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Dr. Lalitha Biswas

Asst. Professor

Dr. Lalitha Biswas, Assistant Professor, Molecular Biology Diagnostics Group, ACNSMM.

Qualification: Ph.D
lalithabiswas@aims.amrita.edu

Bio

Dr. Lalitha Biswas joined as Assistant Professor at Amrita Institute of Medical Sciences in Jan 2010. She obtained her Ph.D from the University of Tuebingen, Germany. Her postdoctoral training was at University of Tuebingen, Germany and Purdue University, Indiana, USA. She was a member of the Graduate College Infection Biology (GKI-685), German Research Foundation and Sonder Forshungs Bereich (SFB). A couple of research projects on which she is currently working on is concentrated on molecular biology and Infection biology which is funded by DST and ICMR.

She adds to her achievements the author and co – author of nearly 11 publications in various reputed journals like journal of immunology, journal of Bacteriology etc. She qualified CSIR – NET in the year 2000. Apart from these she owned the DFG fellowship from 2002 – 2006 and also received the fellowship from German Sonder Forshungs Bereich for the year 2007 – 2009.

Currently, Dr. Biswas also heads the Molecular biology diagnostic laboratory, which provides diagnostic services under various categories such as histocompatability & immunogenetics, gene testing, pharmacogenomics, cancer genetics and molecular basis of infectious diseases.

 

Publications

Journal Article

Year : 2022

Describing the Clinical and Laboratory Features and HLA-B Pattern of Adult-Onset Idiopathic Autoimmune Uveitis at a Tertiary Hospital in South India: A Cross-Sectional Study

Authors : Niveditha Kartha, Dr. Lalitha Biswas, Jyothi Visalakshy, Sandeep Surendran, Salil Ganu, Kannisha Shah, C. B. Mithun, Vishal Marwaha, Gopale Pillai

Jyothi Visalakshy, Sandeep Surendran, Salil Ganu, Kannisha Shah, C. B. Mithun, Vishal Marwaha, Lalitha Biswas, Niveditha Kartha, Gopale Pillai, "Describing the Clinical and Laboratory Features and HLA-B Pattern of Adult-Onset Idiopathic Autoimmune Uveitis at a Tertiary Hospital in South India: A Cross-Sectional Study", The Scientific World Journal, vol. 2022, ArticleID 5032881, 9 pages, 2022.

Year : 2021

SARS-CoV-2 antibodies in healthcare workers in a large university hospital, Kerala, India

Authors : Dr. V. Anil Kumar, Dr. Lalitha Biswas, D. Sathyapalan, A. Ramachandran, K. Subhash, K.V. Beena

A. Kumar, D. Sathyapalan, A. Ramachandran, K. Subhash, L. Biswas, K.V. Beena "SARS-CoV-2 antibodies in healthcare workers in a large university hospital, Kerala, India", Clinical Microbiology and Infection, 2021

Year : 2021

Class II HLA (DRB1, & DQB1) alleles and IL7R (rs6897932) variants and the risk for Multiple Sclerosis in Kerala, India

Authors : Dr. Lalitha Biswas, Navia Vinoy; Neethu Sheeja; Suresh Kumar

Publisher : Multiple Sclerosis and Related Disorders, Volume 50, p.102848 (2021)

Navia Vinoy, Neethu Sheeja, Suresh Kumar, and Dr. Lalitha Biswas, “Class II HLA (DRB1, & DQB1) alleles and IL7R (rs6897932) variants and the risk for Multiple Sclerosis in Kerala, India.”, Multiple Sclerosis and Related Disorders, vol. 50, p. 102848, 2021.

Year : 2021

Dirofilarial adult worms can also dance.

Authors : Dr. V. Anil Kumar, Dr. Aswin Prabhakaran, Dr. Lalitha Biswas, Dr. Raja Biswas, Sanju Sherji; ; Arya Ramachandran; Mohan Abraham;

Publisher : Clinical Microbiology and Infection,

Dr. Anil Kumar V., Aswin Prabhakaran, Sanju Sherji, Dr. Lalitha Biswas, Arya Ramachandran, Mohan Abraham, and Dr. Raja Biswas, “Dirofilarial adult worms can also dance.”, Clinical Microbiology and Infection, vol. 27, pp. 1118-1119., 2021.

