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Dr. Sabitha M.

Principal

Dr. Sabitha M. currently serves as Principal at the School of Pharmacy, Health Science Campus, Kochi. She was conferred with a Ph. D. in Pharmaceutical Sciences from Amrita Vishwa Vidyapeetham University in 2012.

Qualification: Ph.D
sabitham@aims.amrita.edu
Research Interest: Development of Wound Dressings, Nanolipid Carrier Based Brain Drug Delivery, Novel Approaches for Effective Topical Delivery, Novel Formulation Approaches to Reinvent Drugs of Potential Therapeutic Benefit

Bio

Dr. Sabitha M. joined Amrita School of Pharmacy in March 2000. She completed her Bachelor’s Degree in Pharmacy from St. John’s Pharmacy college, Bangalore University and her Master’s Degree in Pharmaceutics from the department of Pharmaceutical Sciences, Doctor Hari Singh Gour Vishwavidyalaya, Sagar, (Formerly known as Saugor University, SAGAR) of Madhya Pradesh which is a pioneer Pharmaceutical institution. She completed her Ph.D in Pharmaceutical Sciences from Amrita Vishwa Vidyapeetham University in 2012. Her doctoral dissertation was titled “Chitin Nanogels as an Effective Nanocarrier for the Treatment of Melanoma via the Transdermal Route”. She served as the Vice Principal of the School during the period February 2008 – September 2011. She has more than 17 years of teaching and research experience and has several publications in national and international journals.

During July-August 2010, she received one-month advanced training in the practice of clinical pharmacy at the University of Michigan, College of Pharmacy, United States. Dr. Sabitha’s current research focuses on nanolipid carrier based brain drug delivery and novel approaches for effective topical delivery. Other areas of interest include development of wound dressings, novel formulation approaches to reinvent drugs of potential therapeutic benefit etc.

Publications

Journal Article

Year : 2020

Stimuli-Responsive Polymeric Nanosystem for Colon Specific Drug Delivery

Authors : Dr. Sabitha M., Sreeja C. Nair, Joseph, Sharon Kunnath

Publisher : Adv Pharm Bull, Tabriz University of Medical Sciences

S. Kunnath Joseph, Dr. Sabitha M., and Sreeja C. Nair, “Stimuli-Responsive Polymeric Nanosystem for Colon Specific Drug Delivery”, Adv Pharm Bull, vol. 10, no. 1, pp. 1-12, 2020.

Year : 2020

Kaempferol-Mediated Sensitization Enhances Chemotherapeutic Efficacy of Sorafenib Against Hepatocellular Carcinoma: An in Silico and in Vitro Approach

Authors : Dr. Sabitha M., Nair, Bhagyalakshmi; Anto, Ruby John; Lekshmi R Nath

Publisher : Adv Pharm Bull, Tabriz University of Medical Sciences

B. Nair, Anto, R. John, Dr. Sabitha M., and Lekshmi R Nath, “Kaempferol-Mediated Sensitization Enhances Chemotherapeutic Efficacy of Sorafenib Against Hepatocellular Carcinoma: An in Silico and in Vitro Approach”, Adv Pharm Bull, vol. 10, no. 3, pp. 472-476, 2020.

Year : 2019

Nanotechnology Approaches for Enhanced CNS Delivery in Treating Alzheimer’s Disease

Authors : Dr. Sabitha M., Dr. Krishnakumar Menon, M.A. Arya; Maneesha Kalappurackal; Dr. Sabitha M.; Sreeja C. Nair

Publisher : Journal of Drug Delivery Science and Technology

M. A. Arya, Maneesha Kalappurackal, Dr. Sabitha M., Krishnakumar N. Menon, and Sreeja C. Nair, “Nanotechnology Approaches for Enhanced CNS Delivery in Treating Alzheimer's Disease”, Journal of Drug Delivery Science and Technology, vol. 51, pp. 297 - 309, 2019.

