Back close

Photo switchable Azobenzene Conjugated Matrices for Affinity Chromatography: Synthesis, Characterization and Studies

Start Date: Sunday, Jan 01,2012

End Date: Wednesday, May 30,2012

School: School of Biotechnology

Thematic Area: Biotech

Project Incharge:Dr. Sobha V. Nair
Co-Project Incharge:Reshma T.V., Sruthi.S, Dilip M V, Maya M.L. Prakash Chandran
Photo switchable Azobenzene Conjugated Matrices for Affinity Chromatography: Synthesis, Characterization and Studies

There are reports on derivatives of azobenzene that exhibit light-triggered association of Bovine Serum Albumin. To this end, an azobenzene-triazine conjugate was prepared by reacting Disperse Orange 3 dye with trichlorotrizaine. This intermediate was then conjugated to the biopolymer chitosan by a facile nucleophilic substitution. It was presumed that the interactions between the azobenzene moiety and albumin would lead to the development of new matrices which can bind albumin effectively.

Related Projects

Antimicrobial Activity of Aqueous Extracts of Plants Against Multidrug Resistant P.aeruginosa
Antimicrobial Activity of Aqueous Extracts of Plants Against Multidrug Resistant P.aeruginosa
Peptide-Based Anti-Snake Venom Therapy
Peptide-Based Anti-Snake Venom Therapy
Schiff’s Base Derivative Of Chitosan: A Potential Matrix For Metalloprotein Enrichment
Schiff’s Base Derivative Of Chitosan: A Potential Matrix For Metalloprotein Enrichment
Comparison of Anti-microbial Activity of Anti-acne Agents
Comparison of Anti-microbial Activity of Anti-acne Agents
Mass Spectrometry Assisted Identification of Antioxidant Pigments from Stoechospermum polypodioides, a Marine Brown Macro Alga
Mass Spectrometry Assisted Identification of Antioxidant Pigments from Stoechospermum polypodioides, a Marine Brown Macro Alga
Admissions Apply Now