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Dr. Raja Biswas

Professor, Amrita School for Nanosciences and Molecular Medicine, Kochi

Qualification: Ph.D
rajabiswas@aims.amrita.edu
Google Scholar Profile

Bio

Dr. Raja Biswas is a Professor at Infectious Diseases Group, Amrita Center for Nanosciences and Molecular Medicine (ACNSMM). He joined Amrita in June 2009. He has completed his Ph. D. and post doctoral work in the field of Microbial Genetics and Infectious Diseases from the Department of Microbial Genetics, University of Tuebingen, Germany.

He is the recipient of Ramalingaswami fellowship, Rapid Grant for Young Scientists from Department of Biotechnology in 2009 and Fast track grant for young scientists from Department of science and technology in 2010. He has to his credit nearly 106 publications in reputed journals like Molecular Microbiology, Journal of Bacteriology, Infection & Immunity and Journal of Biological Chemistry.

Dr. Biswas heads the infectious diseases laboratory at Amrita and his research is focused on understanding more about the mechanism of infectious diseases specifically in understanding the complex network of host-microbe interactions, pathogenic mechanisms to escape the surveillance of host immune system and mechanisms for drug resistance.

 

Publications

Journal Article

Year : 2022

Superhydrophilic multifunctional nanotextured titanium dental implants: in vivo short and long-term response in a porcine model

Cite this Research Publication : Mathew, A., Abraham, S., Stephen, S., Babu A.S., Gowd S.G., Vinod V., Biswas R., Nair, M.B., Unni, A.K.K., Menon, D. Superhydrophilic Multifunctional Nanotextured Titanium Dental Implants: In vivo Short and Long-Term Response in a Porcine Model (2022) Biomaterials Science, 10, 728-743.

Publisher : Biomaterials Science

Year : 2021

Dirofilarial adult worms can also dance.

Cite this Research Publication : Dr. Anil Kumar V., Aswin Prabhakaran, Sanju Sherji, Dr. Lalitha Biswas, Arya Ramachandran, Mohan Abraham, and Dr. Raja Biswas, “Dirofilarial adult worms can also dance.”, Clinical Microbiology and Infection, vol. 27, pp. 1118-1119., 2021.

Publisher : Clinical Microbiology and Infection,

Year : 2021

Therapeutic applications of lysostaphin against Staphylococcus aureus

Cite this Research Publication : J. Jayakumar, V.A. Kumar, L. Biswas,R. Biswas "Therapeutic applications of lysostaphin against Staphylococcus aureus" in Journal Appl Microbiol, 2021.

Publisher : Journal of Applied Microbiology,

Year : 2021

Comparison of Phenotypic MRSA Detection Methods with PCR for mecA Gene in the Background of Emergence of Oxacillin-Susceptible MRSA

Cite this Research Publication : Deepa Nair, Nandita Shashindran, Anil Kumar, Vivek Vinodh, Lalitha Biswas, and Raja Biswas "Comparison of Phenotypic MRSA Detection Methods with PCR for mecA Gene in the Background of Emergence of Oxacillin-Susceptible MRSA", Microbial Drug Resistance, 2021

Publisher : Microbial Drug Resistance,

Year : 2021

Epidemiology of Nontuberculous Mycobacterial Infection in Tuberculosis Suspects

Cite this Research Publication : Parasmal Suresh, Anil Kumar, Raja Biswas, Divya Vijayakumar, Swathy Thulasidharan, Gopikrishnan Anjaneyan, Akhilesh Kunoor, and Lalitha Biswas "Epidemiology of Nontuberculous Mycobacterial Infection in Tuberculosis Suspects", American Journal Tropical Medicine and Hygiene. 2021;105(5):1335–8

Publisher : American Journal Tropical Medicine and Hygiene,

Year : 2021

Prevalence of high-risk HPV and its genotypes-Implications in the choice of prophylactic HPV vaccine.

Cite this Research Publication : Alka Suresh, Parasmal Suresh, Dr. Raja Biswas, Anupama Rajanbabu, Sarala Sreedhar, and Dr. Lalitha Biswas, “Prevalence of high-risk HPV and its genotypes-Implications in the choice of prophylactic HPV vaccine.”, J Med Virol, vol. 93, no. 8, pp. 5188-5192, 2021.

Publisher : J Med Virol

Year : 2021

Antifungal activity of Syzygium samarangense leaf extracts against Candida.

Cite this Research Publication : S Raj, V Vinod, J Jayakumar, P Suresh, Dr. Anil Kumar V., and Dr. Raja Biswas, “Antifungal activity of Syzygium samarangense leaf extracts against Candida.”, Letters in Applied Microbiology, vol. 73, no. 1, pp. 31-38, 2021.

Publisher : Letters in Applied Microbiology

Year : 2021

Candidatus Dirofilaria Hongkongensis Infections in Humans During 2005 to 2020, in Kerala, India.

Cite this Research Publication : Dr. Anil Kumar V., Ani Sreedhar, Dr. Lalitha Biswas, Sarga Prabhat, Parasmal Suresh, Asokan, A., Rita Mary Tomy, Vivek Vinod, Bindu Lakshmanan, Ajit Nambiar, and Dr. Raja Biswas, “Candidatus Dirofilaria Hongkongensis Infections in Humans During 2005 to 2020, in Kerala, India.”, American Journal of Tropical Medicine and Hygiene, vol. 104, pp. 2046-2049., 2021.

Publisher : American Journal of Tropical Medicine and Hygiene

Year : 2021

Comparison of Phenotypic MRSA Detection Methods with PCR for Gene in the Background of Emergence of Oxacillin-Susceptible MRSA.

Cite this Research Publication : Deepa Nair, Nandita Shashindran, Anil kumar, Vivek Vinodh, Dr. Lalitha Biswas, and Dr. Raja Biswas, “Comparison of Phenotypic MRSA Detection Methods with PCR for Gene in the Background of Emergence of Oxacillin-Susceptible MRSA.”, Microbial Drug Resistance, vol. 27, no. 9, pp. 1190-1194, 2021.

Publisher : Microbial Drug Resistance

Year : 2021

Protective efficacy of Alum adjuvanted Amidase protein vaccine against Staphylococcus aureus infection in multiple mouse models.

Cite this Research Publication : M. K. Suresh, Vasudevan, A. K., Dr. Lalitha Biswas, and Dr. Raja Biswas, “Protective efficacy of Alum adjuvanted Amidase protein vaccine against Staphylococcus aureus infection in multiple mouse models.”, Journal of Applied Microbiology (Article in Press), 2021.

Publisher : Journal of Applied Microbiology

Year : 2021

Development and evaluation of plumbagin loaded chitin hydrogel for the treatment of skin cancer

Cite this Research Publication : Akanksha Nair, Sreeja C. Nair, Asoke Banerji, Dr. Raja Biswas, and Ullas Mony, “Development and evaluation of plumbagin loaded chitin hydrogel for the treatment of skin cancer”, Journal of Drug Delivery Science and Technology, vol. 66, p. 102804, 2021.

Publisher : Journal of Drug Delivery Science and Technology

Year : 2021

Therapeutic applications of lysostaphin against Staphylococcus aureus

Cite this Research Publication : J. Jayashree, Kumar, V. A., Lalitha Biswas, and Dr. Raja Biswas, “Therapeutic applications of lysostaphin against Staphylococcus aureus”, Journal of Applied Microbiology, vol. n/a, 2021.

