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Dr. Pandurangan Nanjan

Assistant Professor (Sl. Gr.), Department of Chemistry, School of Physical Sciences, Coimbatore.

Qualification: BSc, MSc, Ph.D
n_pandurangan@cb.amrita.edu
Scopus Author ID
Research Interest: Organic/Natural Product/Polymer Chemistry

Bio

Dr. N. Pandurangan has a doctorate in Synthetic and Natural Product Chemistry from Amrita Vishwa Vidyapeetham, India. He specializes in various fields of organic/natural product and medicinal chemistry.

He was an Institute Post-doctoral Fellow at the Department of Chemistry, Indian Institute of Technology Palakkad, Kerala, India. During his post-doctoral stay (2018-2021), he was instrumental in setting up laboratory for the development of sequence-defined polymers and their applications in bio-medical and material sciences.

Dr. N. Pandurangan bridges academic experience with expertise in industry. He had industrial experience of three years (2006-2009) during which he worked on production of speciality chemicals for rubber products development.

He was also involved in the DBT project (2009-2011) for phytochemical characterization of Seabuckthorn plant under the guidance of Prof.Asoke Banerji at School of Biotechnology, Amrita Vishwa Vidyapeetham, which led him to getting awarded the CSIR-SRF from Council for Scientific and Industrial Research in 2014. He currently serves as Assistant Professor (Sl.Gr) in Physical Sciences,  Amrita School of Physical sciences, Coimbatore.

Publications

Journal Article

Year : 2023

Pyrrole: A Decisive Scaffold for the Development of Therapeutic Agents and Structure-Activity Relationship

Cite this Research Publication : Bharathi Hassan Ganesh, Anirudh G. Raj, Dr. Baladhandapani Aruchamy, Dr. Pandurangan Nanjan*, Dr. Carmelo Drago, Dr. Prasanna Ramani*, Pyrrole: A Decisive Scaffold for the Development of Therapeutic Agents and Structure-Activity Relationship, https://doi.org/10.1002/cmdc.202300447 (First published: 05 November 2023 )

Year : 2022

CuO/CaO as a solid reducing reagent for nitroarenes: combined effect of oxygen vacancies and surface basicity

Cite this Research Publication : K Rajendran, S Akash, M Roshni, Nanjan Pandurangan, D Jagadeesan. CuO/CaO as a solid reducing reagent for nitroarenes: combined effect of oxygen vacancies and surface basicity. Proceedings of the Indian National Science Academy, 2022, 1-10. (Impact factor: NA).

Publisher : Springer Link

Year : 2022

Design, synthesis and bioactive properties of a class of macrocycles with tunable functional groups and ring size

Cite this Research Publication : Liya Thurakkal, Pandurangan Nanjan, Mintu Porel. Design, synthesis and bioactive properties of a class of macrocycles with tunable functional groups and ring size. Scientific reports, 12, 1-9. (Impact factor: 4.996).

Publisher : Scientific Reports

Year : 2022

CuO/CaO mediated synthesis of amino-1, 8-naphthalimides from the nitro analogues

Cite this Research Publication : Karuppusamy Rajendran, Ananthu Shanmughan, Pandurangan Nanjan, Deepak Krishnan Balaji, Sankarasekaran Shanmugaraju, Dinesh Jagadeesan. CuO/CaO mediated synthesis of amino-1, 8-naphthalimides from the nitro analogues. Results in Chemistry, 2022, 4, 100430. (Impact factor: NA).

Publisher : science direct

Year : 2022

Chalcone: A promising bioactive scaffold in medicinal chemistry

Cite this Research Publication : Gayathri Rajendran, Deepu Bhanu, Baladhandapani Aruchamy, Prasanna Ramani, Nanjan Pandurangan, Kondapa Naidu Bobba, Eun Jung Oh, Ho Yun Chung, Prakash Gangadaran, Byeong-Cheol Ahn, "Chalcone: A promising bioactive scaffold in medicinal chemistry", Pharmaceuticals Volume 15 Issue 10 Pages 1250, 2022

Publisher : MDPI

Year : 2021

CuO as a reactive and reusable reagent for the hydrogenation of nitroarenes

Cite this Research Publication : K Rajendran, Nanjan Pandurangan, CP Vinod, Tuhin S Khan, Shelaka Gupta, M Ali Haider, D Jagadeesan. CuO as a reactive and reusable reagent for the hydrogenation of nitroarenes. Applied Catalysis B: Environmental. 2021, 120417. (Impact factor: 24.319).

