Back close

Dr. Sheela Nampoothiri

Professor, Department of Paediatrics, Amrita School of Medicine, Kochi

Qualification: MBBS, DCH, Dip NB (Paed), MSc Medical Genetics (Glasgow)
sheelanampoothiri@aims.amrita.edu

Bio

Dr. Sheela Nampoothiri currently serves as Professor at the Department of Paediatrics, Amrita School of Medicine, Kochi.

Languages Known

  • English
  • Malayalam
Publications

Journal Article

Year : 2019

Variants in the Transcriptional Corepressor BCORL1 are Associated with an X-linked Disorder of Intellectual Disability, Dysmorphic Features, and Behavioral Abnormalities

Cite this Research Publication : A. Shukla, Girisha, K. M., Somashekar, P. H., Dr. Sheela Nampoothiri, McClellan, R., and Vernon, H. J., “Variants in the Transcriptional Corepressor BCORL1 are Associated with an X-linked Disorder of Intellectual Disability, Dysmorphic Features, and Behavioral Abnormalities”, Am J Med Genet A, vol. 179, no. 5, pp. 870-874, 2019.

Publisher : Am J Med Genet A

Year : 2019

Ptosis as a Unique Hallmark for Autosomal Recessive WNT1-associated Osteogenesis Imperfecta

Cite this Research Publication : Dr. Sheela Nampoothiri, Guillemyn, B., Elcioglu, N., Jagadeesh, S., Dhanya Yesodharan, Suresh, B., Turan, S., Symoens, S., and Malfait, F., “Ptosis as a Unique Hallmark for Autosomal Recessive WNT1-associated Osteogenesis Imperfecta”, Am J Med Genet A, vol. 179, no. 6, pp. 908-914, 2019.


Publisher : Am J Med Genet A

Year : 2019

Novel Genotype-electroclinical Phenotype Correlations in Sporadic Early-onset Childhood Myoclonic-atonic Epilepsy

Cite this Research Publication : S. P. Babu, Menon, R. N., Asranna, A., Dr. Sheela Nampoothiri, Radhakrishnan, A., Cherian, A., and Thomas, S. V., “Novel Genotype-electroclinical Phenotype Correlations in Sporadic Early-onset Childhood Myoclonic-atonic Epilepsy”, Neurol India, vol. 67, no. 1, pp. 264-267, 2019.


Publisher : Neurol India

Year : 2019

Multi-gene Testing in Neurological Disorders Showed an Improved Diagnostic Yield: Data from Over 1000 Indian Patients.

Cite this Research Publication : A. Ganapathy, Mishra, A., Soni, M. Rani, Kumar, P., Sadagopan, M., Kanthi, A. Vittal, Patric, I. Rosetta Pi, Sobha George, Sridharan, A., Thyagarajan, T. C., Aswathy, S. L., Vidya, H. K., Chinnappa, S. M., Nayanala, S., Prakash, M. B., Raghavendrachar, V. G., Parulekar, M., Gowda, V. K., Dr. Sheela Nampoothiri, Menon, R. N., Pachat, D., Udani, V., Naik, N., Kamate, M., A Devi, R. Rama, Kunju, P. A. Mohammed, Nair, M., Hegde, A. Udwadia, M Kumar, P., Sundaram, S., Tilak, P., Puri, R. D., Shah, K., Sheth, J., Hasan, Q., Sheth, F., Agrawal, P., Katragadda, S., Veeramachaneni, V., Chandru, V., Hariharan, R., and Mannan, A. U., “Multi-gene Testing in Neurological Disorders Showed an Improved Diagnostic Yield: Data from Over 1000 Indian Patients.”, J Neurol, 2019.


Publisher : J Neurol

Year : 2019

Hypomorphic Mutations in TONSL Cause SPONASTRIME Dysplasia.

Cite this Research Publication : H. Ryung Chang, Cho, S. Yoon, Lee, J. Hoon, Lee, E., Seo, J., Lee, H. Ran, Cavalcanti, D. P., Mäkitie, O., Valta, H., Girisha, K. M., Lee, C., Neethukrishna, K., Bhavani, G. S., Shukla, A., Dr. Sheela Nampoothiri, Phadke, S. R., Park, M. Jung, Ikegawa, S., Wang, Z., Higgs, M. R., Stewart, G. S., Jung, E., Lee, M. - S., Park, J. Hoon, Lee, E. A., Kim, H., Myung, K., Jeon, W., Lee, K., Kim, D., Kim, O. - H., Choi, M., Lee, H. - W., Kim, Y., and Cho, T. - J., “Hypomorphic Mutations in TONSL Cause SPONASTRIME Dysplasia.”, Am J Hum Genet, vol. 104, no. 3, pp. 439-453, 2019.