Publisher : Journal of Applied Microbiology

Year : 2021

Improving Diagnosis of Hepatitis C Virus Infection Using Hepatitis C Core Antigen Testing in a Resource-Poor Setting.

Cite this Research Publication : Ayswarya Kannan, Dr. Lalitha Biswas, Anil Kumar, Jessy Kurian, Anjaly S. Nair, Parasmal Suresh, Shine Sadasivan, and Dr. Raja Biswas, “Improving Diagnosis of Hepatitis C Virus Infection Using Hepatitis C Core Antigen Testing in a Resource-Poor Setting.”, Rev Soc Bras Med Trop, vol. 54, p. e02532020, 2021.

Publisher : Rev Soc Bras Med Trop

Year : 2021

Interaction mechanism of Mycobacterium tuberculosis GroEL2 protein with macrophage Lectin-like, oxidized low-density lipoprotein receptor-1: An integrated computational and experimental study.

Cite this Research Publication : V. Vinod, Pushkaran, A. Choorakott, Anil Kumar, Dr. Gopi Mohan C., and Dr. Raja Biswas, “Interaction mechanism of Mycobacterium tuberculosis GroEL2 protein with macrophage Lectin-like, oxidized low-density lipoprotein receptor-1: An integrated computational and experimental study.”, Biochim Biophys Acta Gen Subj, vol. 1865, no. 1, p. 129758, 2021.

Publisher : Biochim Biophys Acta Gen Subj

Year : 2020

BCG Infection due to MPT64 – Negative Strain: A Diagnostic Challenge

Cite this Research Publication : Parasmal Suresh, Lalitha Biswas, Vinitha Prasad, Anil Kumar, Suchitra Sivadas, Sadia Khan, and Raja Biswas "BCG Infection due to MPT64-Negative Strain: A Diagnostic Challenge", American Journal of Tropical Medicine Hygiene, 2020

Year : 2020

The cell surface adhesins of Mycobacterium tuberculosis

Cite this Research Publication : Vivek Vinoda, Sukhitha sri Vijayrajratnam, Anil Kumar Vasudevan, Raja Biswas "The cell surface adhesins of Mycobacterium tuberculosis", Microbiological Research, February 2020

Publisher : Microbiological Research

Year : 2020

BCG Infection due to MPT64-Negative Strain: A Diagnostic Challenge.

Cite this Research Publication : Parasmal Suresh, Lalitha Biswas, Prasad, V., Anil Kumar, Sivadas, S., Khan, S., and Dr. Raja Biswas, “BCG Infection due to MPT64-Negative Strain: A Diagnostic Challenge.”, The American Journal of Tropical Medicine and Hygeine, 2020 Sep 103(3):1072-1075

Publisher : The American Journal of Tropical Medicine and Hygeine

Year : 2020

Biodegradable nanocomposite fibrous scaffold mediated local delivery of vancomycin for the treatment of MRSA infected experimental osteomyelitis.

Cite this Research Publication : Krishnan Amit G, Dr. Raja Biswas, Dr. Deepthy Menon, and Dr. Manitha B. Nair, “Biodegradable nanocomposite fibrous scaffold mediated local delivery of vancomycin for the treatment of MRSA infected experimental osteomyelitis.”, Biomater Sci, vol. 8, no. 9, pp. 2653-2665, 2020.

Publisher : Biomater Sci

Year : 2019

Combination of Repurposed Drug Diosmin with Amoxicillin-Clavulanic acid Causes Synergistic Inhibition of Mycobacterial Growth

Cite this Research Publication : A. Choorakott Pushkaran, Vinod, V., Muralidharan Vanuopadath, Sudarslal S, Shantikumar V Nair, Vasudevan, A. Kumar, Dr. Raja Biswas, and Dr. Gopi Mohan C., “Combination of Repurposed Drug Diosmin with Amoxicillin-Clavulanic acid Causes Synergistic Inhibition of Mycobacterial Growth”, Scientific Reports, vol. 9, no. 1, 2019.

Publisher : Scientific Reports, Nature Publishing Group,

Year : 2019

Species distribution and antifungal susceptibility among clinical isolates of Candida parapsilosis complex from India

Cite this Research Publication : S. Maria, Barnwal, G., Anil Kumar, Mohan, K., Vinod, V., Varghese, A., and Dr. Raja Biswas, “Species Distribution and Antifungal Susceptibility Among Clinical Isolates of Candida Parapsilosis Complex from India”, Rev Iberoam Micol, pp. 147-150, 2018.

Publisher : Rev Iberoam Micol

Year : 2019

Antistaphylococcal and Neutrophil Chemotactic Injectable κ-Carrageenan Hydrogel for Infectious Wound Healing

Cite this Research Publication : Shiva Muthuswamy, Aparna Viswanathan, Ramanathan Yegappan, Vignesh Selvaprithiviraj, Anil Kumar Vasudevan, Raja Biswas, and Rangasamy Jayakumar "Antistaphylococcal and Neutrophil Chemotactic Injectable κ-Carrageenan Hydrogel for Infectious Wound Healing", ACS Appl Bio Mater, 2019

Publisher : ACS Appl Bio Mater,

Year : 2019

Reconsidering Azithromycin Disc Diffusion Interpretive Criteria for in View of Azithromycin MIC Creep Among Typhoidal and Nontyphoidal Salmonella

Cite this Research Publication : S. Khan, Kurup, P., Vinod, V., Dr. Raja Biswas, Pillai, G. Krishna, and Anil Kumar, “Reconsidering Azithromycin Disc Diffusion Interpretive Criteria for in View of Azithromycin MIC Creep Among Typhoidal and Nontyphoidal Salmonella”, J Lab Physicians, vol. 11, no. 1, pp. 39-44, 2019.

Publisher : J Lab Physicians

Year : 2018, 2019

An update on recent developments in the prevention and treatment of Staphylococcus aureus biofilms

Cite this Research Publication : M. K. Suresh, Dr. Raja Biswas, and Lalitha Biswas, “An Update on Recent Developments in the Prevention and Treatment of Staphylococcus Aureus Biofilms”, International Journal of Medical Microbiology, vol. 309, pp. 1-12, 2019.

Publisher : International Journal of Medical Microbiology

Year : 2019

Development of Mangifera indica leaf extract incorporated carbopol hydrogel and its antibacterial efficacy against Staphylococcus aureus

Cite this Research Publication : R. Bright Chirayath, A, A. Viswanatha, Dr. Jayakumar Rangasamy, Dr. Raja Biswas, and Vijayachandran, L. Sumitra, “Development of Mangifera indica Leaf Extract Incorporated Carbopol Hydrogel and its Antibacterial Efficacy Against Staphylococcus Aureus”, Colloids Surf B Biointerfaces, vol. 178, pp. 377-384, 2019.

Publisher : Colloids Surf B Biointerfaces,

Year : 2018

Synthesis, Characterisation and Biomedical Applications of Curcumin Conjugated Chitosan Microspheres.

Cite this Research Publication : T. S. Saranya, Rajan, V. K., Biswas, R., Dr. Jayakumar Rangasamy, and Sathianarayanan, S., “Synthesis, Characterisation and Biomedical Applications of Curcumin Conjugated Chitosan Microspheres.”, Int J Biol Macromol, vol. 110, pp. 227-233, 2018.

Publisher : International Journal of Biological Macromolecules, Elsevier B.V.

