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Dr. Sudarslal S.

Professor, School of Biotechnology, Amritapuri

Qualification: Ph.D
sudarslal@am.amrita.edu

Bio

Dr. Sudarslal S. currently serves as Professor at the School of Biotechnology. He was conferred with a Ph. D. in Biophysics, School of Biosciences, M. G. University, Kerala. Prior to joining Amrita, he served as a Manager at Mass Spectrometry Core Facility, N. C. B. S., Bangalore, India.

Professional Affiliations

  • Life member, Indian Society for Mass Spectrometry.
  • Life member, Proteomics Society of India.
Publications

Journal Article

Year : 2021

Venomics and antivenomics of Indian spectacled cobra (Naja naja) from the Western Ghats

Cite this Research Publication : Vanuopadath, Muralidharan, Dileepkumar Raveendran, Bipin G Nair and Sudarslal Sadasivan Nair. “Can proteomics of snake venoms help drug discovery? A study on the venom of spectacled cobra (Naja naja) from the Western Ghats”, biorxiv, published in Acta Tropica doi: 10.1016/j.actatropica.2022.106324 (2021).

Publisher : bioRxiv

Year : 2021

Identification of carbonylated proteins from monocytic cells under diabetes-induced stress conditions

Cite this Research Publication : Dr. Bipin G. Nair, Divya Nedungadi, Divya Nair, Mishra, N., and Dr. Sudarslal S., “Identification of carbonylated proteins from monocytic cells under diabetes-induced stress conditions”, Biomedical Chromatography, vol. e5065, 2021.

Publisher : Biomedical Chromatography

Year : 2021

Ginger Extract Activates Caspase Independent Paraptosis in Cancer Cells via ER stress, mitochondrial Dysfunction, AIF Translocation and DNA Damage

Cite this Research Publication : Divya Nedungadi, Anupama Binoy, Vivek Vinod, Muralidharan Vanuopadath, Sudarslal Sadasivan Nair, Bipin G Nair, Nandita Mishra, Ginger extract activates caspase independent paraptosis in cancer cells via ER stress, mitochondrial dysfunction, AIF translocation and DNA damage Nutrition and cancer, 2021, 73 (1), 147-159.

Publisher : Nutrition and Cancer

Year : 2020

Evaluating the Immunological cross-reactivity of Indian polyvalent antivenoms towards the venom of Hypnalehypnale (hump-nosed pit viper) from the Western Ghats

Cite this Research Publication : Muralidharan Vanuopadath, Dileepkumar Raveendran, Bipin Gopalakrishnan Nair, Sudarslal Sadasivan Nair, “Evaluating the Immunological cross-reactivity of Indian polyvalent antivenoms towards the venom of Hypnalehypnale (hump-nosed pit viper) from the Western Ghats”, bioRxiv, 2020.

Publisher : bioRxiv

Year : 2020

Sensitization of hepatocellular carcinoma cells towards doxorubicin and sorafenib is facilitated by glucosedependent alterations in reactive oxygen species, P-glycoprotein and DKK4.

Cite this Research Publication : Surbhi Chouhan, Snahlata Singh, Dipti Athavale, Pranay Ramteke, Muralidharan Vanuopadath, Bipin G Nair, Sudarslal Sadasivan Nair, Manoj Kumar Bhat, “Sensitization of hepatocellular carcinoma cells towards doxorubicin and sorafenib is facilitated by glucosedependent alterations in reactive oxygen species, P-glycoprotein and DKK4.”, Journal of Biosciences, vol. 45, 2020.

Publisher : Journal of Biosciences

Year : 2020

Delineating the venom toxin arsenal of Malabar pit viper (Trimeresurus malabaricus) from the Western Ghats of India and evaluating its immunological cross-reactivity and in vitro cytotoxicity

Cite this Research Publication : Muralidharan Vanuopadath, Shaji, S. Korumadath, Dileepkumar Raveendran, Dr. Bipin G. Nair, and Sudarslal Sadasivan Nair, “Delineating the venom toxin arsenal of Malabar pit viper (Trimeresurus malabaricus) from the Western Ghats of India and evaluating its immunological cross-reactivity and in vitro cytotoxicity”, International Journal of Biological Macromolecules, vol. 148, pp. 1029 - 1045, 2020.

