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Dr. Sudarslal S.

Associate Professor

Dr. Sudarslal S. currently serves as Associate Professor at the School of Biotechnology.

Qualification: Ph.D
sudarslal@am.amrita.edu

Bio

Dr. Sudarslal S. currently serves as Associate Professor at the School of Biotechnology. He was conferred with a Ph. D. in Biophysics, School of Biosciences, M. G. University, Kerala. Prior to joining Amrita, he served as a Manager at Mass Spectrometry Core Facility, N. C. B. S., Bangalore, India.

Professional Affiliations

  • Life member, Indian Society for Mass Spectrometry.
  • Life member, Proteomics Society of India.
Publications

Book Chapter

Mass Spectrometric Characterization of a Novel Antimicrobial Peptide Isolated from Clitoria Ternatea

Authors : Dr. Bipin Nair, Dr. Sudarslal S., Neethu Ajayakumar, Walter Schrenk, Dr. Sudarslal S.

Publisher : Prospects in Bioscience: Addressing the Issues

Identification, Purification and Mass Spectrometric Characterization of Two Novel Cyclic Peptides from Clitoria ternatea

Authors : Dr. Sudarslal S., Balaram P; Laladhas K. P

Publisher : Biodiversity Conservation - Challenges for the Future

Conference Paper

Isolation and characterization of host binding proteins from Bacillus clausii using mass spectrometry

Authors : Dr. Sanjay Pal, Dr. Sudarslal S., Neethi S, Clinton MU, Arjun S

Publisher : Proceedings of International Conference on Biotechnology for Innovative Applications (Amrita BioQuest 2013)

Conference Proceedings

Isolation and Characterisation of Lipopeptides from a Bacillus subtilis sp. Strain, a marime algal endophyte

Authors : Dr. Sudarslal S., Muralidharan V., Divya Nair, Bipin Nair , Jayashree G

Publisher : Fourth International Seminar on Sustainable Utilisation of Tropical Plant Biomass- Ayur informatics

Isolation and characterization of host-binding proteins from Bacillus calausii using mass spectrometry

Authors : Dr. Sudarslal S.

Publisher : Amrita BioQuest 2013 an International conference on Biotechnology for innovative applications

Journal Article

Kannurin, a Novel Lipopeptide from Bacillus Cereus Strain AK1: Isolation, Structural Evaluation and Antifungal Activities

Authors : Dr. Sudarslal S., K. Ajesh, Arunan, C., and Sreejith, K

Publisher : Journal of Applied Microbiology

Strategy to Enhance Efficacy of Doxorubicin in Solid Tumor Cells by Methyl-β-cyclodextrin: Involvement of p53 and Fas Receptor Ligand Complex

Authors : Dr. Bipin Nair, Dr. Sudarslal S., Muralidharan V., Naoshad Mohammad, Shivendra Vikram Singh, Parmanand Malvi, Balkrishna Chaube, Dipti Athavale, Sudarslal Sadasivan Nair, Manoj Kumar Bhat

Publisher : Scientific reports

Sodium Channel Modulating Activity in a δ-Conotoxin from an Indian Marine Snail

Authors : Dr. Sudarslal S., Majumdar, S., Ramasamy, P., Dhawan, R., Pal, P. P., Ramaswami, M., Lala, A. K., Sikdar, S. K., Sarma, S. P., Krishnan, K. S., and Balaram, P

Publisher : {FEBS} Letters

Anti-oxidant activity of Centella asiatica on lymphoma-bearing mice

Authors : Dr. Jayashree G., Dr. Sudarslal S., Dr. Jayashree G.; Kurup, G.M.; V.B. Jacob

Publisher : Fitoterapia

A Novel 13 Residue Acyclic Peptide from the Marine Snail, Conus Monile, Targets Potassium Channels

Authors : Dr. Sudarslal S., Singaravadivelan, G., Ramasamy, P., Ananda, K., Sarma, S. P., Sikdar, S. K., Krishnan, K. S., and Balaram, P

Publisher : Biochemical and Biophysical Research Communications

Antitumour Property of Vinblastine Monohydrazide

Authors : Dr. Jayashree G., Dr. Sudarslal S., Mathew, A.; Kurup, G. M.; Vasundhara, G

Publisher : Indian Journal of Pharmaceutical Sciences

Solution Structure of δ-Am2766: A Highly Hydrophobic δ-Conotoxin from Conus amadis That Inhibits Inactivation of Neuronal Voltage-Gated Sodium Channels

Authors : Dr. Sudarslal S., S. P. Sarma, G. Kumar, S., Iengar, Prathima, Ramasamy, P., Sikdar, S. K., Krishnan, K. S., and Balaram, P

Publisher : Chemistry Biodiversity

Novel Peptides of Therapeutic Promise from Indian Conidae

Authors : Dr. Sudarslal S., Gowd, K Hanumae; Sabareesh V; S. Sudarslal; Iengar, Prathima; Franklin, Benjamin; Fernando, Antony; Dewan, Kalyan; Ramaswami, Mani; Sarma, Siddhartha P.;Sikdar, Sujit; Balaram, P; Krishnan, K S

Publisher : Annals of the New York Academy of Sciences

Increased Glutathionylated Hemoglobin (HbSSG) in Type 2 Diabetes Subjects with Microangiopathy

Authors : Dr. Sudarslal S., R. Sampathkumar, Balasubramanyam, M., Rema, M., Mohan, V., and Balaram, P

Publisher : Clinical Biochemistry

De Novo Sequencing and Disulfide Mapping of a Bromotryptophan-Containing Conotoxin by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Authors : Dr. Sudarslal S., Nilsson, C. L., Emmett, M. R., Schaub, T. M., Gowd, K. Hanumae, Thakur, S. S., Krishnan, K. S., Balaram, P., and Marshall, A. G

Publisher : Analytical Chemistry

Characterization of Contryphans from Conus Loroisii and Conus Amadis that Target Calcium Channels

Authors : Dr. Sudarslal S., V. Sabareesh, K. Gowd, H., Ramasamy, P., Krishnan, K. S., Sikdar, S. K., and Balaram, P.