Year : 2018

Colistin resistance due to insertional inactivation of the mgrB in Klebsiella pneumoniae of clinical origin: First report from India

Cite this Research Publication : Anil Kumar, Lalitha Biswas, Neha Omgy, Karthika Mohan, Vivek Vinod, Anjali Sajeev, Prem Nair, Sanjeev Singh, and Raja Biswas "Colistin resistance due to insertional inactivation of the mgrB in Klebsiella pneumoniae of clinical origin: First report from India", Rev Esp Quimioter, 2018

Year : 2018, 2019

An update on recent developments in the prevention and treatment of Staphylococcus aureus biofilms

Cite this Research Publication : M. K. Suresh, Dr. Raja Biswas, and Lalitha Biswas, “An Update on Recent Developments in the Prevention and Treatment of Staphylococcus Aureus Biofilms”, International Journal of Medical Microbiology, vol. 309, pp. 1-12, 2019.

Publisher : International Journal of Medical Microbiology

Year : 2018

Structure-function Studies of Prothrombin Amrita, a Dysfunctional Prothrombin Characterized by Point Mutation at Arg553 → Gln

Cite this Research Publication : A. R. Melge, Prakash, O., S, S., Dr. Raja Biswas, Lalitha Biswas, and Dr. Gopi Mohan C., “Structure-Function Studies of Prothrombin Amrita, a Dysfunctional Prothrombin Characterized by Point Mutation at Arg553 → Gln”, International Journal of Biological Macromolecules, 2018.

Publisher : International Journal of Biological Macromolecules

Year : 2018

Chitosan Based Metallic Nanocomposite Scaffolds as Antimicrobial Wound Dressings

Cite this Research Publication : A. Mohandas, Deepthi, S., Dr. Raja Biswas, and Dr. Jayakumar Rangasamy, “Chitosan Based Metallic Nanocomposite Scaffolds as Antimicrobial Wound Dressings”, Bioactive Materials, vol. 3, pp. 267 - 277, 2018.

Publisher : Bioactive Materials

Year : 2018

Biological macromolecules based targeted nanodrug delivery systems for the treatment of intracellular infections

Cite this Research Publication : V. Aparna, Shiva, M., Dr. Raja Biswas, and Dr. Jayakumar Rangasamy, “Biological Macromolecules based Targeted Nanodrug Delivery Systems for the Treatment of Intracellular Infections”, Int J Biol Macromol, vol. 110, pp. 2-6, 2018.

Publisher : International Journal of Biological Macromolecules

Year : 2018

Autolysin Mediated Adherence of Staphylococcus Aureus with Fibronectin, Gelatin and Heparin.

Cite this Research Publication : C. Porayath, M. K. Suresh, Dr. Raja Biswas, Dr. Bipin G. Nair, Dr. Nandita Mishra, and Dr. Sanjay Pal, “Autolysin mediated adherence of Staphylococcus aureus with Fibronectin, Gelatin and Heparin.”, International Journal of Biological Macromolecules, vol. 110, pp. 179-184, 2018.

Publisher : International Journal of Biological Macromolecules

Year : 2017

Bacterial peptidoglycan with amidated meso-diaminopimelic acid evades NOD1 recognition: an insight into NOD1 structure–recognition

Cite this Research Publication : Sukhithasri Vijayrajratnam, Anju Choorakottayil Pushkaran, Aathira Balakrishnan, Anil Kumar Vasudevan, Raja Biswas, Chethampadi Gopi Mohan "Bacterial peptidoglycan with amidated meso-diaminopimelic acid evades NOD1 recognition: an insight into NOD1 structure–recognition", Biochemical Journal, 2017

Publisher : Biochemical Journal,

Year : 2017

Understanding the Molecular Differential Recognition of Muramyl Peptide Ligands by LRR Domains of Human NOD Receptors.

Cite this Research Publication : S. Vijayrajratnam, Pushkaran, A. Choorakott, Balakrishnan, A., Vasudevan, A. Kumar, Dr. Raja Biswas, and Dr. Gopi Mohan C., “Understanding the Molecular Differential Recognition of Muramyl Peptide Ligands by LRR Domains of Human NOD Receptors.”, Biochem J, vol. 474, no. 16, pp. 2691-2711, 2017.

Publisher : Biochem J

Year : 2017

Understanding the Adhesion Mechanism of Mucin Binding domain from Lactobacillus fermentum and its Role in Enteropathogen Exclusion.

Cite this Research Publication : M. Chatterjee, Pushkaran, A. Choorakott, Vasudevan, A. Kumar, Krishnakumar N. Menon, Dr. Raja Biswas, and Dr. Gopi Mohan C., “Understanding the Adhesion Mechanism of Mucin Binding domain from Lactobacillus fermentum and its Role in Enteropathogen Exclusion.”, Int J Biol Macromol, vol. 110, pp. 598-607, 2017.

Publisher : Int J Biol Macromol

Year : 2017

Mechanistic Understanding of Phenyllactic Acid Mediated Inhibition of Quorum Sensing and Biofilm Development in Pseudomonas Aeruginosa

Cite this Research Publication : M. Chatterjee, D'Morris, S., Paul, V., Warrier, S., Vasudevan, A. Kumar, Muralidharan Vanuopadath, Nair, S. Sadasivan, Dr. Bindhu Paul, Dr. Gopi Mohan C., and Dr. Raja Biswas, “Mechanistic Understanding of Phenyllactic Acid Mediated Inhibition of Quorum Sensing and Biofilm Development in Pseudomonas Aeruginosa”, Appl Microbiol Biotechnol, vol. 101, no. 22, pp. 8223-8236, 2017

Publisher : Appl Microbiol Biotechnol

Year : 2017

Impact of Cell Wall Peptidoglycan O-acetylation on the Pathogenesis of Staphylococcus Aureus in Septic Arthritis

Cite this Research Publication : G. Baranwal, Mohammad, M., Jarneborn, A., Reddy, B. Raghunath, Golla, A., Chakravarty, S., Biswas, L., Götz, F., Dr. Sahadev Shankarappa, Jin, T., and Dr. Raja Biswas, “Impact of Cell Wall Peptidoglycan O-acetylation on the Pathogenesis of Staphylococcus Aureus in Septic Arthritis”, Int J Med Microbiol, vol. 307, no. 7, pp. 388-397, 2017.

Publisher : Int J Med Microbiol

Year : 2017

Antibacterial and cytocompatible nanotextured Ti surface incorporating silver via single step hydrothermal processing

Cite this Research Publication : A. Mohandas, Krishnan, A. G., Dr. Raja Biswas, Dr. Deepthy Menon, and Dr. Manitha B. Nair, “Antibacterial and cytocompatible nanotextured Ti surface incorporating silver via single step hydrothermal processing”, Materials Science and Engineering C, vol. 75, pp. 115-124, 2017.

Publisher : Materials Science and Engineering C

Year : 2016

Faecal carriage rate of extended-spectrum β-lactamase-producing Enterobacteriaceae in hospitalised patients and healthy asymptomatic individuals coming for health check-up.

Cite this Research Publication : R. Babu, Kumar, A., Karim, S., Warrier, S., Nair, S. G., Singh, S. K., and Biswas, R., “Faecal carriage rate of extended-spectrum β-lactamase-producing Enterobacteriaceae in hospitalised patients and healthy asymptomatic individuals coming for health check-up.”, J Glob Antimicrob Resist, vol. 6, pp. 150-153, 2016.