Publisher : International Journal of Biological Macromolecules

Year : 2020

RECK and TIMP-2 mediate inhibition of MMP-2 and MMP-9 by Annona muricata

Cite this Research Publication : Drishya G., Dr. Jyotsna Nambiar, Sanu K. Shaji, Muralidharan Vanuopadath, Achuthan A., Kumar Abishek, Alias Ashna, Ayesha Sherif, Catherine Joseph, Divya P., Damu Sunilkumar, Chinchu Bose, Dr. Sobha V. Nair, S. Sudarslal, Dr. Geetha Kumar, Lakshmi S., and Dr. Bipin G. Nair, “RECK and TIMP-2 mediate inhibition of MMP-2 and MMP-9 by Annona muricata”, Journal of Biosciences, vol. 45, no. 1, pp. 1-11, 2020.

Publisher : Journal of Biosciences

Year : 2019

Ginger extract activates caspase-independent paraptosis in cancer cells via ER stress, mitochondrial dysfunction

Cite this Research Publication : Nedungadi D, Binoy A, Vinod V, Vanuopadath M, Nair SS, Nair BG, Mishra N. Ginger extract activates caspase-independent paraptosis in cancer cells via ER stress, mitochondrial dysfunction, AIF translocation and DNA damage. Nutrition and cancer. 2019:1-13.

Publisher : Nutrition and Cancer, Pp:1-13, 2019

Year : 2019

Phlorotannins from Padina tetrastromatica: structural characterisation and functional studies

Cite this Research Publication : Divya Nair, Muralidharan Vanuopadath, Akshaya Balasubramanian, Akshay Iyer, Shankar Ganesh, Abhishek Nair Anil, Vijesh Vikraman, Prasanth Pillai, Chinchu Bose, Bipin Gopalakrishnan Nair, Jayashree Gopalakrishna Pai & Sudarslal Sadasivan Nair, "Phlorotannins from Padina tetrastromatica: structural characterisation and functional studies.",Journal of Applied Phycology, Volume 31, 3131–3141 (2019). https://doi.org/10.1007/s10811-019-01792-y

Publisher : Journal of Applied Phycology, Volume 31:3131–41, 2019

Year : 2018

Mass spectrometry-assisted venom profiling of Hypnale Hypnale found in the Western Ghats of India incorporating de Novo Sequencing Approaches.

Cite this Research Publication : Muralidharan Vanuopadath, Nithin Sajeev, Athira Radhamony Murali, Nayana Sudish, Nithya Kangosseri, Ivy Rose Sebastian, Nidhi Dalpatraj Jain, Amit Pal, Dileepkumar Raveendran, Dr. Bipin G. Nair, and Sudarslal Sadasivan Nair, “Mass spectrometry-assisted venom profiling of Hypnale hypnale found in the Western Ghats of India incorporating de novo sequencing approaches.”, International Journal of Biological Macromolecules, vol. 118, no. Part B, pp. 1736-1746, 2018

Publisher : International Journal of Biological Macromolecules

Year : 2018

Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa.

Cite this Research Publication : Jayalekshmi H., Omanakuttan, A., Menon, N. D., Muralidharan Vanuopadath, Nair, S. Sadasivan, Corriden, R., Nair, B. G., Nizet, V., and Kumar, G. B., “Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa.”, Sci Rep, vol. 8, no. 1, p. 3437, 2018.

Publisher : Scientific reports

Year : 2017

Mechanistic Understanding of Phenyllactic Acid Mediated Inhibition of Quorum Sensing and Biofilm Development in Pseudomonas Aeruginosa

Cite this Research Publication : M. Chatterjee, D'Morris, S., Paul, V., Warrier, S., Vasudevan, A. Kumar, Muralidharan Vanuopadath, Nair, S. Sadasivan, Dr. Bindhu Paul, Dr. Gopi Mohan C., and Dr. Raja Biswas, “Mechanistic Understanding of Phenyllactic Acid Mediated Inhibition of Quorum Sensing and Biofilm Development in Pseudomonas Aeruginosa”, Appl Microbiol Biotechnol, vol. 101, no. 22, pp. 8223-8236, 2017

Publisher : Appl Microbiol Biotechnol

Year : 2016

Weight control interventions improve therapeutic efficacy of dacarbazine in melanoma by reversing obesity-induced drug resistance

Cite this Research Publication : Parmanand Malvi, Balkrishna Chaube, Shivendra Vikram Singh, Naoshad Mohammad, Vimal Pandey, Maleppillil Vavachan Vijayakumar, Revathy Meenatheril Radhakrishnan, Muralidharan Vanuopadath, Sudarslal Sadasivan Nair, Bipin Gopalakrishnan Nair & Manoj Kumar Bhat, “Weight control interventions improve therapeutic efficacy of dacarbazine in melanoma by reversing obesity-induced drug resistance.”, Cancer Metab, vol. 4, p. 21, 2016.