Publisher : Am J Hum Genet

Year : 2019

Gaucher Disease: Single Gene Molecular Characterization of One-hundred Indian Patients Reveals Novel Variants and the Most Prevalent Mutation

Cite this Research Publication : J. Sheth, Bhavsar, R., Mistri, M., Pancholi, D., Bavdekar, A., Dalal, A., Ranganath, P., Girisha, K. M., Shukla, A., Phadke, S., Puri, R., Panigrahi, I., Kaur, A., Muranjan, M., Goyal, M., Ramadevi, R., Shah, R., Dr. Sheela Nampoothiri, Danda, S., Datar, C., Kapoor, S., Bhatwadekar, S., and Sheth, F., “Gaucher Disease: Single Gene Molecular Characterization of One-hundred Indian Patients Reveals Novel Variants and the Most Prevalent Mutation”, BMC Med Genet, vol. 20, no. 1, p. 31, 2019.

Publisher : BMC Med Genet

Year : 2019

First International Conference on RASopathies and Neurofibromatoses in Asia: Identification and Advances of New Therapeutics

Cite this Research Publication : K. A. Rauen, Alsaegh, A., Ben-Shachar, S., Berman, Y., Blakeley, J., Cordeiro, I., Elgersma, Y., D Evans, G., Fisher, M. J., Frayling, I. M., George, J., Huson, S. M., Kerr, B., Khire, U., Korf, B., Legius, E., Messiaen, L., van Minkelen, R., Dr. Sheela Nampoothiri, Ngeow, J., Parada, L. F., Phadke, S., Pillai, A., Plotkin, S. R., Puri, R., Raji, A., Ramesh, V., Ratner, N., Shankar, S. P., Sharda, S., Tambe, A., Vikkula, M., Widemann, B. C., Wolkenstein, P., and Upadhyaya, M., “First International Conference on RASopathies and Neurofibromatoses in Asia: Identification and Advances of New Therapeutics”, Am J Med Genet A, vol. 179, no. 6, pp. 1091-1097, 2019.

Publisher : Am J Med Genet A

Year : 2019

Does the clinical phenotype of mucolipidosis-IIIγ differ from its αβ counterpart?: supporting facts in a cohort of 18 patients.

Cite this Research Publication : S. Nampoothiri, Elcioglu, N. H., Koca, S. S., Dhanya Yesodharan, Kk, C., Dr. Vinod Krishnan, Bhat, M., Natasha Radhakrishnan, Kappanayil, M., Sheth, J. J., Alves, S., Coutinho, F., Friez, M. J., Pauli, R. M., Unger, S., Superti-Furga, A., Leroy, J. G., and Cathey, S. S., “Does the clinical phenotype of mucolipidosis-IIIγ differ from its αβ counterpart?: supporting facts in a cohort of 18 patients.”, Clin Dysmorphol, vol. 28, no. 1, pp. 7-16, 2019.

Publisher : Clin Dysmorphol

Year : 2018

Mitochondrial Acetoacetyl-CoA Thiolase Enzyme Deficiency in a 9-month Old Boy: Atypical Urinary Metabolic Profile with a Novel Homozygous Mutation in ACAT1 Gene

Cite this Research Publication : S. Sundaram, Nair, M., Dr. Sheela Nampoothiri, and Menon, R. N., “Mitochondrial Acetoacetyl-CoA Thiolase Enzyme Deficiency in a 9-month Old Boy: Atypical Urinary Metabolic Profile with a Novel Homozygous Mutation in ACAT1 Gene”, Neurol India, vol. 66, no. 6, pp. 1802-1804, 2018.

Publisher : Neurol India .

Year : 2018

Extensive Extrapulvinar Calcification in Fabry Disease.

Cite this Research Publication : J. Baishya, Kesav, P., Dr. Sheela Nampoothiri, Sreedharan, S. Erat, and Sylaja, P. N., “Extensive Extrapulvinar Calcification in Fabry Disease.”, Ann Indian Acad Neurol, vol. 21, no. 4, pp. 309-310, 2018.

Publisher : Ann Indian Acad Neurol .

Year : 2018

Elsahy-Waters syndrome is caused by biallelic mutations in CDH11.

Cite this Research Publication : F. L. Harms, Nampoothiri, S., Anazi, S., Dhanya Yesodharan, Alawi, M., Kutsche, K., and Alkuraya, F. S., “Elsahy-Waters syndrome is caused by biallelic mutations in CDH11.”, Am J Med Genet A, vol. 176, no. 2, pp. 477-482, 2018.

Publisher : Am J Med Genet A

Year : 2017

WRN Mutation Update: Mutation Spectrum, Patient Registries, and Translational Prospects.