Publisher : J Glob Antimicrob Resist,

Year : 2016

Antibiotic Resistance in Pseudomonas Aeruginosa and Alternative Therapeutic Options

Cite this Research Publication : M. Chatterjee, Anju, C. P., Biswas, L., V. Kumar, A., Dr. Gopi Mohan C., and Dr. Raja Biswas, “Antibiotic Resistance in Pseudomonas Aeruginosa and Alternative Therapeutic Options”, International Journal of Medical Microbiology, vol. 306, pp. 48 - 58, 2016.

Publisher : International Journal of Medical Microbiology, Elsevier GmbH,

Year : 2016

Faecal carriage rate of extended-spectrum β-lactamase-producing Enterobacteriaceae in hospitalised patients and healthy asymptomatic individuals coming for health check-up

Cite this Research Publication : Rachana Babu, Anil Kumar, Shamsul Karim, Sruthi Warrier, Suresh G. Nair, Sanjeev K. Singh, Raja Biswas "Faecal carriage rate of extended-spectrum β-lactamase-producing Enterobacteriaceae in hospitalised patients and healthy asymptomatic individuals coming for health check-up", Journal of Global Antimicrobial Resistance, 2016

Publisher : Journal of Global Antimicrobial Resistance.

Year : 2016

Antimicrobial Activity of Plumbagin, a Naturally Occurring Naphthoquinone from Plumbago Rosea, against Staphylococcus Aureus and Candida Albicans

Cite this Research Publication : Sweatha V. Nair, Baranwal, G., Chatterjee, M., Sachu, A., Dr. Anil Kumar V., Chinchu Bose, Dr. Asoke Banerji, and Dr. Raja Biswas, “Antimicrobial Activity of Plumbagin, a Naturally Occurring Naphthoquinone from Plumbago Rosea, against Staphylococcus Aureus and Candida Albicans”, International Journal of Medical Microbiology, vol. 306, pp. 237-248, 2016.

Publisher : International Journal of Medical Microbiology

Year : 2016

Skin and muscle permeating antibacterial nanoparticles for treating Staphylococcus aureus infected wounds

Cite this Research Publication : V. Dhanalakshmi, Nimal, T. R., Dr. Sabitha M., Dr. Raja Biswas, and Dr. Jayakumar Rangasamy, “Skin and muscle permeating antibacterial nanoparticles for treating Staphylococcus aureus infected wounds”, Journal of Biomedical Materials Research - Part B Applied Biomaterials, 2016

Publisher : John Wiley and Sons Inc

Year : 2016

Recent Developments in Drug-eluting Dressings for the Treatment of Chronic Wounds

Cite this Research Publication : R. Vilangattu Kunjikuttan, Jayasree, A., Biswas, R., and Jayakumar, R., “Recent developments in drug-eluting dressings for the treatment of chronic wounds.”, Expert Opin Drug Deliv, vol. 13, no. 12, pp. 1645-1647, 2016.

Publisher : Expert Opin Drug Deliv.

Year : 2016

Bacterial Peptidoglycan with Amidated Meso-diaminopimelic Acid Evades NOD1 Recognition: an Insight into NOD1 Structure-Recognition.

Cite this Research Publication : Sukhithasri Vijayrajratnam, Anju Choorakottayil Pushkaran, Aathira Balakrishnan, Anil Kumar Vasudevan, Raja Biswas, Chethampadi Gopi Mohan "Bacterial peptidoglycan with amidated meso-diaminopimelic acid evades NOD1 recognition: an insight into NOD1 structure–recognition", Biochemical Journal, 2017

Publisher : Biochem J.

Year : 2016

Anti-staphylococcal Activity of Injectable Nano Tigecycline/Chitosan-PRP Composite Hydrogel Using Drosophila melanogaster Model for Infectious Wounds

Cite this Research Publication : T. R. Nimal, Baranwal, G., Bavya, M. C., Dr. Raja Biswas, and Dr. Jayakumar Rangasamy, “Anti-staphylococcal Activity of Injectable Nano Tigecycline/Chitosan-PRP Composite Hydrogel Using Drosophila melanogaster Model for Infectious Wounds”, ACS Applied Materials and Interfaces, vol. 8, pp. 22074-22083, 2016.

Publisher : ACS Applied Materials and Interfaces, American Chemical Society.

Year : 2015

Evaluation of antibacterial activity and cytocompatibility of ciprofloxacin loaded gelatin-hydroxyapatite scaffolds as a local drug delivery system for osteomyelitis treatment

Cite this Research Publication : A. G. Krishnan, Jayaram, L., Dr. Raja Biswas, and Dr. Manitha B. Nair, “Evaluation of antibacterial activity and cytocompatibility of ciprofloxacin loaded gelatin-hydroxyapatite scaffolds as a local drug delivery system for osteomyelitis treatment”, Tissue Engineering - Part A, vol. 21, pp. 1422-1431, 2015.

Publisher : Tissue Engineering - Part A, Mary Ann Liebert Inc.,

Year : 2015

Understanding the Structure–Function Relationship of Lysozyme Resistance in Staphylococcus aureus by Peptidoglycan O-Acetylation Using Molecular Docking, Dynamics, and Lysis Assay

Cite this Research Publication : A. C. Pushkaran, Nataraj, N., Nair, N., Götz, F., Dr. Raja Biswas, and Dr. Gopi Mohan C., “Understanding the Structure–Function Relationship of Lysozyme Resistance in Staphylococcus aureus by Peptidoglycan O-Acetylation Using Molecular Docking, Dynamics, and Lysis Assay”, Journal of Chemical Information and Modeling, vol. 55, pp. 760-770, 2015.

Publisher : Journal of Chemical Information and Modeling

Year : 2015

Drug Loaded Bi-layered Sponge for Wound Management in Hyperfibrinolytic Conditions

Cite this Research Publication : A. Mohandas, Nimal, T. R., Das, V., Dr. Sahadev Shankarappa, Dr. Raja Biswas, and Dr. Jayakumar Rangasamy, “Drug Loaded Bi-layered Sponge for Wound Management in Hyperfibrinolytic Conditions”, Journal of Materials Chemistry B, vol. 3, pp. 5795-5805, 2015.

Publisher : Journal of Materials Chemistry B, Royal Society of Chemistry,

Year : 2015

Delivery of rifampicin-chitin nanoparticles into the intracellular compartment of polymorphonuclear leukocytes

Cite this Research Publication : K. T. Smitha, Nisha, N., Maya, S., Dr. Raja Biswas, and Dr. Jayakumar Rangasamy, “Delivery of rifampicin-chitin nanoparticles into the intracellular compartment of polymorphonuclear leukocytes”, International Journal of Biological Macromolecules, vol. 74, pp. 36 - 43, 2015.

Publisher : International Journal of Biological Macromolecules

Year : 2015

Comparative Efficacy of Chloramphenicol Loaded Chondroitin Sulfate and Dextran Sulfate Nanoparticles to Treat Intracellular Salmonella Infections

Cite this Research Publication : V. Kiruthika, Maya, S., Suresh, M. K., V. Kumar, A., Dr. Jayakumar Rangasamy, and Dr. Raja Biswas, “Comparative Efficacy of Chloramphenicol Loaded Chondroitin Sulfate and Dextran Sulfate Nanoparticles to Treat Intracellular Salmonella Infections”, Colloids and Surfaces B: Biointerfaces, vol. 127, pp. 33-40, 2015.