Publisher : Cancer Metab.

Year : 2016

Post-translational Modifications of Proteins: Biomarkers and Therapeutic Targets for Diabetes Related Complications

Cite this Research Publication : Muralidharan Vanuopadath, Divya Nair, Dr. Bipin G. Nair, and Sudarslal Sadasivan Nair, “Post-translational Modifications of Proteins: Biomarkers and Therapeutic Targets for Diabetes Related Complications”, Current Proteomics, vol. 13, no. 4, pp. 251-270, 2016

Publisher : Current Proteomics.

Year : 2016

Identification and Characterization of a Library of Surfactins and Fengycins from a Marine Endophytic Bacillus sp.

Cite this Research Publication : Divya Nair, Muralidharan Vanuopadath, Dr. Jayashree G., Dr. Bipin G. Nair, and Sudarslal Sadasivan Nair, “Identification and characterization of a library of surfactins and fengycins from a marine endophytic Bacillus sp.”, Journal of basic microbiology, vol. 56, no. 11, pp. 1159–1172, 2016

Publisher : Journal of Basic Microbiology

Year : 2015

Strategy to Enhance Efficacy of Doxorubicin in Solid Tumor Cells by Methyl-β-cyclodextrin: Involvement of p53 and Fas Receptor Ligand Complex

Cite this Research Publication : Naoshad Mohammad, Shivendra Vikram Singh, Parmanand Malvi, Balkrishna Chaube, Dipti Athavale, Muralidharan Vanuopadath, Sudarslal Sadasivan Nair, Dr. Bipin G. Nair, and Manoj Kumar Bhat, “Strategy to enhance efficacy of doxorubicin in solid tumor cells by methyl-β-cyclodextrin: Involvement of p53 and Fas receptor ligand complex”, Scientific reports, vol. 5, 2015

Publisher : Scientific reports

Year : 2013

Kannurin, a Novel Lipopeptide from Bacillus Cereus Strain AK1: Isolation, Structural Evaluation and Antifungal Activities

Cite this Research Publication : K. Ajesh, Sudarslal, S., Arunan, C., and Sreejith, K., “Kannurin, a Novel Lipopeptide from Bacillus Cereus Strain AK1: Isolation, Structural Evaluation and Antifungal Activities”, Journal of Applied Microbiology, vol. 115, pp. 1287–1296, 2013

Publisher : Journal of Applied Microbiology

Year : 2011

Effect of Ester Chemical Structure and Peptide Bond Conformation in Fragmentation Pathways of Differently Metal Cationized Cyclodepsipeptides

Cite this Research Publication : R. Banerjee, Dr. Sudarslal S., Ranganayaki, R. S., and Raghothama, S., “Effect of Ester Chemical Structure and Peptide Bond Conformation in Fragmentation Pathways of Differently Metal Cationized Cyclodepsipeptides”, Org. Biomol. Chem., vol. 9, pp. 6234-6245, 2011.

Publisher : The Royal Society of Chemistry

Year : 2007

Two-dimensional gel separation followed by ESI FT-ICR MS for differential membrane proteome analysis of Borrelia burgdorferi, a causative agent of lyme disease

Cite this Research Publication : Two-dimensional gel separation followed by ESI FT-ICR MS for differential membrane proteome analysis of Borrelia burgdorferi, a causative agent of lyme disease, at the 55th ASMS conference, Indianapolis, from June 3-7, 2007.

