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Dr. Navin Mathew

Professor, Department of Cardiology, School of Medicine, Kochi

Qualification: DM, MBBS, MD
navinmathew@aims.amrita.edu

Bio Publications Area of Expertise Qualification Work Experience Awards and Recognition Projects Presentations 
Bio

Dr. Navin Mathew is a highly experienced cardiologist with over 21 years of dedicated clinical practice in cardiovascular medicine. His extensive expertise spans a wide range of interventional cardiology procedures, with significant experience in performing complex coronary and peripheral interventions. Dr. Navin Mathew has been at the forefront of his field, serving as a primary operator for thousands of procedures, including coronary angiograms, coronary angioplasties, and advanced echocardiography assessments. He has successfully performed over 8,000 coronary angiograms, 2,000 coronary angioplasties, and numerous other specialized procedures, underscoring his expertise and dedication to advancing cardiovascular care.

Publications

Journal Article

Year : 2021

Boy with a Broken Heart : A Case of Post-Traumatic Left Ventricular Dissection

Cite this Research Publication : Paul A, Mathew N. "Boy with a Broken Heart : A Case of Post-Traumatic Left Ventricular Dissection," Circulation: Cardiovascular Imaging. 2021;14:e011671. doi: 10.1161/CIRCIMAGING.120.011671

Publisher : Circulation: Cardiovascular Imaging

Year : 2020

Changes in Left Ventricular Mass and Cardiovascular Risk Factors after Kidney Transplantation

Cite this Research Publication : Sreedharan S, Mathew A, Paul Z, Mathew N, Sundaram KR, Kurian G, Nair R., "Changes in Left Ventricular Mass and Cardiovascular Risk Factors after Kidney Transplantation," Saudi Journal of Kidney Diseases and Transplantation, 2020 Sep-Oct;31(5):1006-1013. doi: 10.4103/1319-2442.301165. PMID: 33229763.

Publisher : Saudi Journal of Kidney Diseases and Transplantation

Year : 2020

The prognostic value of dispersion of repolarization in stress cardiomyopathy

Cite this Research Publication : Subramanian M, Ahamed H, Prabhu M, Mathew N, Harakrishnan MS, Pai PG, Natarajan K. "The prognostic value of dispersion of repolarization in stress cardiomyopathy," Journal of Electrocardiology, 2020;62:79-85. doi:10.1016/j.jelectrocard.2020.03.006

Publisher : Journal of Electrocardiology

Year : 2020

Right ventricular dysfunction in stress cardiomyopathy: The prognostic value of fractional area change

Cite this Research Publication : Subramanian M, Ahamed H, Reddy C, Mathew N, Chandrasekhar R., "Right ventricular dysfunction in stress cardiomyopathy: The prognostic value of fractional area change," Echocardiography. 2020;10.1111/echo.14832. doi:10.1111/echo.14832

Publisher : Echocardiography

Year : 2020

Phenotypic expression and clinical outcomes in a South Asian PRKAG2 cardiomyopathy cohort

Cite this Research Publication : Hisham Ahamed , Aniketh Vijay Balegadde , Shilpa Menon , Ramesh Menon , Aishwarya Ramachandran , Navin Mathew , K. U. Natarajan , Indu Ramachandran Nair , Rajesh Kannan , Meghna Shankar , Oommen K. Mathew , Thong T. Nguyen , Ravi Gupta , Eric W. Stawiski , V. L. Ramprasad , Somasekar Seshagiri & Sameer Phalke, Phenotypic expression and clinical outcomes in a South Asian PRKAG2 cardiomyopathy cohort, Nature Scientific Reports 2020.

Year : 2019

Arrhythomgenic right ventricular cardiomyopathy and sick sinus syndrome : a potential overlap syndrome

Cite this Research Publication : Subramanian M, Peravali S, Ahamed H, Mathew N., "Arrhythomgenic right ventricular cardiomyopathy and sick sinus syndrome : a potential overlap syndrome," European Heart Journal Cardiovascular Imaging. 2019. 10.1093/ehjci/jez110.011.

Publisher : European Heart Journal Cardiovascular Imaging

Year : 2019

Young Stroke: An Unusual Presentation of Arrhythmogenic Right Ventricular Dysplasia

Cite this Research Publication : Parikh JM, Ganeshwala G, Mathew N, Venkitachalam A, Natarajan K. U., "Young Stroke: An Unusual Presentation of Arrhythmogenic Right Ventricular Dysplasia," Neurology India, 2019; 67:1528-31. DOI: 10.4103/0028-3886.273639

Publisher : Neurology India

Year : 2019

Comparison of clinical and electrophysiological characteristics of ictal asystole and cardiac asystole encountered during video-electroencephalographic monitoring

Cite this Research Publication : Sankaranarayanan, Muthukani; Makhija, Prashant; Gopinath, Siby; Mathew, Navin; Radhakrishnan, Kurupath, "Comparison of clinical and electrophysiological characteristics of ictal asystole and cardiac asystole encountered during video-electroencephalographic monitoring," Epileptic Disord, 2019 Aug 1;21(4):337-346. doi: 10.1684/epd.2019.1085.