Publisher : Colloids and Surfaces B: Biointerfaces

Year : 2015

Amidase, a Cell Wall Hydrolase, Elicits Protective Immunity Against Staphylococcus Aureus and S. Epidermidis

Cite this Research Publication : N. Nair, Vinod, V., Suresh, M. K., Vijayrajratnam, S., Dr. Lalitha Biswas, Peethambaran, R., Vasudevan, A. K., and Dr. Raja Biswas, “Amidase, a Cell Wall Hydrolase, Elicits Protective Immunity Against Staphylococcus Aureus and S. Epidermidis”, International Journal of Biological Macromolecules, vol. 77, pp. 314-321, 2015.

Publisher : International Journal of Biological Macromolecules, Elsevier

Year : 2014

Tetracycline Nanoparticles Loaded Calcium Sulfate Composite Beads for Periodontal Management

Cite this Research Publication : S. N. Reddy, Sowmya Srinivasan, Bumgardner, J. D., Chennazhi, K. P., Dr. Raja Biswas, and Dr. Jayakumar Rangasamy, “Tetracycline Nanoparticles Loaded Calcium Sulfate Composite Beads for Periodontal Management”, Biochimica et Biophysica Acta - General Subjects, vol. 1840, pp. 2080-2090, 2014.

Publisher : Biochimica et Biophysica Acta - General Subjects

Year : 2014

Synthesis, Characterization and Biological Activities of Curcumin Nanospheres

Cite this Research Publication : T. R. Arunraj, Rejinold, N. S., Mangalathillam, S., Saroj, S., Dr. Raja Biswas, Dr. Jayakumar Rangasamy, and Dr. Sabitha M., “Synthesis, Characterization and Biological Activities of Curcumin Nanospheres”, Journal of Biomedical Nanotechnology, vol. 10, pp. 238-250, 2014

Publisher : Journal of Biomedical Nanotechnology

Year : 2014

Synthesis and Anti-Staphylococcal Activity of TiO2 Nanoparticles and Nanowires in Ex Vivo Porcine Skin Model

Cite this Research Publication : N. Nataraj, Anjusree, G. S., Madhavan, A. Anish, Priyanka, P., Sankar, D., Nisha, N., Dr. Lakshmi Sumitra, Dr. Jayakumar Rangasamy, Balakrishnan, A., and Dr. Raja Biswas, “Synthesis and Anti-Staphylococcal Activity of TiO2 Nanoparticles and Nanowires in Ex Vivo Porcine Skin Model”, Journal of Biomedical Nanotechnology, vol. 10, pp. 864-870, 2014.

Publisher : Journal of Biomedical Nanotechnology

Year : 2014

Staphylococcus aureus in polymicrobial infections: impact on pathogenesis

Cite this Research Publication : N. Nair, Dr. Raja Biswas, Götz, F., and Biswas, L., “Staphylococcus aureus in polymicrobial infections: impact on pathogenesis”, Infection and Immunity, p. IAI–00059, 2014.

Publisher : Infection and Immunity, American Society for Microbiology,

Year : 2014

Mycobacterium tuberculosis treatment modalities and recent insights

Cite this Research Publication : V. Sukhithasri, Vinod, V., Varma, S., and Dr. Raja Biswas, “Mycobacterium tuberculosis treatment modalities and recent insights”, Current drug delivery, vol. 11, pp. 744–752, 2014.

Publisher : Current drug delivery, Bentham Science Publishers

Year : 2014

Multifaceted Chitin/poly (lactic-co-glycolic) Acid Composite Nanogels

Cite this Research Publication : S. N Rejinold, Dr. Raja Biswas, Chellan, G., and Dr. Jayakumar Rangasamy, “Multifaceted Chitin/poly (lactic-co-glycolic) Acid Composite Nanogels”, International journal of biological macromolecules, vol. 67, pp. 279–288, 2014.

Publisher : International journal of biological macromolecules

Year : 2014

Antimicrobial drugs encapsulated in fibrin nanoparticles for treating microbial infested wounds

Cite this Research Publication : B. M. Alphonsa, Kumar, P. T. Sudheesh, Praveen, G., Dr. Raja Biswas, Chennazhi, K. P., and Dr. Jayakumar Rangasamy, “Antimicrobial drugs encapsulated in fibrin nanoparticles for treating microbial infested wounds”, Pharmaceutical Research, vol. 31, pp. 1338-1351, 2014.

Publisher : Pharmaceutical Research, Springer New York LLC.

Year : 2014

Amidase encapsulated O-carboxymethyl chitosan nanoparticles for vaccine delivery

Cite this Research Publication : K. T. Smitha, Sreelakshmi, M., Nisha, N., Dr. Jayakumar Rangasamy, and Dr. Raja Biswas, “Amidase encapsulated O-carboxymethyl chitosan nanoparticles for vaccine delivery”, International Journal of Biological Macromolecules, vol. 63, pp. 154-157, 2014.

Publisher : International Journal of Biological Macromolecules

Year : 2013

Preparation of chitin nanogels containing nickel nanoparticles

Cite this Research Publication : A. N. Kumar, N. Rejinold, S., Anjali, P., Balakrishnan, A., Dr. Raja Biswas, and Dr. Jayakumar Rangasamy, “Preparation of chitin nanogels containing nickel nanoparticles”, Carbohydrate Polymers, vol. 97, pp. 469-474, 2013.

Publisher : Carbohydrate Polymers

Year : 2013

Molecular defect of ‘Prothrombin Amrita’: Substitution of arginine by glutamine (Arg553 to Gln) near the Na+ binding loop of prothrombin

Cite this Research Publication : S. Sivasundar, Oommen, A. T., Prakash, O., Baskaran, S., Dr. Raja Biswas, Nair, S., Dr. Gopi Mohan C., and Lalitha Biswas, “Molecular defect of 'Prothrombin Amrita': Substitution of arginine by glutamine (Arg553 to Gln) near the Na+ binding loop of prothrombin”, Blood Cells, Molecules, and Diseases, vol. 50, pp. 182-183, 2013.

Publisher : Blood Cells, Molecules, and Diseases

Year : 2013

Molecular characterization of methicillin-resistant staphylococcus aureus causing fatal purulent pericarditis

Cite this Research Publication : V. Anil Kumar, Nair, N., Thachathodiyl, R., Nandakumar, A., Dinesh, K. R., Thatcher, E., Karim, S., and Dr. Raja Biswas, “Molecular characterization of methicillin-resistant staphylococcus aureus causing fatal purulent pericarditis”, Journal of laboratory physicians, vol. 5, p. 136, 2013.

Publisher : Journal of laboratory physicians

Year : 2013

Innate immune recognition of microbial cell wall components and microbial strategies to evade such recognitions

Cite this Research Publication : Va Sukhithasri, Nisha, Na, Dr. Lalitha Biswas, Kumar, VbAnil, and Dr. Raja Biswas, “Innate immune recognition of microbial cell wall components and microbial strategies to evade such recognitions”, Microbiological Research, vol. 168, pp. 396-406, 2013.