Publisher : ASMS conference

Year : 2006

Structural Characterization of an Unusually Stable Cyclic Peptide, Kalata B2 from Oldenlandia Affinis

Publisher : Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year : 2006

De Novo Sequencing and Disulfide Mapping of a Bromotryptophan-Containing Conotoxin by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Cite this Research Publication : S. Sudarslal, Nilsson, C. L., Emmett, M. R., Schaub, T. M., Gowd, K. Hanumae, Thakur, S. S., Krishnan, K. S., Balaram, P., and Marshall, A. G., “De Novo Sequencing and Disulfide Mapping of a Bromotryptophan-Containing Conotoxin by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry”, Analytical Chemistry, vol. 78, pp. 8082-8088, 2006

Publisher : Analytical Chemistry

Year : 2006

Characterization of Contryphans from Conus Loroisii and Conus Amadis that Target Calcium Channels

Cite this Research Publication : V. Sabareesh, K. Gowd, H., Ramasamy, P., Sudarslal, S., Krishnan, K. S., Sikdar, S. K., and Balaram, P., “Characterization of Contryphans from Conus Loroisii and Conus Amadis that Target Calcium Channels”, Peptides, vol. 27, pp. 2647 - 2654, 2006

Publisher : Peptides

Year : 2006

Structural Characterization of an Unusually Stable Cyclic Peptide, Kalata {B2} from Oldenlandia Affinis

Cite this Research Publication : S. Sudarslal, Romanuka, J., Billeter, M., Skjeldal, L., Emmett, M. R., Nilsson, C. L., and Marshall, A. G., “Structural Characterization of an Unusually Stable Cyclic Peptide, Kalata \{B2\} from Oldenlandia Affinis”, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, vol. 1764, pp. 1568 - 1576, 2006

Year : 2005

Solution Structure of δ-Am2766: A Highly Hydrophobic δ-Conotoxin from Conus amadis That Inhibits Inactivation of Neuronal Voltage-Gated Sodium Channels

Cite this Research Publication : S. P. Sarma, G. Kumar, S., Sudarslal, S., Iengar, Prathima, Ramasamy, P., Sikdar, S. K., Krishnan, K. S., and Balaram, P., “Solution Structure of δ-Am2766: A Highly Hydrophobic δ-Conotoxin from Conus amadis That Inhibits Inactivation of Neuronal Voltage-Gated Sodium Channels”, Chemistry & Biodiversity, vol. 2, pp. 535–556, 2005

Publisher : WILEY-VCH Verlag

Year : 2005

Novel Peptides of Therapeutic Promise from Indian Conidae

Cite this Research Publication : Gowd, K Hanumae; Sabareesh V; S. Sudarslal; Iengar, Prathima; Franklin, Benjamin; Fernando, Antony; Dewan, Kalyan; Ramaswami, Mani; Sarma, Siddhartha P.;Sikdar, Sujit; Balaram, P; Krishnan, K S, “Novel Peptides of Therapeutic Promise from Indian Conidae”, Annals of the New York Academy of Sciences, vol. 1056, pp. 462–473, 2005

Publisher : Blackwell Publishing Ltd

Year : 2005

Increased Glutathionylated Hemoglobin (HbSSG) in Type 2 Diabetes Subjects with Microangiopathy

Cite this Research Publication : R. Sampathkumar, Balasubramanyam, M., Sudarslal, S., Rema, M., Mohan, V., and Balaram, P., “Increased Glutathionylated Hemoglobin (HbSSG) in Type 2 Diabetes Subjects with Microangiopathy”, Clinical Biochemistry, vol. 38, pp. 892 - 899, 2005

Publisher : Clinical Biochemistry

Year : 2004

A Novel 13 Residue Acyclic Peptide from the Marine Snail, Conus Monile, Targets Potassium Channels

Cite this Research Publication : S. Sudarslal, Singaravadivelan, G., Ramasamy, P., Ananda, K., Sarma, S. P., Sikdar, S. K., Krishnan, K. S., and Balaram, P., “A Novel 13 Residue Acyclic Peptide from the Marine Snail, Conus Monile, Targets Potassium Channels”, Biochemical and Biophysical Research Communications, vol. 317, pp. 682 - 688, 2004

Publisher : Biochemical and Biophysical Research Communications

Year : 2004

Antitumour Property of Vinblastine Monohydrazide

Cite this Research Publication : A. Mathew, Kurup, G. M., Dr. Jayashree G., Dr. Sudarslal S., and Vasundhara, G., “Antitumour Property of Vinblastine Monohydrazide”, Indian Journal of Pharmaceutical Sciences, vol. 66, pp. 117–120, 2004.