Year : 2019

Arrhythmogenic right ventricular cardiomyopathy and sick sinus syndrome : a potential overlap syndrome

Cite this Research Publication : M. Subramanian, Peravali, S., Dr. Hisham Ahamed, and Navin Mathew, “Arrhythmogenic right ventricular cardiomyopathy and sick sinus syndrome : a potential overlap syndrome”, European Heart Journal - Cardiovascular Imaging , vol. 20, Suppliment 2, p. ii53, 2019.


Publisher : European Heart Journal - Cardiovascular Imaging

Year : 2018

Primary transcatheter closure of post-myocardial infarction ventricular septal rupture using amplatzer atrial septal occlusion device: A study from tertiary care in South India

Cite this Research Publication : Aggarwal M, Natarajan K, Vijayakumar M, Chandrasekhar R, Mathew N, Vijan V, Vupputuri A, Chintamani S, Rajendran BK, Thachathodiyl R. "Primary transcatheter closure of post-myocardial infarction ven- tricular septal rupture using amplatzer atrial septal occlusion device: A study from tertiary care in South India," Indian Heart Journal, 2018 Jul-Aug;70(4):519-527. doi: 10.1016/j.ihj.2018.01.036.

Publisher : Indian Heart Journal

Year : 2017

Familial restrictive cardiomyopathy: A novel troponin mutation

Cite this Research Publication : M. Subramanian, Dr. Hisham Ahamed, and Mathew, N., “Familial restrictive cardiomyopathy: A novel troponin mutation”, Indian Heart Journal, vol. 69, Suppliment 2, pp. S87 - S88, 2017.

Publisher : Indian Heart Journal

Year : 2016

Surviving All Odds: A Unique Case of Multiple Congenital Unruptured Sinus of Valsalva Aneurysms Involving Both Left and Right Coronary Sinuses with Biventricular Dysfunction and Heart Block.

Cite this Research Publication : Vijay B A, Vijan V, Mathew N. "Surviving All Odds: A Unique Case of Multiple Congenital Unruptured Sinus of Valsalva Aneurysms Involving Both Left and Right Coronary Sinuses with Biventricular Dysfunction and Heart Block," Case Rep Cardiol. 2016;2016:4654031. doi: 10.1155/2016/4654031.

Publisher : Case Reports in Cardiology

Year : 2016

A rare case of fatal endocarditis and sepsis caused by Pseudomonas aeruginosa in a patient with chronic renal failure

Cite this Research Publication : M. Aggarwal, Vijan, V., Vupputuri, A., Nandakumar, S., and Navin Mathew, “A rare case of fatal endocarditis and sepsis caused by Pseudomonas aeruginosa in a patient with chronic renal failure”, Journal of Clinical and Diagnostic Research, vol. 10, pp. OD12-OD13, 2016.

Publisher : Journal of Clinical and Diagnostic Research

Year : 2016

A randomized study of coconut oil versus sunflower oil on cardiovascular risk factors in patients with stable coronary heart disease

Cite this Research Publication : M. Vijayakumar, Vasudevan, D. M., Sundaram, K. R., Krishnan, S., Vaidyanathan, K., Nandakumar, S., Chandrasekhar, iv, R., and Mathew, N., “A randomized study of coconut oil versus sunflower oil on cardiovascular risk factors in patients with stable coronary heart disease”, Indian Heart Journal, 2016.

Publisher : Indian Heart Journal

Year : 2013

Cardiac anaphylaxis: a case of acute ST-segment elevation myocardial infarction after IM epinephrine for anaphylactic shock.

Cite this Research Publication : Tummala K, Maniyal VK, Chandrashekaran R, Mathew N, Ganeshwala G., "Cardiac anaphylaxis: a case of acute ST-segment elevation myocardial infarction after IM epinephrine for anaphylactic shock," The American Journal of Emergency Medicine, 2013 Jul;31(7):1157.e1-3. doi: 10.1016/j.ajem.2013.03.025. 

Publisher : The American Journal of Emergency Medicine

Year : 2011

Timing of adverse events during fibrinolytic therapy with streptokinase for left-sided prosthetic valve thrombosis

Cite this Research Publication : Karthikeyan G, Mathew N, Math RS, Devasenapathy N, Kothari SS, Bahl VK., "Timing of adverse events during fibrinolytic therapy with streptokinase for left-sided prosthetic valve thrombosis," Journal of Thrombosis and Thrombolysis, 2011 Aug;32(2):146-9. doi: 10.1007/s11239-011-0579-4.

Publisher : Journal of Thrombosis and Thrombolysis

Year : 2009

Accelerated Infusion of Streptokinase for the Treatment of Left-Sided Prosthetic Valve Thrombosis: A Randomized Controlled Trial

Cite this Research Publication : Ganesan Karthikeyan, Ravi S. Math, Navin Mathew, Bhima Shankar, Mani Kalaivani, Sandeep Singh, Vinay K. Bahl, Jack Hirsh, and John W. Eikelboom, "Accelerated Infusion of Streptokinase for the Treatment of Left-Sided Prosthetic Valve Thrombosis: A Randomized Con- trolled Trial," Circulation, Sep 2009; 120: 1108 - 1114. doi: 10.1161/CIRCULATIONAHA.109.876706.