Cite this Research Publication : K. Yokote, Chanprasert, S., Lee, L., Eirich, K., Takemoto, M., Watanabe, A., Koizumi, N., Lessel, D., Mori, T., Hisama, F. M., Ladd, P. D., Angle, B., Baris, H., Cefle, K., Palanduz, S., Ozturk, S., Chateau, A., Deguchi, K., Easwar, T. K. M., Federico, A., Fox, A., Grebe, T. A., Hay, B., Nampoothiri, S., Seiter, K., Streeten, E., Piña-Aguilar, R. E., Poke, G., Poot, M., Posmyk, R., Martin, G. M., Kubisch, C., Schindler, D., and Oshima, J., “WRN Mutation Update: Mutation Spectrum, Patient Registries, and Translational Prospects.”, Hum Mutat, vol. 38, no. 1, pp. 7-15, 2017.

Publisher : Hum Mutat,

Year : 2017

Plexiform Neurofibroma of Clitoris.

Cite this Research Publication : Dhanya Yesodharan, Sudarsanan, B., Jojo, A., Abraham, M., Bhavani, N., Mathews, H., and Nampoothiri, S., “Plexiform Neurofibroma of Clitoris.”, J Pediatr Genet, vol. 6, no. 4, pp. 244-246, 2017.

Publisher : J Pediatr Genet

Year : 2017

Hyperphosphatasia with Mental Retardation Syndrome Due to a Novel Mutation in .

Cite this Research Publication : S. Nampoothiri, Hebbar, M., Roy, A. Grace, Kochumon, S. P., Bielas, S., Shukla, A., and Girisha, K. M., “Hyperphosphatasia with Mental Retardation Syndrome Due to a Novel Mutation in .”, J Pediatr Genet, vol. 6, no. 3, pp. 191-193, 2017.

Publisher : J Pediatr Genet

Year : 2016

Smith-Magenis Syndrome: Face Speaks.

Cite this Research Publication : R. Gupta, Gupta, N., Nampoothiri, S., Mandal, K., Kishore, Y., Sharma, P., Kabra, M., and Phadke, S. R., “Smith-Magenis Syndrome: Face Speaks.”, Indian J Pediatr, vol. 83, no. 6, pp. 589-93, 2016.

Publisher : Indian J Pediatr

Year : 2016

Prenatal diagnosis of amniotic band syndrome.

Cite this Research Publication : L. Devi Padmanabhan, Hamza, Z. V., Thampi, M. Venugopala, and Nampoothiri, S., “Prenatal diagnosis of amniotic band syndrome.”, Indian J Radiol Imaging, vol. 26, no. 1, pp. 63-6, 2016.

Publisher : Indian J Radiol Imaging

Year : 2016

Identification and characterization of 20 novel pathogenic variants in 60 unrelated Indian patients with mucopolysaccharidoses type I and type II.

Cite this Research Publication : A. Uttarilli, Ranganath, P., Matta, D., J Jain, M. Nurul, Prasad, K., Babu, A. S., Girisha, K. M., Verma, I. C., Phadke, S. R., Mandal, K., Puri, R. D., Aggarwal, S., Danda, S., Sankar, V. H., Kapoor, S., Bhat, M., Gowrishankar, K., Hasan, A. Q., Nair, M., Nampoothiri, S., and Dalal, A., “Identification and characterization of 20 novel pathogenic variants in 60 unrelated Indian patients with mucopolysaccharidoses type I and type II.”, Clin Genet, vol. 90, no. 6, pp. 496-508, 2016.

Publisher : Clin Genet

Year : 2016

Heterozygous Complete NIPBL Gene Deletion in Cornelia de Lange Syndrome: First Case Report from India

Cite this Research Publication : S. Bajaj, Nampoothiri, S., Yesodharan, D., Gambhir, P., and Ranade, S., “Heterozygous Complete NIPBL Gene Deletion in Cornelia de Lange Syndrome: First Case Report from India”, International Journal of Human Genetics, vol. 16, pp. 61-69, 2016.

Publisher : International Journal of Human Genetics, Routledge.

Year : 2016

Characterization of Greater Middle Eastern Genetic Variation for Enhanced Disease Gene Discovery

Cite this Research Publication : S. EM, A, H., Y, I., and S, N., “Characterization of Greater Middle Eastern Genetic Variation for Enhanced Disease Gene Discovery”, Nat Genet. , vol. 48, no. 9, pp. 1071-6, 2016.

Publisher : Nat Genet.

Year : 2016

Brief Report: Peripheral Osteolysis in Adults Linked to ASAH1 (Acid Ceramidase) Mutations: A New Presentation of Farber’s Disease.

Cite this Research Publication : L. Bonafé, Kariminejad, A., Li, J., Royer-Bertrand, B., Garcia, V., Mahdavi, S., Bozorgmehr, B., Lachman, R. L., Mittaz-Crettol, L., Campos-Xavier, B., Nampoothiri, S., Unger, S., Rivolta, C., Levade, T., and Superti-Furga, A., “Brief Report: Peripheral Osteolysis in Adults Linked to ASAH1 (Acid Ceramidase) Mutations: A New Presentation of Farber's Disease.”, Arthritis Rheumatol, vol. 68, no. 9, pp. 2323-7, 2016.