Publisher : MedKnow Publications and Media

Year : 2003

Sodium Channel Modulating Activity in a δ-Conotoxin from an Indian Marine Snail

Cite this Research Publication : S. Sudarslal, Majumdar, S., Ramasamy, P., Dhawan, R., Pal, P. P., Ramaswami, M., Lala, A. K., Sikdar, S. K., Sarma, S. P., Krishnan, K. S., and Balaram, P., “Sodium Channel Modulating Activity in a δ-Conotoxin from an Indian Marine Snail”, \{FEBS\} Letters, vol. 553, pp. 209 - 212, 2003

Publisher : {FEBS} Letters

Year : 2003

Anti-oxidant activity of Centella asiatica on lymphoma-bearing mice

Cite this Research Publication : Dr. Jayashree G., Kurup, G. M., Dr. Sudarslal S., and Jacob, V. B., “Anti-oxidant activity of Centella asiatica on lymphoma-bearing mice”, Fitoterapia, vol. 74, pp. 431 - 434, 2003.

Publisher : Fitoterapia

Conference Paper

Year : 2013

Isolation and characterization of host binding proteins from Bacillus clausii using mass spectrometry

Cite this Research Publication : A. L, K, A., S, A., MU, C., S, N., Dr. Sudarslal S., and Dr. Sanjay Pal, “Isolation and characterization of host binding proteins from Bacillus clausii using mass spectrometry”, in Proceedings of International Conference on Biotechnology for Innovative Applications (Amrita BioQuest 2013), 2013.

Publisher : Amrita BioQuest

Conference Proceedings

Year : 2018

Proteomics investigation of complex venom toxin arsenal of Hypnale hypnale from the Western Ghats of India

Cite this Research Publication : Muralidharan Vanuopadath, Dileepkumar Raveendran, Bipin Gopalakrishnan Nair, Sudarslal Sadasivan Nair, Proteomics investigation of complex venom toxin arsenal of Hypnale hypnale from the Western Ghats of India, 10th annual meeting of proteomics society of India-International conference on proteomics for cell biology and molecular medicine, NCCS, Pune, India, December 12-14, 2018.

Year : 2018

Proteomic investigation of complex venom toxin arsenal of Hypnalehypnale from the Western Ghats of India

Cite this Research Publication : V. M., D., R., B.G., N., and S.S., N., “Proteomic investigation of complex venom toxin arsenal of Hypnalehypnale from the Western Ghats of India”, 10th annual meeting of proteomics society of India-International conference on proteomics for cell biology and molecular medicine, NCCS. Pune, India, 2018.

Publisher : NCCS. Pune

Year : 2017

Mass spectrometry-based quantitation of oxidized and reduced glutathione under diabetes-induced oxidative stress conditions

Cite this Research Publication : Muralidharan Vanuopadath, Bipin Gopalakrishnan Nair, Sudarslal Sadasivan Nair, Mass spectrometry-based quantitation of oxidized and reduced glutathione under diabetes-induced oxidative stress conditions, 27th Swadeshi Science Congress, Swadeshi Science Movement-Kerala, India, November 7-9, 2017.

Year : 2017

Proteomic investigation of Trimeresurus malabaricus venom and its comparative functional analysis using Daboia Russelii venom, SnakeSymp-Snake venom research and snakebite therapy

Cite this Research Publication : Muralidharan Vanuopadath, Aswathy Alangode, Karthika Rajan, Nithin Sajeev, Dileepkumar Raveendran, Martein Reick, Margaret Reick, Bipin Gopalakrishnan Nair, Sudarslal Sadasivan Nair, Proteomic investigation of Trimeresurus malabaricus venom and its comparative functional analysis using Daboia Russelii venom, SnakeSymp-Snake venom research and snakebite therapy, Centre for Cellular and Molecular Biology, Hyderabad, India, December 1-3, 2017.

Year : 2017

Proteomic investigation of Trimeresurusmalabaricus venom and its comparative functional analysis using Daboia Russelii venom, SnakeSymp- Snake venom research and snakebite therapy

Cite this Research Publication : V. M., A., A., K., R., N., S., and , “Proteomic investigation of Trimeresurusmalabaricus venom and its comparative functional analysis using Daboia Russelii venom, SnakeSymp- Snake venom research and snakebite therapy”, Centre for Cellular and Molecular Biology. Hyderabad, India, 2017.

Publisher : Centre for Cellular and Molecular Biology

Year : 2014

Isolation and Characterisation of Lipopeptides from a Bacillus subtilis sp. Strain, a marime algal endophyte

Cite this Research Publication : Divya Nair, Muralidharan Vanuopadath, Dr. Bipin G. Nair, Jayashree G, and Sudarslal S, “Isolation and Characterisation of Lipopeptides from a Bacillus subtilis sp. Strain, a marime algal endophyte”, Fourth International Seminar on Sustainable Utilisation of Tropical Plant Biomass- Ayur informatics. pp. 89-91, 2014.

