Start Date: Sunday, Mar 01,2009
School: School of Biotechnology
Divergent oriented synthesis is a strategy which aims to the synthesis of compounds with diverse chemical structures. It is often an alternative to convergent synthesis or linear synthesis. With this intention, the diversity oriented synthesis was developed. In Phytochemistry laboratory our aims is to generate a library of bioactive oxygen heterocyclic compounds by first reacting with a easily available starting material to form set of intermediates, e.g. chalcones, 1,3-diketones. The next target compounds are generated by suitable transformations of intermediates, e.g. flavones, flavonols, flavanones, isoflavones and biflavones. This methodology quickly diverges to large numbers of different classes of compounds from simple starting materials. It is also efficient synthesis. The scheme methodology is given below.
Some examples of compounds synthesised are given below: