Back close

Photo switchable Azobenzene Conjugated Matrices for Affinity Chromatography: Synthesis, Characterization and Studies

Start Date: Sunday, Jan 01,2012

End Date: Wednesday, May 30,2012

School: School of Biotechnology

Thematic Area: Biotech

Project Incharge:Dr. Sobha V. Nair
Co-Project Incharge:Reshma T.V., Sruthi.S, Dilip M V, Maya M.L. Prakash Chandran
Photo switchable Azobenzene Conjugated Matrices for Affinity Chromatography: Synthesis, Characterization and Studies

There are reports on derivatives of azobenzene that exhibit light-triggered association of Bovine Serum Albumin. To this end, an azobenzene-triazine conjugate was prepared by reacting Disperse Orange 3 dye with trichlorotrizaine. This intermediate was then conjugated to the biopolymer chitosan by a facile nucleophilic substitution. It was presumed that the interactions between the azobenzene moiety and albumin would lead to the development of new matrices which can bind albumin effectively.

Related Projects

Computational Chemistry & Molecular Docking Studies
Computational Chemistry & Molecular Docking Studies
Glucosamine Conjugated Chitosan Derivatives- Synthesis and Study of Antimicrobial Activity
Glucosamine Conjugated Chitosan Derivatives- Synthesis and Study of Antimicrobial Activity
Chemistry Virtual Labs
Chemistry Virtual Labs
Isolation and Characterization of Primary Tumor Cells
Isolation and Characterization of Primary Tumor Cells
Modulation of fibrino(geno)lytic proteases from Russell’s viper venom using natural products and analogs
Modulation of fibrino(geno)lytic proteases from Russell’s viper venom using natural products and analogs
Admissions Apply Now