Year : 2021

Therapeutic applications of lysostaphin against Staphylococcus aureus

Authors : Dr. V. Anil Kumar, Dr. Lalitha Biswas, Dr. Raja Biswas, Jayakumar Jayashree

Publisher : Journal of Applied Microbiology,

J. Jayakumar, V.A. Kumar, L. Biswas,R. Biswas "Therapeutic applications of lysostaphin against Staphylococcus aureus" in Journal Appl Microbiol, 2021.

Year : 2021

Improving Diagnosis of Hepatitis C Virus Infection Using Hepatitis C Core Antigen Testing in a Resource-Poor Setting

Authors : Dr. V. Anil Kumar, Dr. Lalitha Biswas, Anjaly S. Nair, Dr. Shine Sadasivan, Dr. Raja Biswas, Ayswarya Kannan, Jessy Kurian, Parasmal Suresh

Publisher : pubmed.ncbi

Ayswarya Kannan, Lalitha Biswas, Anil Kumar, Jessy Kurian, Anjaly S Nair, Parasmal Suresh, Shine Sadasivan, Raja Biswas "Improving Diagnosis of Hepatitis C Virus Infection Using Hepatitis C Core Antigen Testing in a Resource-Poor Setting", Rev Soc Bras Med Trop, 2021

Year : 2021

Improving diagnosis of hepatitis C virus infection using hepatitis C core antigen testing in a resource-poor setting

Authors : Dr. V. Anil Kumar, Dr. Shine Sadasivan, Dr. Lalitha Biswas, Anjaly S. Nair, Dr. Raja Biswas

Ayswarya Kannan, Lalitha Biswas, Anil Kumar, Jessy Kurian, Anjaly S Nair, Parasmal Suresh, Shine Sadasivan, Raja Biswas "Improving Diagnosis of Hepatitis C Virus Infection Using Hepatitis C Core Antigen Testing in a Resource-Poor Setting",

Year : 2021

Comparison of Phenotypic MRSA Detection Methods with PCR for mecA Gene in the Background of Emergence of Oxacillin-Susceptible MRSA

Authors : Dr. V. Anil Kumar, Dr. Raja Biswas, Dr. Lalitha Biswas, Dr. Nandita Shashindran, Deepa Nair, Vivek Vinodh

Deepa Nair, Nandita Shashindran, Anil Kumar, Vivek Vinodh, Lalitha Biswas, and Raja Biswas "Comparison of Phenotypic MRSA Detection Methods with PCR for mecA Gene in the Background of Emergence of Oxacillin-Susceptible MRSA", Microbial Drug Resistance, 2021

Year : 2021

Eosinophilic Meningitis and Intraocular Infection Caused by Dirofilaria sp. Genotype Hongkong

Authors : Dr. V. Anil Kumar, Dr. Vinayan K. P., Dr. Lalitha Biswas, Dr. Sujithra H., Dr. Arun Grace Roy, Aruna S. Jyotsna, Parasmal Suresh

Aruna S. Jyotsna, Kollencheri Puthenveettil Vinayan, Lalitha Biswas, Sujithra Haridas, Arun G. Roy, Parasmal Suresh, and Anil Kumar "Eosinophilic Meningitis and Intraocular Infection Caused by Dirofilaria sp. Genotype Hongkong", Emerg Infect Dis Journal, 2021

Year : 2021

Protective efficacy of Alum adjuvanted Amidase protein vaccine against Staphylococcus aureus infection in multiple mouse models

Authors : Dr. V. Anil Kumar, Dr. Lalitha Biswas, Dr. Raja Biswas, Maneesha K. Suresh, Lalitha Biswas, Raja Biswas

Publisher : Journal of Applied Microbiology

Maneesha K. Suresh,Anil Kumar Vasudevan,Lalitha Biswas,Raja Biswas "Protective efficacy of Alum adjuvanted Amidase protein vaccine against Staphylococcus aureus infection in multiple mouse models" Journal of Applied Microbiology [Internet]. 2021

Year : 2021

Prevalence of high-risk HPV and its genotypes-Implications in the choice of prophylactic HPV vaccine.

Authors : Dr. Raja Biswas, Dr. Sarala Sreedhar, Dr. Lalitha Biswas, Alka Suresh; Parasmal Suresh; Anupama Rajanbabu

Publisher : J Med Virol

Alka Suresh, Parasmal Suresh, Dr. Raja Biswas, Anupama Rajanbabu, Sarala Sreedhar, and Dr. Lalitha Biswas, “Prevalence of high-risk HPV and its genotypes-Implications in the choice of prophylactic HPV vaccine.”, J Med Virol, vol. 93, no. 8, pp. 5188-5192, 2021.