Year : 2019

Novel Aspirin Controlled Release Nanomedicine Suppresses Platelet Aggregation: Implications for Extending the Golden Hour in Stroke (Under review)

Authors : Dr. Sabitha M., Dr. Kaladhar Kamalasanan, R., J.

Publisher : Pharmaceutical Research

Dr. Kaladhar Kamalasanan, R., J., and Dr. Sabitha M., “Novel aspirin controlled release nanomedicine suppresses platelet aggregation: implications for extending the golden hour in stroke (Under review)”, Pharmaceutical Research, 2019.

Year : 2019

Omega-3 fatty acid based nanolipid formulation of atorvastatin for treating hyperlipidemia

Authors : Dr. Sabitha M., Sreedhar, R.; Kumar, V.S.; Bhaskaran Pillai, A.K

Publisher : Advanced Pharmaceutical Bulletin

R. Sreedhar, Kumar, V. S., Pillai, A. K. Bhaskaran, and Dr. Sabitha M., “Omega-3 fatty acid based nanolipid formulation of atorvastatin for treating hyperlipidemia”, Advanced Pharmaceutical Bulletin, vol. 9, pp. 271-280, 2019.

Year : 2019

Brinzolamide-2-hydroxypropyl beta cyclodextrin complex loaded chitosan nanogel for ocular drug delivery

Authors : Dr. Sabitha M., Swati Gupta, D. V. Pillai, Swati P. Gupta

Publisher : Advanced Scientific Research

D. V. Pillai, Dr. Sabitha M., and Swati P. Gupta, “Brinzolamide-2-hydroxypropyl beta cyclodextrin complex loaded chitosan nanogel for ocular drug delivery”, International Journal of Pharmaceutical Research, vol. 11, pp. 350-362, 2019.

Year : 2019

Chaulmoogra oil based Methotrexate Loaded Topical Nanoemulsion for the Treatment of Psoriasis

Authors : Dr. Sabitha M., Dr. Jayakumar Rangasamy, P. Rajitha, Shammika, P., S. Aiswarya, Gopikrishnan, A

Publisher : Journal of Drug Delivery Science and Technology

P. Rajitha, Shammika, P., S. Aiswarya, Gopikrishnan, A., Dr. Jayakumar Rangasamy, and Dr. Sabitha M., “Chaulmoogra oil based Methotrexate Loaded Topical Nanoemulsion for the Treatment of Psoriasis”, Journal of Drug Delivery Science and Technology, vol. 49, pp. 463 - 476, 2019.

Year : 2018

Guargum and Eudragit ® coated curcumin liquid solid tablets for colon specific drug delivery.

Authors : Dr. Sabitha M., S Kumar, Vrinda; Rijo, John;

Publisher : Int J Biol Macromol

V. S. Kumar, Rijo, J., and M, S., “Guargum and Eudragit ® coated curcumin liquid solid tablets for colon specific drug delivery.”, International Journal of Biological Macromolecules, vol. 110, pp. 318-327, 2018.

Year : 2017

Comparative Anti-psoriatic Efficacy Studies of Clobetasol Loaded Chitin Nanogel and Marketed Cream

Authors : Dr. Sabitha M., Panonnummal, Rajitha; Jayakumar, R;

Publisher : Eur J Pharm Sci

R. Panonnummal, Jayakumar, R., and Sabitha, M., “Comparative anti-psoriatic efficacy studies of clobetasol loaded chitin nanogel and marketed cream.”, Eur J Pharm Sci, vol. 96, pp. 193-206, 2017.

Year : 2016

Skin and muscle permeating antibacterial nanoparticles for treating Staphylococcus aureus infected wounds

Authors : Dr. Sabitha M., Dr. Raja Biswas, Dr. Jayakumar Rangasamy, V. Dhanalakshmi, Nimal, T. R.