Publisher : Elsevier

Year : 2021

Recent advances in luminescent metal–organic frameworks (LMOFs) based fluorescent sensors for antibiotics

Cite this Research Publication : Pandi Raja Lakshmia, Pandurangan Nanjana, Sukanya Kannan, Sankarasekaran Shanmugaraju. Recent advances in luminescent metal–organic frameworks (LMOFs) based fluorescent sensors for antibiotics. Coordination Chemistry Reviews, 2021, 435, 213793. (Impact factor: 24.833); a – equal first author.

Publisher : Elsevier

Year : 2021

Sequence-defined oligomer as a modular platform for selective sub-picomolar detection and removal of Hg 2+

Cite this Research Publication : Anna Jose, Pandurangan Nanjan, Mintu Porel. Sequence-defined oligomer as a modular platform for selective sub-picomolar detection and removal of Hg 2+. Polymer Chemistry, 2021, 12, 5201-5208. (Impact factor: 5.364).

Publisher : Polymer Chemistry

Year : 2021

Proteasomal dysfunction and ER stress triggers 2’‐hydroxy‐retrochalcone induced paraptosis in cancer cells

Cite this Research Publication : Divya Nedungadi, Anupama Binoy, Nanjan Pandurangan, Bipin G Nair, Nandita Mishra. Proteasomal dysfunction and ER stress triggers 2′-hydroxy-retrochalcone-induced paraptosis in cancer cells. Cell Biology International, 2021, 45, 164-175. (Impact factor: 4.473).

Publisher : Wiley Online Library

Year : 2021

Nuclear factor-κB plays an important role in Tamarixetin-mediated inhibition of matrix metalloproteinase-9 expression.

Cite this Research Publication : Shaji Sanu K., G. Drishya, Damu Sunilkumar, Nanjan Pandurangan, Dr. Geetha Kumar, and Dr. Bipin G. Nair, “Nuclear factor-κB plays an important role in Tamarixetin-mediated inhibition of matrix metalloproteinase-9 expression.”, European Journal of Pharmacology, vol. 893, p. 173808, 2021.

Publisher : European Journal of Pharmacology

Year : 2020

Sequence-Defined Dithiocarbamate Oligomers via a Scalable, Support-free, Iterative Strategy

Cite this Research Publication : Pandurangan Nanjan, Anna Jose, Liya Thurakkal, Mintu Porel. Sequence-Defined Dithiocarbamate Oligomers via a Scalable, Support-free, Iterative Strategy. Macromolecules, 2020, 53, 24, 11019–11026. (Impact factor: 6.057).

Publisher : ACS

Year : 2020

Potent Chitin Synthase Inhibitors from Plants

Cite this Research Publication : A. Vijayakumar, Ajith Madhavan, Chinchu Bose, Nanjan Pandurangan, Sindhu Shetty K., Archana Palillamvedu, Megha Prasad, Dr. Sanjay Pal, and Dr. Bipin G. Nair, “Potent Chitin Synthase Inhibitors from Plants”, Current Bioactive Compounds, vol. 14, 2018.

Publisher : Current Bioactive Compounds

Year : 2019

Sequence-defined non-natural polymers; Synthesis and applications

Cite this Research Publication : Nanjan Pandurangan and Mintu Porel. Sequence-defined non-natural polymers; Synthesis and applications. Polymer Chemistry, 2019, 10, 5406-5424. (Impact factor: 5.342).

Publisher : Polymer chemistry

Year : 2018

Synthesis, Bioactivities and in-silico Docking Studies of Azaleatin-a Quercetin Partial Methyl Ether; SAR Study

Cite this Research Publication : Pandurangan Nanjan, Chinchu Bose, M. Sreejith, Veni C K, Anjana M Amrita, and Anjana R P., “Synthesis, bioactivities and in-silico docking studies of azaleatin-a quercetin partial methyl ether; SAR study.”, vol. 14, 2018

Publisher : BENTHEM SCIENCE

Year : 2018

(I-3,II-3)-Biacacetin-mediated Cell Death involves Mitochondria

Cite this Research Publication : Jyotsna Nambiar, Gayathri Vijayakumar, G. Drishya, Sanu K Shaji, Nanjan Pandurangan, Geetha B. Kumar, and Dr. Bipin G. Nair, “(I-3,II-3)-Biacacetin-mediated cell death involves mitochondria.”, Molecular and cellular biochemistry, 2018

