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Dr. Saiprabha V. N.

Assistant Professor, Department of Pharmaceutical Chemistry & Analysis, School of Pharmacy, Kochi

Qualification: B. Pharm., M. Pharm., Ph.D

Bio

Dr. Saiprabha V. N. currently serves as an Assistant Professor in the Department of Pharmaceutical Chemistry & Analysis, Amrita School of Pharmacy, Kochi, India. She obtained her M. Pharm. in Pharmaceutical Chemistry from Mahatma Gandhi University, Kottayam, Kerala, India, in 2013 and Ph. D. in Pharmaceutical Chemistry from Rajiv Gandhi University of Health Sciences, Bengaluru, India, in 2020. Dr. Saiprabha’s primary areas of focus are in drug design and synthesis especially in the area of cancer and molecular modelling. Her main research interest includes the design and synthesis of Bromodomain inhibitors.

Publications

Journal Article

Year : 2019

Design of Chalcones of 7-Azaindole as Raf-B Inhibitors

Cite this Research Publication : D. Giles, Dr. Saiprabha N, and Yeshna, G., “Design of Chalcones of 7-Azaindole as Raf-B Inhibitors”, Journal of Advanced Chemical Sciences, vol. 4, pp. 606-608, 2019.

Publisher : Journal of Advanced Chemical Sciences

Year : 2019

Azaindole containing heterocyclic derivatives with pyrimidine scaffolds as potent bromodomain 4 inhibitors

Cite this Research Publication : Dr. Saiprabha N, D, G., and UR, S., “Azaindole containing heterocyclic derivatives with pyrimidine scaffolds as potent bromodomain 4 inhibitors ”, International Journal of Pharmacy and Pharmaceutical Science, 2019.

Publisher : International Journal of Pharmacy and Pharmaceutical Science

Year : 2019

Exploring 7-Azaindole Containing Heterocyclic Derivatives with Pyrimidine Scaffolds as Potent Bromodomain 4 Inhibitors-An In-Silico Approach

Cite this Research Publication : Dr. Saiprabha N, Giles, D., and UR, S., “Exploring 7-Azaindole Containing Heterocyclic Derivatives with Pyrimidine Scaffolds as Potent Bromodomain 4 Inhibitors-An In-Silico Approach”, International Journal of Pharmacy and Pharmaceutical Science , 2019.

Publisher : International Journal of Pharmacy and Pharmaceutical Science

Year : 2018

Azaindole Derivatives as COX-2 Inhibitors: An In-silico Approach

Cite this Research Publication : D. Giles and Dr. Saiprabha N, “Azaindole Derivatives as COX-2 Inhibitors: An In-silico Approach.”, Asian Journal of Organic Medicine Chemistry , vol. 3(2), 2018.

Publisher : Asian Journal of Organic Medicine Chemistry

Year : 2015

Pyrimidine Derivatives as Dual Inhibitors of COX-2 and STAT-3 as Potential Anticancer and Anti-Inflammatory Agents – An In Silico Approach

Cite this Research Publication : Dr. Saiprabha N, Giles, D., Swamy, gurubasavaraja, and Chaudhary, A., “Pyrimidine Derivatives as Dual Inhibitors of COX-2 and STAT-3 as Potential Anticancer and Anti-Inflammatory Agents – An In Silico Approach”, International Journal of Pharmacy and Pharmaceutical Sciences, vol. 3, pp. 1-25, 2015.

Publisher : International Journal of Pharmacy and Pharmaceutical Sciences

Year : 2015

Design of COX-2 inhibitors– An In-silico Approach.

Cite this Research Publication : D. Giles, Dr. Saiprabha N, and PM, G. Basavaraja, “Design of COX-2 inhibitors– An In-silico Approach.”, International Journal of Pharmacy and Pharmaceutical Science, vol. 7, no. 9, 2015.

Publisher : International Journal of Pharmacy and Pharmaceutical Science

Year : 2014

Preliminary phytochemical screening and antioxidant activity of petroleum-ether and hydroalcoholic extracts of the leaves of strobilanthes barbatus

Cite this Research Publication : Dr. Saiprabha N, “Preliminary phytochemical screening and antioxidant activity of petroleum-ether and hydroalcoholic extracts of the leaves of strobilanthes barbatus”, American Journal of Pharmtech Research, vol. 4, pp. 318-325, 2014.

Publisher : American Journal of Pharmtech Research

Patents

Year : 2021

Novel pyrimidine derivatives as potent anti-inflammatory and anti-cancer agents

Cite this Research Publication : Dr. Saiprabha N, “Novel pyrimidine derivatives as potent anti-inflammatory and anti-cancer agents”, U.S. Patent Application No. 201741026833 A.2021.

Publisher : U.S. Patent, Application No. 201741026833 A.

Education 
YEAR DEGREE/PROGRAM INSTITUTION
2014 – 2019 Ph.D. in Pharmaceutical Chemistry
Thesis Title
: “Design, Synthesis and Structural Activity Relationship Studies of Novel Pyrimidine Derivatives As Potent Anti-inflammatory And Anticancer Agents.”
Rajiv Gandhi University of Health Sciences, Karnataka, India.
2011 – 2013 M.Pharm. in Pharmaceutical Chemistry M. G University, Kottayam, Kerala, India.
2006 – 2010 B.Pharm. Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.

Expertise in Drug Design Softwares: Accelerys Drug Discovery Studio, Torch, AutoDock

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