Publisher : John Wiley and Sons Inc

V. Dhanalakshmi, Nimal, T. R., Dr. Sabitha M., Dr. Raja Biswas, and Dr. Jayakumar Rangasamy, “Skin and muscle permeating antibacterial nanoparticles for treating Staphylococcus aureus infected wounds”, Journal of Biomedical Materials Research - Part B Applied Biomaterials, 2016

Year : 2016

Chitosan-eudragit Magnetic Microspheres of Sulfasalazine for Colon Drug Delivery

Authors : Dr. Sabitha M., Thamburu Sasidharan; Shammika.P; Sreeja C. Nair.

Publisher : International Journal of Pharmaceutical Sciences Review and Research.

T. Sasidharan, .P, S., Dr. Sabitha M., and Sreeja C. Nair, “Chitosan-eudragit Magnetic Microspheres of Sulfasalazine for Colon Drug Delivery”, International Journal of Pharmaceutical Sciences Review and Research, vol. 41, no. 2, pp. 125-131, 2016.

Year : 2016

Chitosan nanoparticles in drug therapy of infectious and inflammatory diseases

Authors : Dr. Sabitha M., Dr. Jayakumar Rangasamy, Dr. Raja Biswas, Dr. Rajitha Panonnummal, Gopinath, D

Publisher : Expert Opinion on Drug Delivery, Taylor and Francis Ltd

Rajitha Panonnummal, Gopinath, D., Dr. Raja Biswas, Dr. Sabitha M., and Dr. Jayakumar Rangasamy, “Chitosan nanoparticles in drug therapy of infectious and inflammatory diseases”, Expert Opinion on Drug Delivery, vol. 13, no. 8, pp. 1177-1194, 2016

Year : 2015

Nanogels for Delivery, Imaging and Therapy

Authors : Dr. Sabitha M., Dr. Jayakumar Rangasamy, Dr. Rajitha Panonnummal, A. J. Sivaram, Maya, S.

Publisher : Wiley-Blackwell


A. J. Sivaram, Rajitha Panonnummal, Maya, S., Dr. Jayakumar Rangasamy, and Dr. Sabitha M., “Nanogels for Delivery, Imaging and Therapy”, Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2015

Year : 2014

Synthesis, Characterization and Biological Activities of Curcumin Nanospheres

Authors : Dr. Sabitha M., Dr. Jayakumar Rangasamy, Dr. Raja Biswas, T. R. Arunraj, Rejinold, N. S., Mangalathillam, S., Saroj, S

Publisher : Journal of Biomedical Nanotechnology

T. R. Arunraj, Rejinold, N. S., Mangalathillam, S., Saroj, S., Dr. Raja Biswas, Dr. Jayakumar Rangasamy, and Dr. Sabitha M., “Synthesis, Characterization and Biological Activities of Curcumin Nanospheres”, Journal of Biomedical Nanotechnology, vol. 10, pp. 238-250, 2014

Year : 2013

Structural model of the alpha phosphoglucomutase: A promising target for the treatment of mycobacterium tuberculosis

Authors : Dr. Sabitha M., M. Mukesh, M Prathap

Publisher : International Journal of Pharmacy and Pharmaceutical Sciences.

M. Mukesh, M Prathap, M., and Dr. Sabitha M., “Structural model of the alpha phosphoglucomutase: A promising target for the treatment of mycobacterium tuberculosis”, International Journal of Pharmacy and Pharmaceutical Sciences., vol. 5, no. 2, pp. 107-114, 2013

Year : 2013

Fluconazole Loaded Chitin Nanogels as a Topical Ocular Drug Delivery Agent for Corneal Fungal Infections

Authors : Dr. Raja Biswas, Dr. Jayakumar Rangasamy, Dr. Sabitha M., N. Mohammed, N. Rejinold, S., Mangalathillam, S.