Publisher : Molecular and cellular biochemistry

Year : 2018

6-Shogaol induces caspase-independent paraptosis in cancer cells via proteasomal inhibition

Cite this Research Publication : Nedungadi, D., Binoy, A., Pandurangan, N., Pal, S., Nair, B.G., and Mishra, N. (2018). 6-Shogaol induces caspase-independent paraptosis in cancer cells via proteasomal inhibition. Exp. Cell Res. 364 (2), 243-251.

Publisher : Exp. Cell Res

Year : 2017

A rapid, solvent-free deprotection of methoxymethyl (MOM) ethers by pTSA; an eco-friendly approach

Cite this Research Publication : Nanjan Pandurangan*, A rapid, solvent-free deprotection of methoxymethyl (MOM) ethers by pTSA; an eco-friendly approach. Letters in Organic Chemistry, 2017, 14, 231-235. (Impact factor: 0.723)

Publisher : Ingenta Connect

Year : 2017

Coconut Shell Derived Bioactive Compound Oxyresveratrol Mediates Regulation Of Matrix Metalloproteinase 9

Cite this Research Publication : Damu Sunilkumar, Chinchu Bose, Sanu K Shaji, Nanjan Pandurangan, Geetha B Kumar, Asoke Banerji, and Dr. Bipin G. Nair, “Coconut Shell Derived Bioactive Compound Oxyresveratrol Mediates Regulation Of Matrix Metalloproteinase 9”, International Journal of Pharma and Bio Sciences, vol. 8, no. 1, pp. 202 – 210, 2017.

Publisher : International Journal of Pharma and Bio Sciences

Year : 2016

Nitric Oxide and ERK Mediates Regulation of Cellular Processes by Ecdysterone

Cite this Research Publication : A. Omanakuttan, Chinchu Bose, N., P., G. B. Kumar, A. Banerji, and Dr. Bipin G. Nair, “Nitric Oxide and ERK mediates regulation of cellular processes by Ecdysterone”, Experimental Cell Research, vol. 346, no. 2, pp. 167-175, 2016.

Publisher : Experimental Cell Research .

Year : 2016

Discovery of Arjunolic Acid as a Novel Non-zinc Binding Carbonic Anhydrase II Inhibitor

Cite this Research Publication : S. Kalyanavenkataraman, Pandurangan Nanjan, Dr. Asoke Banerji, Dr. Bipin G. Nair, and Geetha B Kumar, “Discovery of arjunolic acid as a novel non-zinc binding carbonic anhydrase II inhibitor”, Bioorganic chemistry, vol. 66, pp. 72–79, 2016

Publisher : Bioorganic chemistry

Year : 2016

Clove Bud Oil Reduces Kynurenine and Inhibits pqs A Gene Expression in P. Aeruginosa

Cite this Research Publication : Jayalekshmi H., A. Omanakuttan, N. Pandurangan, V. S. Vargis, M. Maneesh, Dr. Bipin G. Nair, and Geetha B. Kumar, “Clove Bud Oil Reduces Kynurenine and Inhibits pqs A Gene Expression in P. Aeruginosa”, Applied microbiology and biotechnology, vol. 100, no. 8, pp. 3681-3692, 2016

Publisher : Applied microbiology and biotechnology

Year : 2015

Synthesis and Discovery of (I-3,II-3)-Biacacetin as a Novel Non-zinc Binding Inhibitor of MMP-2 and MMP-9

Cite this Research Publication : Pandurangan Nanjan, Dr. Jyotsna Nambiar, Dr. Bipin G. Nair, and Dr. Asoke Banerji, “Synthesis and Discovery of (I-3,II-3)-Biacacetin as a Novel Non-zinc Binding Inhibitor of MMP-2 and MMP-9”, Bioorganic & Medicinal Chemistry, vol. 23, pp. 3781 - 3787, 2015

Publisher : Bioorganic Medicinal Chemistry

Year : 2014

A new synthesis for acacetin, chrysoeriol, diosmetin, tricin and other hydroxylated flavones by modified baker-venkataraman transformation

Cite this Research Publication : Pandurangan Nanjan and Dr. Asoke Banerji, “A new synthesis for acacetin, chrysoeriol, diosmetin, tricin and other hydroxylated flavones by modified baker-venkataraman transformation”, Letters in Organic Chemistry, vol. 11, pp. 225–229, 2014.