Year : 2021

Universal screening for SARS-CoV-2 in pregnant women using a combination of antigen and RT-PCR testing.

Authors : Dr. V. Anil Kumar, Dr. Lalitha Biswas, Radhamany Kunjukutty; Ameena Thaha; Saranya Srikumar; Haritha Madhusoodanan; Sachin David;Dipu Sathyapalan

Publisher : Infezioni in Medicina

Dr. Anil Kumar V., Radhamany Kunjukutty, Ameena Thaha, Saranya Srikumar, Haritha Madhusoodanan, Sachin David, Dr. Lalitha Biswas, and Dipu Sathyapalan, “Universal screening for SARS-CoV-2 in pregnant women using a combination of antigen and RT-PCR testing.”, Infezioni in Medicina, vol. 29, no. 2, pp. 294-296, 2021.

Year : 2021

Candidatus Dirofilaria Hongkongensis Infections in Humans During 2005 to 2020, in Kerala, India.

Authors : Dr. V. Anil Kumar, Dr. Lalitha Biswas, Dr. Ajit Nambiar, Dr. Raja Biswas, Ani Sreedhar; Sarga Prabhat; Parasmal Suresh; Anisha Asokan;Rita Mary Tomy; Vivek Vinod;Bindu Lakshmanan

Publisher : American Journal of Tropical Medicine and Hygiene

Dr. Anil Kumar V., Ani Sreedhar, Dr. Lalitha Biswas, Sarga Prabhat, Parasmal Suresh, Asokan, A., Rita Mary Tomy, Vivek Vinod, Bindu Lakshmanan, Ajit Nambiar, and Dr. Raja Biswas, “Candidatus Dirofilaria Hongkongensis Infections in Humans During 2005 to 2020, in Kerala, India.”, American Journal of Tropical Medicine and Hygiene, vol. 104, pp. 2046-2049., 2021.

Year : 2021

Class II HLA (DRB1, & DQB1) alleles and IL7R (rs6897932) variants and the risk for Multiple Sclerosis in Kerala, India.

Authors : Dr. Lalitha Biswas, Navia Vinoy;Neethu Sheeja;Suresh Kumar

Publisher : Multiple Sclerosis and Related Disorders

Navia Vinoy, Neethu Sheeja, Suresh Kumar, and Dr. Lalitha Biswas, “Class II HLA (DRB1, & DQB1) alleles and IL7R (rs6897932) variants and the risk for Multiple Sclerosis in Kerala, India.”, Multiple Sclerosis and Related Disorders, vol. 50, p. 102848, 2021.

Year : 2021

Comparison of Phenotypic MRSA Detection Methods with PCR for Gene in the Background of Emergence of Oxacillin-Susceptible MRSA.

Authors : Dr. Nandita Shashindran, Dr. Lalitha Biswas, Dr. Raja Biswas, Deepa Nair; Anil kumar; Vivek Vinodh

Publisher : Microbial Drug Resistance

Deepa Nair, Nandita Shashindran, Anil kumar, Vivek Vinodh, Dr. Lalitha Biswas, and Dr. Raja Biswas, “Comparison of Phenotypic MRSA Detection Methods with PCR for Gene in the Background of Emergence of Oxacillin-Susceptible MRSA.”, Microbial Drug Resistance, vol. 27, no. 9, pp. 1190-1194, 2021.

Year : 2021

Protective efficacy of Alum adjuvanted Amidase protein vaccine against Staphylococcus aureus infection in multiple mouse models.

Authors : Dr. Lalitha Biswas, Dr. Raja Biswas, Suresh, M.K.; Vasudevan, A.K

Publisher : Journal of Applied Microbiology

M. K. Suresh, Vasudevan, A. K., Dr. Lalitha Biswas, and Dr. Raja Biswas, “Protective efficacy of Alum adjuvanted Amidase protein vaccine against Staphylococcus aureus infection in multiple mouse models.”, Journal of Applied Microbiology (Article in Press), 2021.

Year : 2021

Improving Diagnosis of Hepatitis C Virus Infection Using Hepatitis C Core Antigen Testing in a Resource-Poor Setting.

