Back close

Photo switchable Azobenzene Conjugated Matrices for Affinity Chromatography: Synthesis, Characterization and Studies

Start Date: Sunday, Jan 01,2012

End Date: Wednesday, May 30,2012

School: School of Biotechnology

Thematic Area: Biotech

Project Incharge:Dr. Sobha V. Nair
Co-Project Incharge:Reshma T.V., Sruthi.S, Dilip M V, Maya M.L. Prakash Chandran
Photo switchable Azobenzene Conjugated Matrices for Affinity Chromatography: Synthesis, Characterization and Studies

There are reports on derivatives of azobenzene that exhibit light-triggered association of Bovine Serum Albumin. To this end, an azobenzene-triazine conjugate was prepared by reacting Disperse Orange 3 dye with trichlorotrizaine. This intermediate was then conjugated to the biopolymer chitosan by a facile nucleophilic substitution. It was presumed that the interactions between the azobenzene moiety and albumin would lead to the development of new matrices which can bind albumin effectively.

Related Projects

Cyclooxygenase-2 in Cancer and Inflammatory Diseases
Cyclooxygenase-2 in Cancer and Inflammatory Diseases
Isolation of Carbohydrate Binding Proteins (lectins) from Natural Sources
Isolation of Carbohydrate Binding Proteins (lectins) from Natural Sources
Isolation and identification of endophytes from marine algae
Isolation and identification of endophytes from marine algae
Matrix Binding microbes and bacteriophages to counter infection
Matrix Binding microbes and bacteriophages to counter infection
Mass Spectrometric Characterization of Bioactive Peptides and Proteins
Mass Spectrometric Characterization of Bioactive Peptides and Proteins
Admissions Apply Now