Characterization of Phytochemicals
Process Development for Isolation and Characterization of Phytochemicals
Development of New Tools to Reverse Antibiotic Resistance in Pathogens Like Pseudomonas Aeruginosa
Development of New Tools to Reverse Antibiotic Resistance in Pathogens Like Pseudomonas Aeruginosa
Isolation,Partial Purification and Characterisation of Bacteriocins from Fermented Foods
Isolation,Partial Purification and Characterisation of Bacteriocins from Fermented Foods
Admissions Apply Now