Publisher : Microbiological Research

Year : 2013

Fluconazole Loaded Chitin Nanogels as a Topical Ocular Drug Delivery Agent for Corneal Fungal Infections

Cite this Research Publication : N. Mohammed, N. Rejinold, S., Mangalathillam, S., Dr. Raja Biswas, Nair, S. V., Dr. Jayakumar Rangasamy, and Dr. Sabitha M., “Fluconazole Loaded Chitin Nanogels as a Topical Ocular Drug Delivery Agent for Corneal Fungal Infections”, Journal of Biomedical Nanotechnology, vol. 9, pp. 1521-1531, 2013

Publisher : Journal of Biomedical Nanotechnology

Year : 2013

Evaluation of Wound Healing Potential of β-chitin Hydrogel/nano zinc Oxide Composite Bandage

Cite this Research Publication : P. T. Sudheesh Kumar, Lakshmanan, V. - K., Raj, M., Dr. Raja Biswas, Hiroshi, T., Nair, S. V., and Dr. Jayakumar Rangasamy, “Evaluation of Wound Healing Potential of β-chitin Hydrogel/nano zinc Oxide Composite Bandage”, Pharmaceutical Research, vol. 30, pp. 523-537, 2013.

Publisher : Pharmaceutical Research

Year : 2013

Detection of oxacillin-susceptible mecA-positive Staphylococcus aureus isolates by use of chromogenic medium MRSA ID

Cite this Research Publication : V. Aa Kumar, Steffy, Ka, Chatterjee, Mb, Sugumar, Mc, Dinesh, K. Ra, Manoharan, Ac, Karim, Sa, and Dr. Raja Biswas, “Detection of oxacillin-susceptible mecA-positive Staphylococcus aureus isolates by use of chromogenic medium MRSA ID”, Journal of Clinical Microbiology, vol. 51, pp. 318-319, 2013.

Publisher : Journal of Clinical Microbiology

Year : 2013

Chitosan-hyaluronic acid/nano silver composite sponges for drug resistant bacteria infected diabetic wounds

Cite this Research Publication : B. S. Anisha, Dr. Raja Biswas, Chennazhi, K. P., and Dr. Jayakumar Rangasamy, “Chitosan-hyaluronic acid/nano silver composite sponges for drug resistant bacteria infected diabetic wounds”, International Journal of Biological Macromolecules, vol. 62, pp. 310-320, 2013.

Publisher : International Journal of Biological Macromolecules

Year : 2012

Synthesis and biological evaluation of chitin hydrogel/nano ZnO composite bandage as antibacterial wound dressing

Cite this Research Publication : P. T. S. Kumar, Lakshmanan, V. - K., Dr. Raja Biswas, Nair, S. V., and Dr. Jayakumar Rangasamy, “Synthesis and biological evaluation of chitin hydrogel/nano ZnO composite bandage as antibacterial wound dressing”, Journal of Biomedical Nanotechnology, vol. 8, pp. 891-900, 2012.

Publisher : Journal of Biomedical Nanotechnology

Year : 2012

Proton-binding capacity of Staphylococcus aureus wall teichoic acid and its role in controlling autolysin activity

Cite this Research Publication : Dr. Raja Biswas, Martinez, R. E., Göhring, N., Schlag, M., Josten, M., Xia, G., Hegler, F., Gekeler, C., Gleske, A. - K., Götz, F., and , “Proton-binding capacity of Staphylococcus aureus wall teichoic acid and its role in controlling autolysin activity”, PloS one, vol. 7, p. e41415, 2012.

Publisher : Public Library of Science

Year : 2012

Efficacy of tetracycline encapsulated O-carboxymethyl chitosan nanoparticles against intracellular infections of Staphylococcus aureus

Cite this Research Publication : S. Maya, Indulekha, S., Sukhithasri, V., Smitha, K. T., Nair, S. V., Dr. Jayakumar Rangasamy, and Dr. Raja Biswas, “Efficacy of tetracycline encapsulated O-carboxymethyl chitosan nanoparticles against intracellular infections of Staphylococcus aureus”, International Journal of Biological Macromolecules, vol. 51, pp. 392-399, 2012.

Publisher : International Journal of Biological Macromolecules

Year : 2011

Anti-infective Properties of Lactobacillus Fermentum Against Staphylococcus Aureus and Pseudomonas Aeruginosa

Cite this Research Publication : P. Varma, Nisha, N., Dinesh, K. R., Kumar, A. V., and Biswas, R., “Anti-infective Properties of Lactobacillus Fermentum Against Staphylococcus Aureus and Pseudomonas Aeruginosa”, Journal of Molecular Microbiology and Biotechnology, vol. 20, pp. 137-143, 2011.

Publisher : Journal of Molecular Microbiology and Biotechnology

Year : 2010

Role of staphylococcal wall teichoic acid in targeting the major autolysin Atl

Cite this Research Publication : M. Schlag, Dr. Raja Biswas, Krismer, B., Kohler, T., Zoll, S., Yu, W., Schwarz, H., Peschel, A., and Götz, F., “Role of staphylococcal wall teichoic acid in targeting the major autolysin Atl”, Molecular Microbiology, vol. 75, pp. 864–873, 2010.

Publisher : Blackwell Publishing Ltd

Year : 2010

Lactobacillus Fermentum Isolated from Human Colonic Mucosal Biopsy Inhibits the Growth and Adhesion of Enteric and Foodborne Pathogens

Cite this Research Publication : P. Varma, Dinesh, K. R., Menon, K. K., and Dr. Raja Biswas, “Lactobacillus Fermentum Isolated from Human Colonic Mucosal Biopsy Inhibits the Growth and Adhesion of Enteric and Foodborne Pathogens”, Journal of Food Science, vol. 75, pp. M546-M551, 2010.

Publisher : Journal of Food Science

Year : 2010

Downregulation of mouse intestinal Na+-coupled glucose transporter SGLT1 by Gum Arabic (Acacia senegal)

Cite this Research Publication : O. Nasir, Artunc, F., Wang, K., Rexhepaj, R., Foeller, M., Ebrahim, A., Kempe, D. S., Dr. Raja Biswas, Bhandaru, M., Walter, M., and , “Downregulation of mouse intestinal Na+-coupled glucose transporter SGLT1 by Gum Arabic (Acacia senegal)”, Cellular Physiology and Biochemistry, vol. 25, pp. 203–210, 2010.

Publisher : Karger Publishers

Year : 2010

Author Index

Cite this Research Publication : Dr. Raja Biswas, “Author Index”, Molecular Microbiology, vol. 75, pp. 1592–1596, 2010.

Publisher : Blackwell Publishing Ltd

Year : 2009

Staphylococcus aureus survival strategy to resist Pseudomonas aeruginosa is SCV selection

Cite this Research Publication : L. Biswas, Dr. Raja Biswas, Schlag, M., Bertram, R., and Götz, F., “Staphylococcus aureus survival strategy to resist Pseudomonas aeruginosa is SCV selection”, Applied and Environmental Microbiology, 2009.

Publisher : Applied and Environmental Microbiology

Year : 2009

Small-colony variant selection as a survival strategy for Staphylococcus aureus in the presence of Pseudomonas aeruginosa

Cite this Research Publication : L. Biswas, Dr. Raja Biswas, Schlag, M., Bertram, R., and Götz, F., “Small-colony variant selection as a survival strategy for Staphylococcus aureus in the presence of Pseudomonas aeruginosa”, Applied and environmental microbiology, vol. 75, pp. 6910–6912, 2009.

Publisher : Applied and environmental microbiology

Year : 2009

Role of the twin-arginine translocation pathway in Staphylococcus

Cite this Research Publication : L. Biswas, Dr. Raja Biswas, Nerz, C., Ohlsen, K., Schlag, M., Schäfer, T., Lamkemeyer, T., Ziebandt, A. - K., Hantke, K., Rosenstein, R., and , “Role of the twin-arginine translocation pathway in Staphylococcus”, Journal of bacteriology, vol. 191, pp. 5921–5929, 2009.