Publisher : Arthritis Rheumatol

Year : 2015

Molecular Genetic Testing for Carrier-Prenatal Diagnosis and Computational Analysis of Oculocutaneous Albinism Type 1

Cite this Research Publication : K. Renugadevi, Mary, J. Asnet, Perumalsamy, V., Seshadri, S., Jagadeesh, S., Suresh, B., Dr. Sheela Nampoothiri, Shenbagarathai, R., Krishnaswamy, S., and Sundaresan, P., “Molecular Genetic Testing for Carrier-Prenatal Diagnosis and Computational Analysis of Oculocutaneous Albinism Type 1”, Genetic Disorders & Genetic Reports, vol. 2014, 2015.

Publisher : Genetic Disorders Genetic Reports

Year : 2014

Novel mutations in the glucocerebrosidase gene of Indian patients with Gaucher disease

Cite this Research Publication : C. Ankleshwaria, Mistri, M., Bavdekar, A., Muranjan, M., Dave, U., Tamhankar, P., Khanna, V., Jasinge, E., Dr. Sheela Nampoothiri, and Kadangot, S. Edayankara, “Novel mutations in the glucocerebrosidase gene of Indian patients with Gaucher disease”, Journal of human genetics, vol. 59, pp. 223–228, 2014.

Publisher : Journal of human genetics

Year : 2014

Imaging findings in a distinct lethal inherited arteriopathy syndrome associated with a novel mutation in the FBLN4 gene

Cite this Research Publication : Dr. Rajesh kannan, Dr. Mahesh K., Dr. Sheela Nampoothiri, Malfait, F., De Paepe, A., Moorthy, S., and , “Imaging findings in a distinct lethal inherited arteriopathy syndrome associated with a novel mutation in the FBLN4 gene”, European radiology, vol. 24, pp. 1742–1748, 2014.

Publisher : European radiology

Year : 2014

Expanding the spectrum of HEXA mutations in Indian patients with Tay–Sachs disease

Cite this Research Publication : J. Sheth, Mistri, M., Datar, C., Kalane, U., Patil, S., Kamate, M., Shah, H., Dr. Sheela Nampoothiri, Gupta, S., and Sheth, F., “Expanding the spectrum of HEXA mutations in Indian patients with Tay–Sachs disease”, Molecular Genetics and Metabolism Reports, vol. 1, pp. 425–430, 2014.

Publisher : Molecular Genetics and Metabolism Reports

Year : 2014

Clinical utility of multiplex ligation-dependent probe amplification technique in identification of aetiology of unexplained mental retardation: a study in 203 Indian patients

Cite this Research Publication : V. R. Boggula, Shukla, A., Danda, S., Hariharan, S. V., Dr. Sheela Nampoothiri, Kumar, R., Phadke, S. R., and , “Clinical utility of multiplex ligation-dependent probe amplification technique in identification of aetiology of unexplained mental retardation: a study in 203 Indian patients”, The Indian journal of medical research, vol. 139, p. 66, 2014.

Publisher : The Indian journal of medical research

Year : 2013

Michael Bjorn Petersen and Anne De Paepe, Helical mutations in type I collagen that affect the processing of the amino-propeptide result in an Osteogenesis Imperfecta/Ehlers-Danlos Syndrome overlap syndrome

Cite this Research Publication : F. Malfait, Symoens, S., Goemans, N., Gyftodimou, Y., Holmberg, E., López-González, V., Mortier, G., Nampoothiri, S., Petersen, M. Bjorn, and De Paepe, A., “Michael Bjorn Petersen and Anne De Paepe, Helical mutations in type I collagen that affect the processing of the amino-propeptide result in an Osteogenesis Imperfecta/Ehlers-Danlos Syndrome overlap syndrome”, Orphanet Journal of Rare Diseases, vol. 8, 2013.

Publisher : Orphanet Journal of Rare Diseases

Year : 2013

Ethnic-specific WRN mutations in South Asian Werner syndrome patients: potential founder effect in patients with Indian or Pakistani ancestry. Molecular Genetics & Genomic Medicine

Cite this Research Publication : B. Saha, Lessel, D., Nampoothiri, S., Rao, A. S., M, F., ,, Peter, D., Bennett, C., N€urnberg, G., N€urnberg, P., Martin, G. M., Kubisch, C., and Oshima, J., “Ethnic-specific WRN mutations in South Asian Werner syndrome patients: potential founder effect in patients with Indian or Pakistani ancestry. Molecular Genetics & Genomic Medicine”, Molecular Genetics & Genomic Medicine, pp. 7–14, 2013.

