Back close

Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Start Date: Sunday, Mar 01,2009

School: School of Biotechnology

Funded by:Amrita Vishwa Vidyapeetham
Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Divergent oriented synthesis is a strategy which aims to the synthesis of compounds with diverse chemical structures. It is often an alternative to convergent synthesis or linear synthesis. With this intention, the diversity oriented synthesis was developed. In Phytochemistry laboratory our aims is to generate a library of bioactive oxygen heterocyclic compounds by first reacting with a easily available starting material to form set of intermediates, e.g. chalcones, 1,3-diketones.  The next target compounds are generated by suitable transformations of  intermediates, e.g. flavones, flavonols, flavanones, isoflavones and biflavones. This methodology quickly diverges to large numbers of different classes of compounds from simple starting materials. It is also efficient synthesis. The scheme methodology is given below.

diversity-bio-project

Some examples of  compounds synthesised are given below:

  1. chalcones
  2. dihydroflavonols
  3. flavones
  4. flavonol 
  5. isoflavones

Related Projects

Bio Enhancing Property of Cow’s Urine In Combination with Antibiotics and Natural Plant Extracts
Bio Enhancing Property of Cow’s Urine In Combination with Antibiotics and Natural Plant Extracts
Benchtop Nanoscale patterning using soft lithography for the printing of DNA molecules
Benchtop Nanoscale patterning using soft lithography for the printing of DNA molecules
Quorum Sensing and Biofilm Formation in Microbial Pathogenesis
Quorum Sensing and Biofilm Formation in Microbial Pathogenesis
Matrix Binding microbes and bacteriophages to counter infection
Matrix Binding microbes and bacteriophages to counter infection
Organic Bulk Heterojunction Devices for Photovoltaic Solar Cell Applications
Organic Bulk Heterojunction Devices for Photovoltaic Solar Cell Applications
Admissions Apply Now