Publisher : Fourth International Seminar on Sustainable Utilisation of Tropical Plant Biomass- Ayur informatics

Year : 2013

Isolation and characterization of host-binding proteins from Bacillus calausii using mass spectrometry

Cite this Research Publication : Isolation and characterization of host-binding proteins from Bacillus calausii using mass spectrometry at the Amrita BioQuest 2013 an International conference on Biotechnology for innovative applications, Kollam, from August 10-14, 2013.

Publisher : Amrita BioQuest

Year : 2013

Isolation and characterization of host-binding proteins from Bacillus calausii using mass spectrometry

Cite this Research Publication : Isolation and characterization of host-binding proteins from Bacillus calausii using mass spectrometry at the Amrita BioQuest 2013 an International conference on Biotechnology for innovative applications, Kollam, from August 10-14, 2013.

Publisher : Amrita BioQuest 2013 an International conference on Biotechnology for innovative applications

Year : 2013

Mass spectrometric characterization of lipopeptides from Bacilluscereus-AK1

Cite this Research Publication : Mass spectrometric characterization of lipopeptides from Bacillus cereus-AK1 at the Amrita BioQuest 2013 an International conference on Biotechnology for innovative applications, Kollam, from August 10-14, 2013.

Publisher : Amrita Bioquest

Year : 2012

Identification, purification and characterization of two novel cyclic peptides from Clitoria ternatea

Cite this Research Publication : Identification, purification and characterization of two novel cyclic peptides from Clitoria ternatea at the National Biodiversity Conference-2012, Thiruvananthapuram, from December 27-30, 2012.

Publisher : National Biodiversity Conference

Year : 2007

A middle-down approach to determine disulfide connectivity of GM2 activator protein by FT-ICR mass spectrometry

Cite this Research Publication : A middle-down approach to determine disulfide connectivity of GM2 activator protein by FT-ICR mass spectrometry, at the 6th North American FT-ICR MS conference, Tahoe city, California, from April 1-5, 2007.

Publisher : 6th North American FT-ICR MS conference

Year : 2007

Two-dimensional gel separation followed by ESI FT-ICR MS for differential membrane proteome analysis of Borrelia burgdorferi, a causative agent of lyme disease

Cite this Research Publication : Two-dimensional gel separation followed by ESI FT-ICR MS for differential membrane proteome analysis of Borrelia burgdorferi, a causative agent of lyme disease, at the 55th ASMS conference, Indianapolis, from June 3-7, 2007.

Publisher : ASMS conference

Year : 2006

FT-ICR MS-based structural characterization of a novel conotoxin from Conus monile: Determination of bromotryptophan by use of electron capture dissociation

Cite this Research Publication : FT-ICR MS-based structural characterization of a novel conotoxin from Conus monile: Determination of bromotryptophan by use of electron capture dissociation, at the 54th ASMS conference, Seattle, Washington, from May 28 to June 1, 2006.

Publisher : 54th ASMS conference

Year : 2005

Activated Ion-Electron Capture Dissociation of Kalata B2, a cyclic peptide containing three disulfide bonds

Cite this Research Publication : Activated Ion-Electron Capture Dissociation of Kalata B2, a cyclic peptide containing three disulfide bonds, at the 53rd ASMS conference on Mass Spectrometry, San Antonio, Texas, from June 5-9, 2005.

Publisher : 53rd ASMS conference on Mass Spectrometry

Year : 2004

Isolation and characterization of biologically active peptides from Indian marine snails

Cite this Research Publication : Isolation and characterization of biologically active peptides from Indian marine snails, at the National seminar on new frontiers in marine bioscience research, Chennai, from January 22-23, 2004.

Publisher : National seminar on new frontiers in marine bioscience research

Year : 2004

Electrospray ionization mass spectrometry in the analysis of β- thalassemia and hemoglobin abnormalities

Cite this Research Publication : Electrospray ionization mass spectrometry in the analysis of β- thalassemia and hemoglobin abnormalities, at the 11th ISMAS-WS 2004 workshop on Mass Spectrometry, Shilon Bagh, Shimla, from October 7-12, 2004.