Publisher : Molecular Genetics & Genomic Medicine, p. 7–14

Year : 2012

Severe neurologic manifestations from cervical spine instability in spondylo-megaepiphyseal-metaphyseal dysplasia

Cite this Research Publication : Ma Simon, Campos-Xavier, A. Bb, Mittaz-Crettol, Lb, Valadares, E. Rc, Carvalho, Dd, Speck-Martins, C. Ed, Nampoothiri, Se, Alanay, Yf, Mihci, Eg, van Bever, Yh, Garcia-Segarra, Nb, Cavalcanti, Dh, Mortier, Gi, Bonafé, Lb, and Superti-Furga, Ab, “Severe neurologic manifestations from cervical spine instability in spondylo-megaepiphyseal-metaphyseal dysplasia”, American Journal of Medical Genetics, Part C: Seminars in Medical Genetics, vol. 160 C, pp. 230-237, 2012.

Publisher : American Journal of Medical Genetics, Part C: Seminars in Medical Genetics

Year : 2012

Novel KIF7 mutations extend the phenotypic spectrum of acrocallosal syndrome

Cite this Research Publication : Aab Putoux, Nampoothiri, Sc, Laurent, Nd, Cormier-Daire, Vab e, Beales, P. Lf, Schinze, Ag, Bartholdi, Dg, Alby, Cab h, Thomas, Se, Elkhartoufi, Ne, Ichkou, Ae, Litzler, Je, Munnich, Aab e, Encha-Razavi, Fab e, Kannan, Ri, Faivre, Ljk, Boddaert, Nbl, Rauch, Ag, Vekemans, Mab e, and Attié-Bitach, Tab e, “Novel KIF7 mutations extend the phenotypic spectrum of acrocallosal syndrome”, Journal of Medical Genetics, vol. 49, pp. 713-720, 2012.

Publisher : Journal of Medical Genetics

Year : 2012

Fanconi-bickel Syndrome

Cite this Research Publication : KaMohandas Nair, Sakamoto, Ob, Jagadeesh, Sc, and Nampoothiri, Sd, “Fanconi-bickel Syndrome”, Indian Journal of Pediatrics, vol. 79, pp. 112-114, 2012.

Publisher : Indian Journal of Pediatrics

Year : 2012

The diagnostic challenge of progressive pseudorheumatoid dysplasia (PPRD): A review of clinical features, radiographic features, and WISP3 mutations in 63 affected individuals

Cite this Research Publication : NaGarcia Segarra, Mittaz, La, Campos-Xavier, A. Ba, Bartels, C. Fb, Tuysuz, Bc, Alanay, Yd, Cimaz, Re, Cormier-Daire, Vf, Di Rocco, Mg, Duba, H. - Ch, Elcioglu, N. Hi, Forzano, Fj, Hospach, Tk, Kilic, El, Kuemmerle-Deschner, J. Bm, Mortier, Gn, Mrusek, So, Nampoothiri, Sp, Obersztyn, Eq, Pauli, R. Mr, Selicorni, As, Tenconi, Rt, Unger, Su, Utine, G. El, Wright, Mv, Zabel, Bw, Warman, M. Lx, Superti-Furga, Ay, and Bonafé, La, “The diagnostic challenge of progressive pseudorheumatoid dysplasia (PPRD): A review of clinical features, radiographic features, and WISP3 mutations in 63 affected individuals”, American Journal of Medical Genetics, Part C: Seminars in Medical Genetics, vol. 160 C, pp. 217-229, 2012.

Publisher : American Journal of Medical Genetics, Part C: Seminars in Medical Genetics

Year : 2012

Crigler-najjar syndrome type 2: Novel UGT1A1 mutation

Cite this Research Publication : Pa Lohse, Nair, Kb, and Nampoothiri, Sc, “Crigler-najjar syndrome type 2: Novel UGT1A1 mutation”, Indian Journal of Human Genetics, vol. 18, pp. 233-234, 2012.

Publisher : Indian Journal of Human Genetics

Year : 2012

Characterization of a distinct lethal arteriopathy syndrome in twenty-two infants associated with an identical, novel mutation in FBLN4 gene, confirms fibulin-4 as a critical determinant of human vascular elastogenesis

Cite this Research Publication : Mai Kappanayil, Nampoothiri, Sb, Kannan, Rc, Renard, Md, Coucke, Pd, Malfait, Fd, Menon, Se, Ravindran, H. Kf, Kurup, Rg, Faiyaz-Ul-Haque, Mh, Kumar, Ka, and De Paepe, Ad, “Characterization of a distinct lethal arteriopathy syndrome in twenty-two infants associated with an identical, novel mutation in FBLN4 gene, confirms fibulin-4 as a critical determinant of human vascular elastogenesis”, Orphanet Journal of Rare Diseases, vol. 7, 2012.