Publisher : Peptides

Structural Characterization of an Unusually Stable Cyclic Peptide, Kalata {B2} from Oldenlandia Affinis

Authors : Dr. Sudarslal S., Romanuka, J., Billeter, M., Skjeldal, L., Emmett, M. R., Nilsson, C. L., and Marshall, A. G.

Current Research
  •  Mass Spectrometric Characterization of Bioactive Peptides and Proteins
  •  Mass spectrometry based Proteomic Characterization of Carbonylated Proteins as Indicators of Oxidative Stress
  •  Natural Products as Modulators of Diabetes Associated Endothelial Dysfunctions
  •  Identification and Characterization of the Role of Allium Sativum – Microbiome on the Production of Therapeutic Metabolites.
Awards and Fellowships
  •  Post Doctoral Fellowship from National Science Foundation, USA (2005-2007).
  •  Post Doctoral Fellowship from Department of Biotechnology, Govt. of India, (2001- 2004).
  •  Senior Research Fellowship from Council of Scientific and Industrial Research, Govt. of India, (1999- 2000).
Teaching
  • BIO410/Advanced Discovery Biology/M.Sc. Biotechnology
  • BIO206 / Analytical Biochemistry/ 3 Credits /B.Sc. Biotechnology and B.Sc. Microbiology
  • BIO316 / Basic Proteomics/ 3 Credits /B.Sc. Biotechnology
  • BIO424 / Bioanalytical Techniques/ 3 Credits /M.Sc. Biotechnology
  • BIO212 / Introductory Biophysics/ 2 Credits /B.Sc. Biotechnology

Courses Taught

  • Analytical Biochemistry, Basic Proteomics (Odd Semester)
  • Bioanalytical Techniques, Introductory Biophysics, Advanced Discovery Biology (Even Semester).
Invited Talks
Year of Publication Title
2015 Disulfide bond mapping by mass spectrometry” in the National Colloquium on Nuclear Magnetic Resonance (NMR) Spectroscopy & Mass Spectrometry (MS): Biological Appliations, on July 31, 2015, Organized by Srinivasa Ramanujan Institute for Basic Sciences, Kottayam
2015 Peptidomics: a logical outcome of proteomics” in the National Seminar on New Perspectives in Proteomics, on March 27, 2015, Organized by IU-CGGT, Dept. of Biotechnology, University of Kerala, Thiruvananthapuram
2015 “Primer to HPLC” in the Workshop on HPLC, on March 11, 2015, Organized by Pushpagiri Institute of Medical Science and Research Centre, Thiruvalla.
2014 “Application of Mass Spectrometry in the Study of Proteins” in the UGC sponsored seminar on Interdisciplinary Research in Chemical Sciences, on December 31, 2014, Organized by N.S.S. College, Kottiyam, Thiruvananthapuram.
2014 “Ion Trap Mass Spectrometry” in the KSCSTE sponsored National Seminar on Recent Approaches in Biochemical Research (RABR-2014) on October 29, 2014, Organized by Department of Biochemistry, University of Kerala, Thiruvananthapuram.
2014 “Applications of proteomics in biological research”, in the course work for Ph.D. candidates conducted by School of Biosciences, Mahatma Gandhi University, Kottayam, on July 17, 2014.
2014 “Role of mass spectrometry for petidome research”, in the one day workshop conducted by the Department of Computational Biology and Bioinformatics, Kerala University, Thiruvananthapuram, on June 15, 2014.
2013 “Electrospray Ionization Ion Trap Mass Spectrometry for Cyclic Peptide Characterization” in the Amrita BioQuest 2013 on August 14, 2013, conducted by Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Kollam.
2013 “Applications of spectroscopy in biological research” in the course work for Ph.D. candidates conducted by School of Biosciences, Mahatma Gandhi University, Kottayam, on August 1, 2013.
2013 “Biological mass spectrometry: Fundamentals and applications” in the workshop on NMR and MS organized by Kerala State Council for Science, Technology and Environment and Sophisticated Test and Instrumentation Centre, Cochin University of Science and Technology, Cochin, on July 20, 2013.
2011 “Role of mass spectrometry based proteomics in immunology research” in the National Seminar on Current Concepts in Immunology conducted by St. Thomas College, Kozhencherry on August 19, 2011.
2011 “Proteomics for biological discovery” in the course work for Ph.D. candidates conducted by School of Biosciences, Mahatma Gandhi University, Kottayam, on May 18, 2011.
2011 “Fundamentals of mass spectrometry and proteomics” in the National level refresher course for college and University teachers conducted by Kannur University, on March 05, 2011.
2010 “Mass spectrometers: Magnificent arsenals of analytical world” at the Department of Biotechnology, Manipal University, on August 24, 2010.
2005 “Tandem mass spectrometry in the analysis of abnormal hemoglobins” at the Mar Athanasius College for Advanced Studies, Thiruvalla, on January 25, 2005.
2004 “Characterization of Abnormal Hemoglobins”, at the 11th ISMAS-WS 2004 workshop on Mass Spectrometry held at Shilon Bagh, Shimla, from October 7-12, 2004, organized by Indian Society for Mass Spectrometry.
2004 “Isolation and characterization of biologically active peptides from Indian marine snails”, at the National seminar on new frontiers in marine bioscience research, held at Chennai, organized by National Institute of Ocean Technology, conducted from 22- 23rd January 2004.
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