Publisher : Journal of bacteriology

Year : 2009

Effect of peptidoglycans on erythrocyte survival

Cite this Research Publication : M. Föller, Dr. Raja Biswas, Mahmud, H., Akel, A., Shumilina, E., Wieder, T., Goetz, F., and Lang, F., “Effect of peptidoglycans on erythrocyte survival”, International Journal of Medical Microbiology, vol. 299, pp. 75 - 85, 2009.

Publisher : International Journal of Medical Microbiology

Year : 2009

Characterization of AtlL, a bifunctional autolysin of Staphylococcus lugdunensis with N-acetylglucosaminidase and N-acetylmuramoyl-l-alanine amidase activities

Cite this Research Publication : I. Bourgeois, Camiade, E., Dr. Raja Biswas, Courtin, P., Gibert, L., Götz, F., Chapot-Chartier, M. - P., Pons, J. - L., and Pestel-Caron, M., “Characterization of AtlL, a bifunctional autolysin of Staphylococcus lugdunensis with N-acetylglucosaminidase and N-acetylmuramoyl-l-alanine amidase activities”, FEMS Microbiology Letters, vol. 290, pp. 105–113, 2009.

Publisher : FEMS Microbiology Letters

Year : 2009

APC sensitive gastric acid secretion

Cite this Research Publication : A. Rotte, Bhandaru, M., Föller, M., Dr. Raja Biswas, Mack, A. F., Friedrich, B., Rexhepaj, R., Nasir, O., Ackermann, T. F., Boini, K. M., and , “APC sensitive gastric acid secretion”, Cellular Physiology and Biochemistry, vol. 23, pp. 133–142, 2009.

Publisher : Cellular Physiology and Biochemistry

Year : 2008

SGK1-dependent upregulation of connective tissue growth factor by angiotensin II

Cite this Research Publication : A. Hussain, Wyatt, A. W., Wang, K., Bhandaru, M., Dr. Raja Biswas, Avram, D., Föller, M., Rexhepaj, R., Friedrich, B., Ullrich, S., and , “SGK1-dependent upregulation of connective tissue growth factor by angiotensin II”, Kidney and Blood Pressure Research, vol. 31, pp. 80–86, 2008.

Publisher : Kidney and Blood Pressure Research

Year : 2008

Lipopeptides in the triggering of erythrocyte cell membrane scrambling

Cite this Research Publication : K. Wang, Mahmud, H., Föller, M., Dr. Raja Biswas, Lang, K. S., Bohn, E., Goetz, F., and Lang, F., “Lipopeptides in the triggering of erythrocyte cell membrane scrambling”, Cellular Physiology and Biochemistry, vol. 22, pp. 381–386, 2008.

Publisher : Cellular Physiology and Biochemistry

Year : 2008

Cseh, J. 47 Csiky, B. 47 Davidovitz, A. 210 Djukanović, L. 307 Donato, V. 330

Cite this Research Publication : S. G. Abdel Hamid, Abdulle, A. M., Abouchacra, S., Abraham, G., Agyemang, C., Ajdačić, M., Aleksandrowicz, E., Arena, A., Arendshorst, W. J., Avram, D., and Dr. Raja Biswas, “Cseh, J. 47 Csiky, B. 47 Davidovitz, A. 210 Djukanović, L. 307 Donato, V. 330”, Kidney Blood Press Res, vol. 31, p. 441, 2008.

Publisher : Kidney Blood Press Res

Year : 2008

Analysis of T-cell proliferation and cytokine secretion in the individuals exposed to arsenic

Cite this Research Publication : Dr. Raja Biswas, Ghosh, P., Banerjee, N., Das, J. K., Sau, T., Banerjee, A., Roy, S., Ganguly, S., M. Chatterjee, Mukherjee, A., and , “Analysis of T-cell proliferation and cytokine secretion in the individuals exposed to arsenic”, Human & experimental toxicology, vol. 27, pp. 381–386, 2008.

Publisher : Human experimental toxicology

Year : 2007

Suicidal erythrocyte death in sepsis

Cite this Research Publication : D. S. Kempe, Akel, A., Lang, P. A., Hermle, T., Dr. Raja Biswas, Muresanu, J., Friedrich, B., Dreischer, P., Wolz, C., Schumacher, U., Peschel, A., Götz, F., Döring, G., Wieder, T., Gulbins, E., and Lang, F., “Suicidal erythrocyte death in sepsis”, Journal of Molecular Medicine, vol. 85, pp. 273–281, 2007.

Publisher : Journal of Molecular Medicine

Year : 2007

A Staphylococcus aureus ypfP mutant with strongly reduced lipoteichoic acid (LTA) content: LTA governs bacterial surface properties and autolysin activity

Cite this Research Publication : I. Fedtke, Mader, D., Kohler, T., Moll, H., Nicholson, G., Dr. Raja Biswas, Henseler, K., Götz, F., Zähringer, U., and Peschel, A., “A Staphylococcus aureus ypfP mutant with strongly reduced lipoteichoic acid (LTA) content: LTA governs bacterial surface properties and autolysin activity”, Molecular Microbiology, vol. 65, pp. 1078–1091, 2007.

Publisher : Molecular Microbiology

Year : 2007

Influence of wall teichoic acid on lysozyme resistance in Staphylococcus aureus

Cite this Research Publication : A. Bera, Dr. Raja Biswas, Herbert, S., Kulauzovic, E., Weidenmaier, C., Peschel, A., and Götz, F., “Influence of wall teichoic acid on lysozyme resistance in Staphylococcus aureus”, Journal of bacteriology, vol. 189, pp. 280–283, 2007.

Publisher : Journal of bacteriology

Year : 2007

Bacteria-derived peptidoglycans constitute pathogen-associated molecular patterns triggering innate immunity in Arabidopsis

Cite this Research Publication : A. A. Gust, Dr. Raja Biswas, Lenz, H. D., Rauhut, T., Ranf, S., Kemmerling, B., Götz, F., Glawischnig, E., Lee, J., Felix, G., and , “Bacteria-derived peptidoglycans constitute pathogen-associated molecular patterns triggering innate immunity in Arabidopsis”, Journal of Biological Chemistry, vol. 282, pp. 32338–32348, 2007.

Publisher : Journal of Biological Chemistry

Year : 2006

The presence of peptidoglycan O-acetyltransferase in various staphylococcal species correlates with lysozyme resistance and pathogenicity

Cite this Research Publication : A. Bera, Dr. Raja Biswas, Herbert, S., and Götz, F., “The presence of peptidoglycan O-acetyltransferase in various staphylococcal species correlates with lysozyme resistance and pathogenicity”, Infection and immunity, vol. 74, pp. 4598–4604, 2006.

Publisher : Infection and immunity, Am Soc Microbiol

Year : 2006

Microevolution of cytochrome bd oxidase in staphylococci and its implication in resistance to respiratory toxins released by Pseudomonas

Cite this Research Publication : L. Voggu, Schlag, S., Dr. Raja Biswas, Rosenstein, R., Rausch, C., and Götz, F., “Microevolution of cytochrome bd oxidase in staphylococci and its implication in resistance to respiratory toxins released by Pseudomonas”, Journal of bacteriology, vol. 188, pp. 8079–8086, 2006.