Publisher : Journal of Biomedical Nanotechnology

N. Mohammed, N. Rejinold, S., Mangalathillam, S., Dr. Raja Biswas, Nair, S. V., Dr. Jayakumar Rangasamy, and Dr. Sabitha M., “Fluconazole Loaded Chitin Nanogels as a Topical Ocular Drug Delivery Agent for Corneal Fungal Infections”, Journal of Biomedical Nanotechnology, vol. 9, pp. 1521-1531, 2013

Year : 2013

Development and Evaluation of 5-fluorouracil Loaded Chitin Nanogels for Treatment of Skin Cancer

Authors : Dr. Sabitha M., Dr. Jayakumar Rangasamy, N. Rejinold, S., Nair, A., Lakshmanan, V. - K., Nair, S. V

Publisher : Carbohydrate Polymers

Dr. Sabitha M., N. Rejinold, S., Nair, A., Lakshmanan, V. - K., Nair, S. V., and Dr. Jayakumar Rangasamy, “Development and Evaluation of 5-fluorouracil Loaded Chitin Nanogels for Treatment of Skin Cancer”, Carbohydrate Polymers, vol. 91, pp. 48-51, 2013.

Year : 2013

Curcumin Nanospheres by Surfactant Free Wet Milling Method (In Press)

Authors : Dr. Sabitha M., Dr. Jayakumar Rangasamy, Prof. Shantikumar Nair, T. R. Anuraj, N Rejinold, S., Biswas, R., Saroj, S., Shantikumar V Nair

Publisher : Journal of Biomedical Nanotechnology

T. R. Anuraj, N Rejinold, S., Biswas, R., Saroj, S., Shantikumar V Nair, Dr. Jayakumar Rangasamy, and Dr. Sabitha M., “Curcumin Nanospheres by Surfactant Free Wet Milling Method (In Press)”, Journal of Biomedical Nanotechnology, 2013.

Year : 2012

Current trends in lipid based delivery systems and its applications in drug delivery

Authors : Dr. Sabitha M., S. Saroj, Baby, D. A

Publisher : Asian Journal of Pharmaceutical and Clinical Research

S. Saroj, Baby, D. A., and Dr. Sabitha M., “Current trends in lipid based delivery systems and its applications in drug delivery”, Asian Journal of Pharmaceutical and Clinical Research, vol. 5, pp. 4-9, 2012

Year : 2012

Curcumin Loaded Chitin Nanogels for Skin Cancer Treatment via the Transdermal Route

Authors : Dr. Jayakumar Rangasamy, Dr. Sabitha M., Prof. Shantikumar Nair, S. Mangalathillam, Rejinold, N. S., Nair, A., Lakshmanan, V. - K., Shantikumar V Nair

Publisher : Nanoscale


S. Mangalathillam, Rejinold, N. S., Nair, A., Lakshmanan, V. - K., Shantikumar V Nair, Dr. Jayakumar Rangasamy, and Dr. Sabitha M., “Curcumin Loaded Chitin Nanogels for Skin Cancer Treatment via the Transdermal Route”, Nanoscale, vol. 4, pp. 239-250, 2012

Year : 2012

Synthesis, Characterization and in vitro Cytocompatibility Studies of Chitin Nanogels for Biomedical Applications

Authors : Dr. Sabitha M., Dr. Jayakumar Rangasamy, S. N. Rejinold, Nair, A., Chennazhi, K. P., Tamura, H., Nair, S. V

Publisher : Carbohydrate Polymers

S. N. Rejinold, Nair, A., Dr. Sabitha M., Chennazhi, K. P., Tamura, H., Nair, S. V., and Dr. Jayakumar Rangasamy, “Synthesis, Characterization and in vitro Cytocompatibility Studies of Chitin Nanogels for Biomedical Applications”, Carbohydrate Polymers, vol. 87, pp. 943 - 949, 2012