Authors : Dr. Raja Biswas, Dr. Lalitha Biswas, Ayswarya Kannan; Anil Kumar; Jessy Kurian; Anjaly S. Nair; Parasmal Suresh; Shine Sadasivan;

Publisher : Rev Soc Bras Med Trop

Ayswarya Kannan, Dr. Lalitha Biswas, Anil Kumar, Jessy Kurian, Anjaly S. Nair, Parasmal Suresh, Shine Sadasivan, and Dr. Raja Biswas, “Improving Diagnosis of Hepatitis C Virus Infection Using Hepatitis C Core Antigen Testing in a Resource-Poor Setting.”, Rev Soc Bras Med Trop, vol. 54, p. e02532020, 2021.

Year : 2020

BCG Infection due to MPT64 – Negative Strain: A Diagnostic Challenge

Authors : Dr. V. Anil Kumar, Dr. Raja Biswas, Dr. Vinitha Prasad, Dr. Lalitha Biswas, Parasmal Suresh, Sadia Khan

Parasmal Suresh, Lalitha Biswas, Vinitha Prasad, Anil Kumar, Suchitra Sivadas, Sadia Khan, and Raja Biswas "BCG Infection due to MPT64-Negative Strain: A Diagnostic Challenge", American Journal of Tropical Medicine Hygiene, 2021

Year : 2020

Mutation Profile of JAK2, EPOR and CALR Genes in Polycythemia Patients

Authors : Dr. Lalitha Biswas, Anbinselvam. A., Sidharthan, N, Vidyadharan, G, Kurian, J

Publisher : Blood Cells, Molecules, and Diseases

A. A., Sidharthan, N., Vidyadharan, G., Kurian, J., and Dr. Lalitha Biswas, “Mutation Profile of JAK2, EPOR and CALR Genes in Polycythemia Patients”, Blood Cells, Molecules, and Diseases, vol. 82, p. 102414, 2020.

Year : 2017

Lack of Association of B-type Raf Kinase V600E Mutation with High-risk Tumor Features and Adverse Outcome in Conventional and Follicular Variants of Papillary Thyroid Carcinoma

Authors : Dr. Pradeep Jacob, Dr. Riju R. Menon, Dr. Lalitha Biswas, Nair CG; Babu M;Revathy AK; Nair K

Publisher : Indian Journal of Endocrinol Metab

Dr. Lalitha Biswas, CG, N., M, B., Pradeep Jacob, Riju R. Menon, AK, R., and K, N., “Lack of Association of B-type Raf Kinase V600E Mutation with High-risk Tumor Features and Adverse Outcome in Conventional and Follicular Variants of Papillary Thyroid Carcinoma”, Indian Journal of Endocrinol Metab, vol. 21, no. 2, pp. 329-333, 2017.

Year : 2017

Impact of Cell Wall Peptidoglycan O-acetylation on the Pathogenesis of Staphylococcus Aureus in Septic Arthritis

Authors : Dr. Raja Biswas, Dr. Lalitha Biswas, Dr. Sahadev Shankarappa, Baranwal, Gaurav; Mohammad, Majd; Jarneborn, Anders; Reddy, Bommana Raghunath; Golla, Archana; Chakravarty, Sumana; Götz, Friedrich; Jin, Tao;

Publisher : Int J Med Microbiol

G. Baranwal, Mohammad, M., Jarneborn, A., Reddy, B. Raghunath, Golla, A., Chakravarty, S., Biswas, L., Götz, F., Dr. Sahadev Shankarappa, Jin, T., and Dr. Raja Biswas, “Impact of Cell Wall Peptidoglycan O-acetylation on the Pathogenesis of Staphylococcus Aureus in Septic Arthritis”, Int J Med Microbiol, vol. 307, no. 7, pp. 388-397, 2017.

Year : 2017

First Two Bilateral Hand Transplantations in India (Part 4): Immediate Post-operative Care, Immunosuppression Protocol and Monitoring

Authors : Dr. Lalitha Biswas, Iyer S; Sharma M; Kishore P; Mathew J; Janarthanan R; Reddy R; Wakure A; Vijayaraghavan S,; Chetan Mali SM; Varma V; Chaudhari A; Dhake S; Omkumar A; Kurian G; Nair R; Mathew A; Paul Z; Eapen M

Publisher : Indian J Plast Surg

Dr. Lalitha Biswas, S, I., M, S., P, K., J, M., R, J., R, R., A, W., ,, SM, C. Mali, V, V., A, C., S, D., A, O., G, K., R, N., A, M., Z, P., and M, E., “First Two Bilateral Hand Transplantations in India (Part 4): Immediate Post-operative Care, Immunosuppression Protocol and Monitoring”, Indian J Plast Surg, vol. 50, no. 2, pp. 168-172, 2017.