Publisher : 11th ISMAS-WS 2004 workshop on Mass Spectrometry

Year : 2004

Sequencing of Conus peptides by mass spectral methods, at the Keystone Symposia

Cite this Research Publication : Sequencing of Conus peptides by mass spectral methods, at the Keystone Symposia, Santa Fe, USA, from 14- 19th February 2004.

Publisher : Keystone Symposia, Santa Fe, USA

Year : 1997

Anti-tumor property of L-asparaginase

Cite this Research Publication : Anti-tumor property of L-asparaginase, at the Ninth Kerala Science Congress, Trivandrum, from January 27- 29, 1997.

Publisher : Ninth Kerala Science Congress

Book Chapter

Year : 2015

Identification, Purification and Mass Spectrometric Characterization of Two Novel Cyclic Peptides from Clitoria ternatea

Cite this Research Publication : S. Sudarslal, Balaram P; Laladhas K. P., “Identification, Purification and Mass Spectrometric Characterization of Two Novel Cyclic Peptides from Clitoria ternatea”, in Biodiversity Conservation - Challenges for the Future, vol. 209-216, Bentham E-Books, 2015

Publisher : Biodiversity Conservation - Challenges for the Future

Year : 2013

Mass Spectrometric Characterization of a Novel Antimicrobial Peptide Isolated from Clitoria Ternatea

Cite this Research Publication : Neethu Ajayakumar, Walter Schrenk, Dr. Bipin G. Nair, and Dr. Sudarslal S., “Mass Spectrometric Characterization of a Novel Antimicrobial Peptide Isolated from Clitoria Ternatea”, in Prospects in Bioscience: Addressing the Issues, A. Sabu and Augustine, A., Eds. Springer India, 2013, pp. 251-256.

Publisher : Prospects in Bioscience: Addressing the Issues

Other

Year : 2019

Chromatography- Fundamentals and Applications

Publisher : SreeNeelakanta Govt. Sanskrit College

Year : 2018

Mass Spectrometers- New Generation Sniffer Dogs for Biomolecular Discovery

Publisher : Government Arts and Science College

Year : 2017

Mass spectrometers- Next generation sniffer dogs and beyond

Publisher : Sree Narayana College

Year : 2017

ExBiological Mass Spectrometry: A Bird’s-eye view

Publisher : Srinivasa Ramanujan Institute for Basic Sciences

Year : 2015

Primer to HPLC

Publisher : Pushpagiri Institute of Medical Science and Research Centre

Year : 2015

Peptidomics: a logical outcome of proteomics

Publisher : University of Kerala

Year : 2015

Disulfide bond mapping by mass spectrometry

Publisher : Srinivasa Ramanujan Institute for Basic Sciences

Year : 2014

Role of mass spectrometry for petidome research

Publisher : Kerala University

Year : 2014

Applications of proteomics in biological research

Publisher : Mahatma Gandhi University

Year : 2014

Ion Trap Mass Spectrometry

Publisher : University of Kerala

Year : 2014

Application of Mass Spectrometry in the Study of Proteins

Publisher : N.S.S. College, Kottiyam

Year : 2013

Biological mass spectrometry: Fundamentals and applications

Publisher : Cochin University of Science and Technology

Year : 2013

Applications of spectroscopy in biological research

Publisher : Mahatma Gandhi University

Year : 2011

Fundamentals of mass spectrometry and proteomics

Publisher : Kannur University

Year : 2011

Proteomics for biological discovery

Publisher : Mahatma Gandhi University

Year : 2010

Mass spectrometers: Magnificent arsenals of analytical world

Publisher : Manipal University

Year : 2005

Tandem mass spectrometry in the analysis of abnormal hemoglobins

Publisher : Mar Athanasius College for Advanced Studies

Year : 2004

Characterization of Abnormal Hemoglobins

Publisher : Indian Society for Mass Spectrometry

Current Research
  •  Mass Spectrometric Characterization of Bioactive Peptides and Proteins
  •  Mass spectrometry based Proteomic Characterization of Carbonylated Proteins as Indicators of Oxidative Stress
  •  Natural Products as Modulators of Diabetes Associated Endothelial Dysfunctions
  •  Identification and Characterization of the Role of Allium Sativum – Microbiome on the Production of Therapeutic Metabolites.
Awards and Fellowships
  •  Post Doctoral Fellowship from National Science Foundation, USA (2005-2007).
  •  Post Doctoral Fellowship from Department of Biotechnology, Govt. of India, (2001- 2004).
  •  Senior Research Fellowship from Council of Scientific and Industrial Research, Govt. of India, (1999- 2000).
Teaching
  • BIO410/Advanced Discovery Biology/M.Sc. Biotechnology
  • BIO206 / Analytical Biochemistry/ 3 Credits /B.Sc. Biotechnology and B.Sc. Microbiology
  • BIO316 / Basic Proteomics/ 3 Credits /B.Sc. Biotechnology
  • BIO424 / Bioanalytical Techniques/ 3 Credits /M.Sc. Biotechnology
  • BIO212 / Introductory Biophysics/ 2 Credits /B.Sc. Biotechnology