Publisher : Orphanet Journal of Rare Diseases

Year : 2012

Analysis of the WISP3 gene in Indian families with progressive pseudorheumatoid dysplasia

Cite this Research Publication : Aa Dalal, Bhavani, S. La, Togarrati, P. Pa, Bierhals, Tb, Nandineni, M. Rc, Danda, Sd, Danda, De, Shah, Hf, Vijayan, Sf, Gowrishankar, Kg, Phadke, S. Rh, Bidchol, A. Mi, Rao, A. Pj, Nampoothiri, Sk, Kutsche, Kb, and Girisha, K. Mi, “Analysis of the WISP3 gene in Indian families with progressive pseudorheumatoid dysplasia”, American Journal of Medical Genetics, Part A, vol. 158 A, pp. 2820-2828, 2012.

Publisher : American Journal of Medical Genetics, Part A

Year : 2012

3-M syndrome lead to disordered growth factor signaling

Cite this Research Publication : H. D, Murray, P. G., Coulson, T., Sud, A., Omokanye, A., Stratta, E., Sakhinia, F., Bonshek, C., Wilson, L. C., Wakeling, E., Temtamy, S. A., ,, ,, Mansour, S., Carcavill, A., Nampoothiri, S., Khan, W. I., Banerjee, I., Chandle, K. E., Black, G. C. M., and Clayton, P. E., “3-M syndrome lead to disordered growth factor signaling”, Journal of Molecular Endocrinology, pp. 267–275, 2012.

Publisher : Journal of Molecular Endocrinology

Year : 2011

Macrostomia, thin upper vermilion border, long philtrum, broad halluces, and intellectual disability in two sibs

Cite this Research Publication : Sa Nampoothiri, Kuthiroly, Sa, Fauth, Cb, Krabichler, Bb, Attie-Bitach, Tc, and Hennekam, R. Cd, “Macrostomia, thin upper vermilion border, long philtrum, broad halluces, and intellectual disability in two sibs”, American Journal of Medical Genetics, Part A, vol. 155, pp. 2465-2468, 2011.

Publisher : American Journal of Medical Genetics

Year : 2011

Lipoprotein lipase deficiency in an infant

Cite this Research Publication : Sa Nampoothiri, Radhakrishnan, Nb, Schwentek, Ac, and Hoffmann, M. Ma, “Lipoprotein lipase deficiency in an infant”, Indian Pediatrics, vol. 48, pp. 805-806, 2011.

Publisher : Indian Pediatrics

Year : 2011

Familial autosomal recessive renal tubular acidosis: Importance of early diagnosis

Cite this Research Publication : Aab Vivante, Lotan, Dc, Pode-Shakked, Nb, Landau, De, Svec, Pf, Nampoothiri, Sg, Verma, Ih, Abu-Libdeh, Ai, Bockenhauer, Dj, Dekel, Bab, and Anikster, Yd, “Familial autosomal recessive renal tubular acidosis: Importance of early diagnosis”, Nephron - Physiology, vol. 119, pp. p31-p39, 2011.

Publisher : Nephron - Physiology

Year : 2011

Congenital myotonic dystrophy with asymptomatic mother

Cite this Research Publication : K. Ma Anand, Biradar, V. Ma, Panicker, J. Nb, and Nampoothiri, Sc, “Congenital myotonic dystrophy with asymptomatic mother”, Indian Pediatrics, vol. 48, pp. 565-567, 2011.

Publisher : Indian Pediatrics

Year : 2011

Chondrodysplasia and abnormal joint development associated with mutations in IMPAD1, encoding the Golgi-resident nucleotide phosphatase, gPAPP

Cite this Research Publication : L. E. L. Ma Vissers, Lausch, Eb, Unger, Sbc, Campos-Xavier, A. Bd, Gilissen, Ca, Rossi, Ae, Del Rosario, Ma, Venselaar, Hf, Knoll, Ug, Nampoothiri, Sh, Nair, Mi, Spranger, Jb, Brunner, H. Ga, Bonafé, Ld, Veltman, J. Aa, Zabel, Bb, and Superti-Furga, Abd, “Chondrodysplasia and abnormal joint development associated with mutations in IMPAD1, encoding the Golgi-resident nucleotide phosphatase, gPAPP”, American Journal of Human Genetics, vol. 88, pp. 608-615, 2011.

Publisher : American Journal of Human Genetics

Year : 2011

Characterization of sSMC by FISH and molecular techniques

Cite this Research Publication : Fa Sheth, Andrieux, Jb, Ewers, Ec, Kosyakova, Nc, Weise, Ac, Sheth, Hd, Romana, S. - Pe, LeLorc'h, Me, Delobel, Bf, Theisen, Of, Liehr, Tc, Nampoothiri, Sg, and Sheth, Ja, “Characterization of sSMC by FISH and molecular techniques”, European Journal of Medical Genetics, vol. 54, pp. 247-255, 2011.

