Back close

Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Start Date: Sunday, Mar 01,2009

School: School of Biotechnology

Funded by:Amrita Vishwa Vidyapeetham
Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Divergent oriented synthesis is a strategy which aims to the synthesis of compounds with diverse chemical structures. It is often an alternative to convergent synthesis or linear synthesis. With this intention, the diversity oriented synthesis was developed. In Phytochemistry laboratory our aims is to generate a library of bioactive oxygen heterocyclic compounds by first reacting with a easily available starting material to form set of intermediates, e.g. chalcones, 1,3-diketones.  The next target compounds are generated by suitable transformations of  intermediates, e.g. flavones, flavonols, flavanones, isoflavones and biflavones. This methodology quickly diverges to large numbers of different classes of compounds from simple starting materials. It is also efficient synthesis. The scheme methodology is given below.

diversity-bio-project

Some examples of  compounds synthesised are given below:

  1. chalcones
  2. dihydroflavonols
  3. flavones
  4. flavonol 
  5. isoflavones

Related Projects

Exploring Pseudomonas Bacteriophages for Clinical and Environmental Applications
Exploring Pseudomonas Bacteriophages for Clinical and Environmental Applications
Molecular Structural Studies of Complex Natural Products by LCMS and UV Spectrophotometry
Molecular Structural Studies of Complex Natural Products by LCMS and UV Spectrophotometry
Expression and refolding of Recombinant Staphylococcal Amidases in E. Coli
Expression and refolding of Recombinant Staphylococcal Amidases in E. Coli
Comparison of Anti-microbial Activity of Anti-acne Agents
Comparison of Anti-microbial Activity of Anti-acne Agents
Effects of Nisin in upsurging the adequacy of conventional antibiotics against a few enteric pathogens: An invitro study
Effects of Nisin in upsurging the adequacy of conventional antibiotics against a few enteric pathogens: An invitro study
Admissions Apply Now