Publisher : Letters in Organic Chemistry

Year : 2014

Discovery of lesser known flavones as inhibitors of NF-κB signaling in MDA-MB-231 breast cancer cells-A SAR study

Cite this Research Publication : Ka Amrutha, Pandurangan Nanjan, Shaji, S. Ka, Sunilkumar, Da, Subhalakshmi, Ka, Rajakrishna, Lb, and Dr. Asoke Banerji, “Discovery of lesser known flavones as inhibitors of NF-κB signaling in MDA-MB-231 breast cancer cells-A SAR study”, Bioorganic and Medicinal Chemistry Letters, vol. 24, no. 19, pp. 4735-4742, 2014.

Publisher : Bioorganic and Medicinal Chemistry Letters

Year : 2012

Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9

Cite this Research Publication : A. Omanakuttan, Dr. Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Pandurangan Nanjan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Dr. Asoke Banerji, J. Jefferson P. Perry, and Dr. Bipin G. Nair, “Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9”, Molecular Pharmacology, vol. 82, no. 4, pp. 614-622, 2012

Publisher : Molecular Pharmacology

Year : 2011

Synthesis and anti-oxygenic activities of seabuckthorn flavone-3-ols and analogs

Cite this Research Publication : Nanjan Pandurangan, Chinchu Bose, Asoke Banerji. Synthesis and anti-oxygenic activities of seabuckthorn flavone-3-ols and analogs. Bioorganic & Medicinal Chemistry Letters, 2011, 21, 5328-5330. (Impact factor: 2.94)

Publisher : Science direct

Conference Proceedings

Year : 2016

First Regio-specific Synthesis of Pachypodol from Onion peel waste; Discovery of non-zinc binding inhibitor of MMP-2

Cite this Research Publication : Nanjan Pandurangan, Jyotsna Nambiar, Bipin G. Nair, Asoke Banerji. Best oral presentation award for the title entitled “First Regio-specific Synthesis of Pachypodol from Onion peel waste; Discovery of non-zinc binding inhibitor of MMP-2” in National Conference on Recent Advances in “Drug Design using Computational Chemistry Tools-Case Studies” 2016 at JSS College, Ooty, Tamilnadu, India.

Year : 2013

Regio-specific Synthesis and Comparative radical Scavenging Activities of Flavones and Flavonols

Cite this Research Publication : Nanjan Pandurangan and Asoke Banerji. Regio-specific Synthesis and Comparative radical Scavenging Activities of Flavones and Flavonols. Conference Proceedings-Biotechnology for innovative applications -Amrita Bioquest-2013.

Year : 2012

Bioprospection of Kerala flora for Phytoecdysoids: value addition to biodiversity

Cite this Research Publication : Sreejit C. M. Chinchu Bose, Nanjan Pandurangan, Thomas Mathew P. and A. Banerji. Bioprospection of Kerala flora for Phytoecdysoids: value addition to biodiversity. National Symposium on Innovative and modern technologies for agricultural productivity, food security and environmental management by the society for applied biotechnology, 2012.

Year : 2012

Synthesis and Antioxygenic Activities of Seabuckthorn Flavones-3-ols and Analogs

Cite this Research Publication : Nanjan Pandurangan, Chinchu Bose and A. Banerji. Synthesis and Antioxygenic Activities of Seabuckthorn Flavones-3-ols and Analogs. UGC Sponsored National seminar on Modern trends in organic chemistry. 2012.

Year : 2011

Isolation, Characterization and Synthesis of Bioactive Flavonols from Seabuckthorn

Cite this Research Publication : Chinchu Bose, Nanjan Pandurangan and A. Banerji. Isolation, Characterization and Synthesis of Bioactive Flavonols from Seabuckthorn. Medicinal chemistry in India; Medicinal chemistry Congress, NIPER/IICT, 2011.

Year : 2010

Finger-printing of Secondary Metabolites from Medicinal plants.

Cite this Research Publication : Nanjan Pandurangan, Chinchu Bose, A. Banerji. Finger-printing of Secondary Metabolites from Medicinal plants. U.G.C. sponsored National seminar on Medicinal Plants and Pharmacopia. 2010.