Publisher : European Journal of Medical Genetics

Year : 2011

Association of TALS developmental disorder with defect in minor splicing component U4atac snRNA

Cite this Research Publication : Pab Edery, Marcaillou, Cc, Sahbatou, Md, Labalme, Aa, Chastang, Ja, Touraine, Re, Tubacher, Ed, Senni, Fa, Bober, M. Bf, Nampoothiri, Sg, Jouk, P. - Shi, Steichen, Ej, Berland, Skl, Toutain, Amn, Wise, C. Ao, Sanlaville, Dab, Rousseau, Fc, Clerget-Darpoux, Fpq, and Leutenegger, A. - Lrs, “Association of TALS developmental disorder with defect in minor splicing component U4atac snRNA”, Science, vol. 332, pp. 240-243, 2011.

Publisher : Science

Year : 2011

Analysis of mutations and recombination activity in RAG-deficient patients

Cite this Research Publication : Ea Asai, Wada, Ta, Sakakibara, Ya, Toga, Aa, Toma, Ta, Shimizu, Tb, Nampoothiri, Sc, Imai, Kd, Nonoyama, Sd, Morio, Te, Muramatsu, Hf, Kamachi, Yf, Ohara, Og, and Yachie, Aa, “Analysis of mutations and recombination activity in RAG-deficient patients”, Clinical Immunology, vol. 138, pp. 172-177, 2011.

Publisher : Clinical Immunology

Year : 2010

Phenotypic features of carbohydrate sulfotransferase 3 (CHST3) deficiency in 24 patients: Congenital dislocations and vertebral changes as principal diagnostic features

Cite this Research Publication : Sab Unger, Lausch, Ea, Rossi, Ac, Mégarbané, Ad, Sillence, De, Alcausin, Me, Aytes, Af, Mendoza-Londono, Rg, Nampoothiri, Sh, Afroze, Bi, Hall, Bj, Lo, I. Fk, Lam, S. Tl, Hoefele, Jm, Rost, Im, Wakeling, En, Mangold, Eo, Godbole, Kp, Vatanavicharn, Nq, Franco, L. Mr, Chandler, Ks, Hollander, Sa, Velten, Ta, Reicherter, Ka, Spranger, Ja, Robertson, St, Bonafé, Lu, Zabel, Bab, and Superti-Furga, Aa, “Phenotypic features of carbohydrate sulfotransferase 3 (CHST3) deficiency in 24 patients: Congenital dislocations and vertebral changes as principal diagnostic features”, American Journal of Medical Genetics, Part A, vol. 152 A, pp. 2543-2549, 2010.

Publisher : American Journal of Medical Genetics, Part A

Year : 2010

Phenotype and natural history in Marshall-Smith syndrome

Cite this Research Publication : A. Ca Shaw, Van Balkom, I. Dbc, Bauer, Md, Cole, T. Re, Delrue, Mf, Van Haeringen, Ag, Holmberg, Eh, Knight, S. Ji, Mortier, Gj, Nampoothiri, Sk, Pušeljić, Sl, Zenker, Mm, Cormier-Daire, Vn, and Hennekam, R. Co, “Phenotype and natural history in Marshall-Smith syndrome”, American Journal of Medical Genetics, Part A, vol. 152, pp. 2714-2726, 2010.

Publisher : American Journal of Medical Genetics

Year : 2010

Musculocontractural Ehlers-Danlos Syndrome (former EDS type VIB) and adducted thumb clubfoot syndrome (ATCS) represent a single clinical entity caused by mutations in the dermatan-4-sulfotransferase 1 encoding CHST14 gene

Cite this Research Publication : Fa Malfait, Syx, Da, Vlummens, Pa, Symoens, Sa, Nampoothiri, Sb, Hermanns-Lê, Tc, Van Laer, La, and De Paepe, Aa, “Musculocontractural Ehlers-Danlos Syndrome (former EDS type VIB) and adducted thumb clubfoot syndrome (ATCS) represent a single clinical entity caused by mutations in the dermatan-4-sulfotransferase 1 encoding CHST14 gene”, Human Mutation, vol. 31, pp. 1233-1239, 2010.

Publisher : Human Mutation

Year : 2010

An Indian family with Sjögren-Larsson syndrome caused by a novel ALDH3A2 mutation

Cite this Research Publication : Ka Sakai, Akiyama, Ma, Yanagi, Ta, Nampoothiri, Sb, Mampilly, Tc, Sunitha, Vb, and Shimizu, Ha, “An Indian family with Sjögren-Larsson syndrome caused by a novel ALDH3A2 mutation”, International Journal of Dermatology, vol. 49, pp. 1031-1033, 2010.