Courses Taught

  • Analytical Biochemistry, Basic Proteomics (Odd Semester)
  • Bioanalytical Techniques, Introductory Biophysics, Advanced Discovery Biology (Even Semester).
Invited Talks
Year of Publication Title
2015 Disulfide bond mapping by mass spectrometry” in the National Colloquium on Nuclear Magnetic Resonance (NMR) Spectroscopy & Mass Spectrometry (MS): Biological Appliations, on July 31, 2015, Organized by Srinivasa Ramanujan Institute for Basic Sciences, Kottayam
2015 Peptidomics: a logical outcome of proteomics” in the National Seminar on New Perspectives in Proteomics, on March 27, 2015, Organized by IU-CGGT, Dept. of Biotechnology, University of Kerala, Thiruvananthapuram
2015 “Primer to HPLC” in the Workshop on HPLC, on March 11, 2015, Organized by Pushpagiri Institute of Medical Science and Research Centre, Thiruvalla.
2014 “Application of Mass Spectrometry in the Study of Proteins” in the UGC sponsored seminar on Interdisciplinary Research in Chemical Sciences, on December 31, 2014, Organized by N.S.S. College, Kottiyam, Thiruvananthapuram.
2014 “Ion Trap Mass Spectrometry” in the KSCSTE sponsored National Seminar on Recent Approaches in Biochemical Research (RABR-2014) on October 29, 2014, Organized by Department of Biochemistry, University of Kerala, Thiruvananthapuram.
2014 “Applications of proteomics in biological research”, in the course work for Ph.D. candidates conducted by School of Biosciences, Mahatma Gandhi University, Kottayam, on July 17, 2014.
2014 “Role of mass spectrometry for petidome research”, in the one day workshop conducted by the Department of Computational Biology and Bioinformatics, Kerala University, Thiruvananthapuram, on June 15, 2014.
2013 “Electrospray Ionization Ion Trap Mass Spectrometry for Cyclic Peptide Characterization” in the Amrita BioQuest 2013 on August 14, 2013, conducted by Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Kollam.
2013 “Applications of spectroscopy in biological research” in the course work for Ph.D. candidates conducted by School of Biosciences, Mahatma Gandhi University, Kottayam, on August 1, 2013.
2013 “Biological mass spectrometry: Fundamentals and applications” in the workshop on NMR and MS organized by Kerala State Council for Science, Technology and Environment and Sophisticated Test and Instrumentation Centre, Cochin University of Science and Technology, Cochin, on July 20, 2013.
2011 “Role of mass spectrometry based proteomics in immunology research” in the National Seminar on Current Concepts in Immunology conducted by St. Thomas College, Kozhencherry on August 19, 2011.
2011 “Proteomics for biological discovery” in the course work for Ph.D. candidates conducted by School of Biosciences, Mahatma Gandhi University, Kottayam, on May 18, 2011.
2011 “Fundamentals of mass spectrometry and proteomics” in the National level refresher course for college and University teachers conducted by Kannur University, on March 05, 2011.
2010 “Mass spectrometers: Magnificent arsenals of analytical world” at the Department of Biotechnology, Manipal University, on August 24, 2010.
2005 “Tandem mass spectrometry in the analysis of abnormal hemoglobins” at the Mar Athanasius College for Advanced Studies, Thiruvalla, on January 25, 2005.
2004 “Characterization of Abnormal Hemoglobins”, at the 11th ISMAS-WS 2004 workshop on Mass Spectrometry held at Shilon Bagh, Shimla, from October 7-12, 2004, organized by Indian Society for Mass Spectrometry.
2004 “Isolation and characterization of biologically active peptides from Indian marine snails”, at the National seminar on new frontiers in marine bioscience research, held at Chennai, organized by National Institute of Ocean Technology, conducted from 22- 23rd January 2004.
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