Year : 2012

Nanotechnology in cosmetics: Opportunities and challenges

Authors : Dr. Sabitha M., S. Raj, Jose, S., Sumod, U. S

Publisher : Journal of Pharmacy and Bioallied Sciences


S. Raj, Jose, S., Sumod, U. S., and Dr. Sabitha M., “Nanotechnology in cosmetics: Opportunities and challenges”, Journal of Pharmacy and Bioallied Sciences, vol. 4, pp. 186-193, 2012

Year : 2012

Mechanism of solubility of liquisolid formulation in non volatile solvent: A review

Authors : Dr. Sabitha M., D. Aa Baby, Saroj, S

Publisher : International Journal of Pharmacy and Pharmaceutical Sciences

D. Aa Baby, Saroj, Sa, and Dr. Sabitha M., “Mechanism of solubility of liquisolid formulation in non volatile solvent: A review”, International Journal of Pharmacy and Pharmaceutical Sciences, vol. 4, pp. 710-715, 2012

Year : 2009

Radio Frequency Identification: An Effective Tool to Prevent Drug Counterfeiting

Authors : Dr. Sabitha M., Dr. Aneesh T. P., Dr. Subin Mary Zachariah, M, S. Sekhar

Publisher : Journal of Pharmacy Research

Dr. Aneesh T. P., M, S. Sekhar, P.O, S., Dr. Sabitha M., and Dr. Subin Mary Zachariah, “Radio Frequency Identification: An Effective Tool to Prevent Drug Counterfeiting”, Journal of Pharmacy Research, vol. 2, no. 4, pp. 678 - 679, 2009.

Year : 2003

Development and Characterization of Transdermal Drug Delivery Systems for Diltiazem Hydrochloride

Authors : Dr. Sabitha M., S. K. Jain, Chourasia, M., Jain, R., Jain, A. K., Ashawat, M., and Jha, A. K

Publisher : Drug delivery

S. K. Jain, Chourasia, M., Dr. Sabitha M., Jain, R., Jain, A. K., Ashawat, M., and Jha, A. K., “Development and Characterization of Transdermal Drug Delivery Systems for Diltiazem Hydrochloride”, Drug delivery, vol. 10, pp. 169-77, 2003

Year : 2003

Radiopharmaceuticals: Preparation, evaluation and applications(Review).

Authors : Dr. Sabitha M., M. K. Chourasia, Ashawat, M. S., Jain, N., Chalasani, K. B., Jain, R. K., Jain, A. K

Publisher : Indian Journal of Pharmaceutical Sciences.


M. K. Chourasia, Ashawat, M. S., Jain, N., Chalasani, K. B., Jain, R. K., Jain, A. K., Dr. Sabitha M., and S.K., J., “Radiopharmaceuticals: Preparation, evaluation and applications(Review). ”, Indian Journal of Pharmaceutical Sciences. , vol. 65, no. 5, pp. 439-449., 2003.

Year : 2003

Nanomedicine: Promise Of The Future In Disease Management

Authors : Dr. Sabitha M., Dr. Aneesh T. P., S. M. Sonal, Prabhakar, V

Publisher : The Internet Journal of Nanotechnology


S. M. Sonal, Prabhakar, V., Dr. Aneesh T. P., and Dr. Sabitha M., “Nanomedicine: Promise Of The Future In Disease Management”, The Internet Journal of Nanotechnology, vol. 2, 2003.

Patents

Year : 2011

The art, method, manner, process and system of preparation of curcumin loaded chitin nanogels for skin penetration

Authors : Dr. Sabitha M., Dr. Jayakumar Rangasamy, Prof. Shantikumar Nair, Shantikumar V Nair, Amrita, N., N Rejinold, S., and Lakshmanan, V. Kumar

Publisher : Amrita Vishwa Vidyapeetham

Dr. Sabitha M., Dr. Jayakumar Rangasamy, Shantikumar V Nair, Amrita, N., N Rejinold, S., and Lakshmanan, V. Kumar, “The art, method, manner, process and system of preparation of curcumin loaded chitin nanogels for skin penetration”, U.S. Patent 2353/CHE/2011 A2011.

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