Publisher : Circulation

Area of Expertise
  • Coronary Angiography and Angioplasty
  • Peripheral Angioplasty (Limb Vessels, Renal Arteries)
  • Balloon Valvotomies
  • Permanent Pacemaker Implantation
  • Atrial Septal Defect (ASD) Device Closure
  • Automatic Implantable Cardioverter Defibrillator (AICD) Implantation
  • Carotid Angioplasty
  • Transcatheter Aortic Valve Implantation (TAVI)
  • Endovascular Aortic Aneurysm Repair
  • Cardiac Resynchronization Therapy (CRT) Implantation
  • Ventricular Septal Rupture (VSR) Device Closure
  • Advanced Echocardiography (Tissue Doppler, Dysynchrony Assessments)
  • Transesophageal Echocardiography
  • Dobutamine Stress Echocardiography
  • IVUS/OCT Guided Angioplasties and Interpretation
Qualification
  • MBBS (Bachelor of Medicine and Bachelor of Surgery)
    Government Medical College Trichur Februvary 1996
  • MD, Internal Medicine (Postgraduate Degree in Internal Medicine)
    Stanley Medical College Chennai (March 2001)
  • DNB General Medicine
    June 2001
  • DM Cardiology
    (AIIMS) All India Institute of Medical Sciences New Delhi, (December 2005)
Work Experience
  • Pool Officer Fellow
    All India Institute of Medical sciences New Delhi
  • Assitant professor Dept of Cardiology 
    Amrita School of Medicine, Kochi
  • Associate professor Dept of Cardiology 
    Amrita School of Medicine, Kochi
  • Additional professor in Cardiology– August 2010 – Feb 2014
    Amrita School of Medicine, Kochi

Current Appoinment

  • Professor in Cardiology – Feb 2014 – Present
    Amrita School of Medicine, Kochi
Awards and Recognition
  • Jagesh Lal Kapila medal for being the best post graduate in cardiology AIIMS 2005
Projects

1. RELY-ABLE Protocol#1160.71 Title:- Long Term Multi-center Extension of Dabigatran Treatment in Patients with Atrial Fibrillation Who Completed the RE-LY trial and cluster Randomised Trial to Asses the Effect of a Knowledge Translation Interven- tion on Patient Outcomes

Principal Investigator : Dr.K.K.Haridas, Co- Investigator Dr Navin Mathew

2. ASTRONAUT Study Protocol CSPP100A2366-A multicenter,randomized,double blind, parallel group, placebo controlled study to evaluate the 6 months efficacy and safety of Aliskiren therapy on top of standard therapy, on morbidity and mortality when initiated early after hospitalization for acute decompensated heart failure.

Principal Investigator : Dr.M.VijayaKumar, Co- Investigator Dr Navin Mathew

3.PEACH HF Study-Safety and efficacy of TRC4186 in the treatment of stable Heart Failure associated with HbA1c > 6.5% or type 2 Diabetes receiving oral Hy- poglcemic Therapy (with or without additional Insulin)as an –odd to conventional treat- ment for Heart Failure.

Principal Investigator : Dr.K.K.Haridas, Co- Investigator Dr Navin Mathew

Presentations 

Abstract Presentations

Subramanian M, Mathew N, Ahamed H, Arabadi A, Narasimhan C, “RAVE Score : Derivation and Validation Model for Prognostication of Patients with Light Chain Cardiac Amyloidosis,” Society of Heart Failure and Transplantation (Feburary 2019) –  Oral Presentation 

Subramanian M, Ahamed H, Mathew N, “STRAIN SCORE: A Novel Model for Prognostication of Short Term Outcomes in Stress Cardiomyopathy,” Euro Echo Imaging Congress (December 2017) –  Oral Presentation 

Subramanian M, Shanmugam A, Ahamed H, Mathew N, “Prognostic value of Echocardiography in Patients with Light Chain Cardiac Amyloidosis,” Euro Echo Imaging Congress (December 2017) – Moderated Poster Presentation 

Reddy C, Subramanian M, Matthew N, “Correlation between Bicuspid Aortic Valve Phenotype and Patterns of Aortopathy and Valvular Dysfunction,”  Euro Echo Imaging Congress (December 2017) –  Poster Presentation 

Subramanian M, Shanmugam A, Vijay K, Pavithran K, Ahamed H, Mathew N, “The Utility of a Novel Voltage Mass Ratio for Prognostication of Long Term Outcomes in Cardiac Amyloidosis,” –  Cardiological Society of India (December 2017) –  Oral Presentation 

Subramanian M, Mathew N, Ahamed H, “Regression of Cardiac Amyloidosis following autologous stem cell transplantation: The value of Global Longitudinal Strain,” – Echo India- (October 2017) –  Oral Presentation 

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