Back close

Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Start Date: Sunday, Mar 01,2009

School: School of Biotechnology

Funded by:Amrita Vishwa Vidyapeetham
Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Divergent oriented synthesis is a strategy which aims to the synthesis of compounds with diverse chemical structures. It is often an alternative to convergent synthesis or linear synthesis. With this intention, the diversity oriented synthesis was developed. In Phytochemistry laboratory our aims is to generate a library of bioactive oxygen heterocyclic compounds by first reacting with a easily available starting material to form set of intermediates, e.g. chalcones, 1,3-diketones.  The next target compounds are generated by suitable transformations of  intermediates, e.g. flavones, flavonols, flavanones, isoflavones and biflavones. This methodology quickly diverges to large numbers of different classes of compounds from simple starting materials. It is also efficient synthesis. The scheme methodology is given below.

diversity-bio-project

Some examples of  compounds synthesised are given below:

  1. chalcones
  2. dihydroflavonols
  3. flavones
  4. flavonol 
  5. isoflavones

Related Projects

Design and Validation of Point of Care Disposable Sensor Strips for Diagnosis of Tuberculosis from Urine Samples
Design and Validation of Point of Care Disposable Sensor Strips for Diagnosis of Tuberculosis from Urine Samples
Development of a Lab-on-a-Chip (LoC) for detection of Glucose, Cholesterol and Kidney Function
Development of a Lab-on-a-Chip (LoC) for detection of Glucose, Cholesterol and Kidney Function
Isolation and Characterization of Primary Tumor Cells
Isolation and Characterization of Primary Tumor Cells
Bacterial Glycan Recognition by Lectins
Bacterial Glycan Recognition by Lectins
Inhibitory Effect of Plant Extracts on Siderophore Production in Klebsiella Pneumoniae
Inhibitory Effect of Plant Extracts on Siderophore Production in Klebsiella Pneumoniae
Admissions Apply Now