Book Chapter

Year : 2022

Bio-sensing properties of supramolecular coordination complexes-Chapter 9

Cite this Research Publication : Dipanjana Sarkara, Pandurangan Nanjan and Sankarasekaran Shanmugaraju. Bio-sensing properties of supramolecular coordination complexes, Chapter 9, Accepted for publication (2022).

Publisher : Science Direct

Year : 2014

Isolation, Characterization and Chemical Fingerprinting of Bioactives from Indian Seabuckthorn (Hippophae L.) Species

Cite this Research Publication : Pandurangan Nanjan, Chinchu Bose, Singh, V., and Dr. Asoke Banerji, “Isolation, Characterization and Chemical Fingerprinting of Bioactives from Indian Seabuckthorn (Hippophae L.) Species”, in Seabuckthorn (Hippophae L.) : A Multipurpose Wonder Plant : Vol. IV: Emerging Trends in Research and Technologies, vol. 4, 2014, p. 262.

Publisher : Seabuckthorn (Hippophae L.) : A Multipurpose Wonder Plant : Vol. IV: Emerging Trends in Research and Technologies

Patents

Year : 2022

Class of sequence-defined polymers and preparation methods

Cite this Research Publication : Nanjan Pandurangan and Mintu Porel, Class of sequence-defined polymers and preparation methods thereof, US Patent Published (No. 11427682; dated: 30 Aug 2022).

Qualification
  • July 2011 – January 2017, PhD in Organic/Natural Product Chemistry, School of Biotechnology, Amrita University, Kerala, India. 
  • 2004-2006, MSc in Chemistry, Periyar University, Salem, India. 
  • 2000-2003, BSc in Chemistry, Govt. Arts College, Ooty, Tamilnadu, India. 
Experiences
  • July 2021-till date: Assistant Professor (Sl. Gr), Amrita Vishwa Vidyapeetham, Mysuru Campus, Mysuru, Karnataka, India.
  • July 2018-June 2021, Institute Post-Doctoral Fellow in the department of chemistry, Indian Institute of Palakkad (IITP), Kerala, India.

Project title: Developing new synthetic Strategy for sequence-defined polymers and study of their applications in bio-medical and material sciences.

  • July 2011-February 2018, PhD Scholar under the guidance of Distinguished Prof. Asoke Banerji, School of Biotechnology, Amrita University, Kerala, India.

Thesis title: Bio-inspired diversity-diversity oriented synthesis of partially-methylated flavonoids, bioactivities and their in-silico modelling studies.

  • August 2009-May 2011, Senior Research Fellow under the guidance of Distinguished Prof. Asoke Banerji, School of Biotechnology, Amrita University, Kerala, India.

Project title; Isolation and characterization of bioactive compounds from Indian Seabuckthorn Plant under DBT sponsored Project.

  • July 2006-August 2009, three years in Industry as Research Associate dealing with synthesis of specialty chemicals such as benzothiazoles, sulphenamides, quinolone derivatives, thiuram and dithiocarbamates (Synthetic organic chemistry).
  • 2013 Training on HPLC-MS under Prof. Walter Schrenck (Agilent Technologies) from Amrita- Agilent Analytical Research Centre, School of Biotechnology, Amrita University, Kerala, India.

 

Reviewer/Editorial Board Member

Reviewer

  1. Journal of molecular structure
  2. Letters in organic chemistry
  3. Medicinal chemistry research
  4. Current Bioactive compounds
  5. Results in Chemistry
Awards

Awards/Fellowship

  • Awarded Senior Research Fellowship on 2014 by Council of Science and Industrial Research (CSIR), Delhi, India. 
  • Best oral presentation award for the title entitled “First regio-specific synthesis of pachypodol from onion peel waste; Discovery of non-zinc binding inhibitor of MMP-2” in National Conference on Recent Advances in “Drug Design using Computational Chemistry Tools-Case Studies” 4-5th November-2016 at JSS College, Ooty, Tamilnadu, India. 
Papers Presented in Seminars/Conferences
  • Best oral presentation award for the title entitled “First regio-specific synthesis of pachypodol from onion peel waste; Discovery of non-zinc binding inhibitor of MMP-2” in National Conference on Recent Advances in “Drug Design using Computational Chemistry Tools-Case Studies” 4-5th November-2016 at JSS College, Ooty, Tamilnadu, India.
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