Publisher : Am Soc Microbiol

Year : 2006

Activity of the major staphylococcal autolysin Atl

Cite this Research Publication : Dr. Raja Biswas, Voggu, L., Simon, U. Karsten, Hentschel, P., Thumm, G., and Götz, F., “Activity of the major staphylococcal autolysin Atl”, FEMS Microbiology Letters, vol. 259, pp. 260–268, 2006.

Publisher : The Oxford University Press

Conference Paper

Year : 2008

A comparative assessment of efficacy and safety of oral antidiabetic drug combinations, metformin plus pioglitazone versus metformin plus glimepiride in type-2 diabetes mellitus

Cite this Research Publication : Dr. Raja Biswas, Paul, K., Mukherjee, A. K., Bhattacherjee, I., and Mondal, S., “A comparative assessment of efficacy and safety of oral antidiabetic drug combinations, metformin plus pioglitazone versus metformin plus glimepiride in type-2 diabetes mellitus”, in INDIAN JOURNAL OF PHARMACOLOGY, 2008.

Publisher : INDIAN JOURNAL OF PHARMACOLOGY

Year : 2007

Characterisation of cell wall hydrolases in Staphylococcus sp.

Cite this Research Publication : M. Schlag, Dr. Raja Biswas, Zoll, S., and Goetz, F., “Characterisation of cell wall hydrolases in Staphylococcus sp.”, in INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2007.

Publisher : INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Year : 2006

Lipoteichoic acid governs surface properties and autolysin activity in Staphylococcus aureus

Cite this Research Publication : D. Schultz, Fedtke, I., Henseler, K., Dr. Raja Biswas, Gotz, F., Nicholson, G., and Peschel, A., “Lipoteichoic acid governs surface properties and autolysin activity in Staphylococcus aureus”, in INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2006.

Publisher : ELSEVIER GMBH, URBAN & FISCHER VERLAG OFFICE JENA

Patents

Year : 2011

THE ART, METHOD, MANNER, PROCESS AND SYSTEM OF PREPARATION OF TARGETED DELIVERY OF TETRACYCLINE LOADED O-CARBOXYMETHYL CHITOSAN NANOPARTICLES AGAINST STAPHYLOCOCCUS AUREUS

Cite this Research Publication : Raja Biswas, .Jayakumar, R., V.Nair, S., .Maya, S., and .Indulekha, S., “THE ART, METHOD, MANNER, PROCESS AND SYSTEM OF PREPARATION OF TARGETED DELIVERY OF TETRACYCLINE LOADED O-CARBOXYMETHYL CHITOSAN NANOPARTICLES AGAINST STAPHYLOCOCCUS AUREUS”, U.S. Patent 4109/CHE/20112011.

Publisher : U.S. Patent

Journal

Year : 2023

Identification of a PD1/PD-L1 inhibitor by structure-based pharmacophore modelling, virtual screening, molecular docking and biological evaluation

Cite this Research Publication : Choorakottayil Pushkaran, A., Kumaran, K., Ann Maria, T., Biswas, R., Mohan, C.G. Identification of a PD1/PD-L1 inhibitor by structure-based pharmacophore modelling, virtual screening, molecular docking and biological evaluation (2023) Molecular Informatics, 42, 2200254.

Publisher : Wiley Online Library

Year : 2023

An update on possible alternative therapeutics for future periodontal disease management

Cite this Research Publication : Das, V., Vinod, V., Biswas, L., Kumar, A., Biswas, R. An update on possible alternative therapeutics for future periodontal disease management (2023) Journal of Applied Microbiology, 134, lxac039.

Publisher : Oxford University Press

Year : 2022

Nanofibrous Facemasks with Curcumin for Improved Bacterial/Particulate Filtration and Biocidal Activity

Cite this Research Publication : Chandran R. R., Salim, A., Babu, R., Pal, S., Biswas, R., Nelson, S. B., Nair, S.V., Menon, D. Nanofibrous Facemasks with Curcumin for Improved Bacterial/Particulate Filtration and Biocidal Activity (2022) ACS Applied Polymer Materials, 4, 4839-4849.

Publisher : ACS Publications

Year : 2022

Enhanced inhibition of Pseudomonas aeruginosa virulence factor production and biofilm development by sublethal concentrations of eugenol and phenyllactic acid

Cite this Research Publication : Shariff, M., Chatterjee, M., Morris, S.D., Vasudevan A.K., Mohan C.G., Paul-Prasanth, B., Biswas, R. Enhanced inhibition of Pseudomonas aeruginosa virulence factor production and biofilm development by sublethal concentrations of eugenol and phenyllactic acid (2022) Letters in Applied Microbiology, 75, 1336-1345.

Publisher : Blackwell Science Ltd Oxford, UK

Year : 2022

Inhibitory potential of chromene derivatives on structural and non-structural proteins of dengue virus

Cite this Research Publication : Dharmapalan, B.T., Biswas, R., Sankaran, S., Venkidasamy, B., Thiruvengadam, M., George, G., Rebezov, M., Zengin, G., Gallo M., Montesano, D., Naviglio, D., Shariati, M.A. Inhibitory Potential of Chromene Derivatives on Structural and Non-Structural Proteins of Dengue Virus (2022) Viruses, 14, 2656.

Publisher : MDPI

Thesis

Year : 2006

Characterization of Staphylococcus Aureus Peptidogylcan [peptidoglycan] Hydrolases and Isolation of Defined Peptidoglycan Structures

Cite this Research Publication : Dr. Raja Biswas, “Characterization of Staphylococcus Aureus Peptidogylcan [peptidoglycan] Hydrolases and Isolation of Defined Peptidoglycan Structures”, 2006.

Year : 2006

Characterization of Staphylococcus aureus peptidoglycan hydrolases and isolation of defined peptidoglycan structures

Cite this Research Publication : Dr. Raja Biswas and , “Characterization of Staphylococcus aureus peptidoglycan hydrolases and isolation of defined peptidoglycan structures”, Universität Tübingen, 2006.

Publisher : Universität Tübingen

Research

A significant part of human evolution was dedicated to developing ways to thwart microbial intrusion. Discovery of antibiotics and advent of vaccination contributed in reducing the number of death due to infectious diseases. However, changes in environment, population explosion, urbanization and misuse of the antibiotics along with the diminished effectiveness of approaches to disease control, has led to emergence and reemergence of many infectious diseases. It is estimated that infectious diseases are the leading cause of death after cancer and heart diseases.

Many of the microbes are constant human companion which can turn into pathogens given a chance. Bacterial colonization does not necessarily prevent infection but does elicit specific antibody response. These contradicting observations makes a thorough understanding of human and pathogen interaction imperative for the discovery of new mechanisms to combat microbial infections.

The infectious lab works on developing methods to prevent and minimize microbial infections by interrupting the bacterial pathogenesis. We aim to translate the understanding of human –pathogen interaction to design novel preventive and therapeutic strategies against microbes. As a successful step towards translation of our findings into clinical use, Drosophila melanogaster model for infectious has been developed in our lab.

 

Main Research Focus
  • Understanding the pathogenesis and prevention of sepsis and septic arthritis caused by Staphylococcus aureus.
  • Understanding the structural- function relationship between host protein and bacterial ligand, in collaboration with Dr. Gopi Mohan.
  • Development of hydrogels and bandages for the treatment of infections in collaboration with Dr. R. Jayakumar.
  • Investigating the potential of nano-drug delivery for treating infectious diseases.
  • Studying the potential of probiotic for disease prevention.
  • Establishing the repository for long-term storage of samples to study the genetic changes leading to cancer in HPV patients.

 

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