Publisher : International Journal of Dermatology

Year : 2010

Distinct effects of allelic NFIX mutations on nonsense-mediated mRNA decay engender either a sotos-like or a Marshall-Smith Syndrome

Cite this Research Publication : Va Malan, Rajan, Db, Thomas, Sa, Shaw, A. Cc, Picard, HaLouis Dit, Layet, Vd, Till, Me, Van Haeringen, Af, Mortier, Gg, Nampoothiri, Sh, Pušeljić, Si, Legeai-Mallet, La, Carter, N. Pb, Vekemans, Ma, Munnich, Aa, Hennekam, R. Cj, Colleaux, La, and Cormier-Daire, Va, “Distinct effects of allelic NFIX mutations on nonsense-mediated mRNA decay engender either a sotos-like or a Marshall-Smith Syndrome”, American Journal of Human Genetics, vol. 87, pp. 189-198, 2010.

Publisher : American Journal of Human Genetics

Year : 2005

Copper Replacement Treatment for Symptomatic Menkes Disease: Ethical Considerations

Cite this Research Publication : Sheela AR, Kaler SG, Liu P, Lem K, Latha M., "Copper Replacement Treatment for Symptomatic Menkes Disease: Ethical Considerations," Clinical Genetics, 2005:68:278-283.

Publisher : Clinical Genetics

Year : 2005

Acrodysostosis: Autosomal Dominant Transmission

Cite this Research Publication : Sheela S. R., Ajai P., Thomas G., "Acrodysostosis: Autosomal Dominant Transmission," Indian Pediatrics, 2005; 42:822-826.

Publisher : Indian Pediatrics

Year : 2004

Griscelli Syndrome

Cite this Research Publication : Sheela SR, Latha M, Susy JI, "Griscelli syndrome," Indian Pediatrics 2004; 41:944-947.

Publisher : Indian Pediatrics

Year : 2000

Narcotic poisoning in an infant

Cite this Research Publication : Sheela SR. "Narcotic poisoning in an infant," Indian Journal of Practical Pediatrics, 2000; 2(27): 185-186.

Publisher : Indian Journal of Practical Pediatrics

Year : 2000

Myotonia Congenita: Response to Carbamazepine

Cite this Research Publication : Sheela SR., "Myotonia Congenita: Response to Carbamazepine," Indian Pediatrics, 2000; 37: 1122- 1125.

Publisher : Indian Pediatrics

Year : 2000

An unusual case of Lightning injury

Cite this Research Publication : Sheela SR, Kattakkayam MM, Borappa K. "An unusual case of Lightning injury." Indian Pediatrics, 2000; 37: 802 - 803

Publisher : Indian Pediatrics

Year : 1999

Cornelia De Lange Syndrome: Discordance in twins

Cite this Research Publication : Sheela SR. "Cornelia De Lange Syndrome: Discordance in twins." Indian Pediatr 1999; 36: 1267-1270.

Publisher : Indian Pediatrics

Book Chapter

Year : 2001

Lightning Injury

Cite this Research Publication : Sheela SR. "Lightning Injury," in: Santhosh Kumar A. Manual of pediatric practice. 1st ed. Hyderabad: Paras Publishing; 2001.p 101 -102.

Publisher : Paras Publishing

Area of Interest
  • Children with genetic & chromosomal problems.
  • Children with neurodevelopmental regression.
  • Parents of children with genetic problems who wish to have another baby.
  • Children with skeletal dysplasias.
Achievements
  • Dr. D. S. Munagekar National IMA Award for the year 2013 – 2014.

  • Dr. Eapen Samuel Memorial Award for the Best Research Paper published in 2014.

  • Awardee of Commonwealth Scholarship- 2004-2005 for MSc. Medical Genetics, University of Glasgow.

  • Reviewer of two International journals – Pediatrics International & Journal of Pediatrics Infectious Diseases.

  • Attended 13th International Maple Syrup Urine Disease symposium in Ohio, USA in June 15 -17th 2006.

  • Presented Grand rounds in Children’s Hospital, New Orleans, USA on June 21st 2005.

  • First prize for free paper presentation at Pedicon South 1999 at Calicut, on November 14th 1999.

  • Coordinator for National Neonatology forum Quiz in Neonatology for Postgraduates at Kochi, 2002.

  • First prize for free paper presentation at International Pediatric Neurology Conference at Trivandrum, on April 7th 2002.

  • Winner of 6th Practicing Pediatricians quiz at State round at Cochin, on October 6th 2002.

  • Winner of 6th Practicing Pediatricians quiz at South Zone round at Kottayam, on October 19th 2002.

  • First Prize at Final round of 6th Practicing Pediatricians quiz at National level at Mumbai, on Pedicon 2003 at January 5th 2003.

  • Life member of Indian Academy of Pediatrics from January 1st 1995.

  • Life member of Indian Academy of Pediatrics, Kerala State branch.

  • Life member of Hematology Oncology Chapter of Indian Academy of Pediatrics from April 19th 1999.

Admissions Apply Now