Year : 2017

Epidermal Growth Factor Receptor (EGFR) Structure-based Bioactive Pharmacophore Models for Identifying Next-generation Inhibitors Against Clinically relevant EGFR Mutations

Authors : Dr. Gopi Mohan C., Dr. Lalitha Biswas, Panicker, Pooja S.; Melge, Anu R.; Keechilat, Pavithran;

Publisher : Chemical Biology Drug Design

P. S. Panicker, Melge, A. R., Dr. Lalitha Biswas, Keechilat, P., and Dr. Gopi Mohan C., “Epidermal Growth Factor Receptor (EGFR) Structure-based Bioactive Pharmacophore Models for Identifying Next-generation Inhibitors Against Clinically relevant EGFR Mutations”, Chemical Biology & Drug Design, vol. 90, pp. 629-636, 2017.

Year : 2016

Detection of Occult Hepatitis B and Window Period Infection Among Blood Donors by Individual donation Nucleic Acid Testing in a Tertiary Care Center in South India

Authors : Dr. Prem Kumar Nair, Dr. Lalitha Biswas, Keechilot, C.S.; Shenoy, V.; Kumar, A.; Vijayrajratnam, S; Dinesh, K.;

Publisher : Pathogens and Global Health, Taylor and Francis.

C. S. Keechilot, Shenoy, V., A. Kumar, Dr. Lalitha Biswas, Vijayrajratnam, S., Dinesh, K., and Dr. Prem Kumar Nair, “Detection of Occult Hepatitis B and Window Period Infection Among Blood Donors by Individual donation Nucleic Acid Testing in a Tertiary Care Center in South India”, Pathogens and Global Health, pp. 1-5, 2016.

Year : 2015

Amidase, a Cell Wall Hydrolase, Elicits Protective Immunity Against Staphylococcus Aureus and S. Epidermidis

Authors : Dr. Raja Biswas, Dr. Lalitha Biswas, Nair, N.; Vinod, V.; Suresh, M.K.; Vijayrajratnam, S.; Peethambaran, R.; Vasudevan, A.K.;

Publisher : International Journal of Biological Macromolecules, Elsevier

N. Nair, Vinod, V., Suresh, M. K., Vijayrajratnam, S., Dr. Lalitha Biswas, Peethambaran, R., Vasudevan, A. K., and Dr. Raja Biswas, “Amidase, a Cell Wall Hydrolase, Elicits Protective Immunity Against Staphylococcus Aureus and S. Epidermidis”, International Journal of Biological Macromolecules, vol. 77, pp. 314-321, 2015.

Year : 2014

Staphylococcus aureus in polymicrobial infections: impact on pathogenesis

Authors : Dr. Raja Biswas, Dr. Lalitha Biswas, Nair, Nisha; Götz, Friedrich.

Publisher : Infection and Immunity, American Society for Microbiology,

N. Nair, Dr. Raja Biswas, Götz, F., and Biswas, L., “Staphylococcus aureus in polymicrobial infections: impact on pathogenesis”, Infection and Immunity, p. IAI–00059, 2014.

Year : 2014

Autochthonous Blastomycosis of the Adrenal: First Case Report from Asia

Authors : Dr. Lalitha Biswas, Anil Kumar, Sreehari, S., Velayudhan, K.,, Babu, R., Ahmed, S., Sharma, N., Kurupath, V. P., Jojo, A., Dinesh, K. R., Karim, S., and Biswas, R.

Publisher : The American Journal of Tropical Medicine and Hygiene

Anil Kumar, Sreehari, S., Velayudhan, K., Dr. Lalitha Biswas, Babu, R., Ahmed, S., Sharma, N., Kurupath, V. P., Jojo, A., Dinesh, K. R., Karim, S., and Biswas, R., “Autochthonous Blastomycosis of the Adrenal: First Case Report from Asia”, The American Journal of Tropical Medicine and Hygiene, vol. 90, 2014.

Year : 2013

Innate immune recognition of microbial cell wall components and microbial strategies to evade such recognitions

Authors : Dr. Raja Biswas, Dr. V. Anil Kumar, Dr. Lalitha Biswas, Sukhithasri, V.a; Nisha, N.a;

Publisher : Microbiological Research

Va Sukhithasri, Nisha, Na, Dr. Lalitha Biswas, Kumar, VbAnil, and Dr. Raja Biswas, “Innate immune recognition of microbial cell wall components and microbial strategies to evade such recognitions”, Microbiological Research, vol. 168, pp. 396-406, 2013.

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