Year : 2024
Chalcones with N-Methylpiperazine Moiety: Synthesis, Monoamine Oxidase Inhibition, Neuroprotective Effect and Computer Simulation Study
Cite this Research Publication : Jayan J, Trisciuzzi D, Benny F, Kumar S, Gambacorta N, Catto M, Abdelgawad MA, Ghoneim MM, Al‐Serwi RH, Gahtori P, Zachariah SM. Chalcones with N‐Methylpiperazine Moiety: Synthesis, Monoamine Oxidase Inhibition, Neuroprotective Effect and Computer Simulation Study. Chemistry Select, 2024.
Year : 2023
A Concise Review of the Recent Structural Explorations of Chromones as MAO-B Inhibitors: Update from 2017 to 2023
Cite this Research Publication :
Reshma Susan Ipe , Sunil Kumar, Feba Benny, Jayalakshmi Jayan, Amritha Manoharan , Sachitra Thazhathuveedu Sudevan, Ginson George Prashant Gahtori,Hoon Kim Bijo Mathew, 2023. Pharmaceuticals 2023.
Year : 2023
Exploiting butyrylcholinesterase inhibitors through a combined 3-D pharmacophore modeling, QSAR, molecular docking, and molecular dynamics investigation
Cite this Research Publication : Kumar S, Manoharan A, Jayan J, Abdelgawad MA, Mahdi WA, Alshehri S, Ghoneim MM, Pappachen LK, Zachariah SM, Aneesh TP, Mathew B., Exploiting butyrylcholinesterase inhibitors through a combined 3-D pharmacophore modeling, QSAR, molecular docking, and molecular dynamics investigation, RSC Adv. 2023 Mar 23;13(14):9513-9529. doi:10.1039/d3ra00526g. Erratum in: RSC Adv, 2023.
Year : 2023
Review of β-carboline and its derivatives as selective MAO-A inhibitors
Cite this Research Publication : Benny F, Kumar S, Jayan J, Abdelgawad MA, Ghoneim MM, Kumar A, Manoharan A, Susan R, Sudevan ST, Mathew B., Review of β‐carboline and its derivatives as selective MAO‐A inhibitors, Archiv der Pharmazie, 2023.
Year : 2023
Flavonoid and Chalcone Scaffolds as Inhibitors of BACE1: Recent Updates
Cite this Research Publication :
Narayanan AP, Jayan J, Sudevan ST, Dhyani A, Zachariah SM, Mathew B. Flavonoid and Chalcone Scaffolds as Inhibitors of BACE1: Recent Updates. Comb Chem High Throughput Screen, 2023.
Year : 2023
A structure-based approach to explore novel COX-2 inhibitors using pharmacophore modelling, 3D-QSAR analysis, virtual screening and dynamics simulation study
Cite this Research Publication :
Krishnendu PR, Benny S, Kumar S, Jayan J, Bhaskar V, Pappachen LK, Aneesh TP, Abdelgawad MA, Ghoneim MM, Nicolotti O, Zachariah SM, A structure-based approach to explore novel COX-2 inhibitors using pharmacophore modelling, 3D-QSAR analysis, virtual screening and dynamics simulation study, Journal of Molecular Structure. 2023.
Publisher : Elsevier
Year : 2023
“Click Chemistry”: An Emerging Tool for Developing a New Class of Structural Motifs against Various Neurodegenerative Disorders
Cite this Research Publication : Manoharan, A.,Jayalakshmi J, Rangarajan, T. M., Bose, K., Benny, F., Ipe, R. S., Kumar, S., Kukreti, N., Abdelgawad, M. A., Ghoneim, M. M., Kim, H., & Mathew, B., "Click Chemistry": An Emerging Tool for Developing a New Class of Structural Motifs against Various Neurodegenerative Disorders. ACS omega,2023.
Year : 2023
Discerning of isatin-based monoamine oxidase (MAO) inhibitors for neurodegenerative disorders by exploiting 2D, 3D-QSAR modelling and molecular dynamics simulation
Cite this Research Publication : Kumar S, Jayalakshmi J, Manoharan A, Benny F, Abdelgawad MA, Ghoneim MM, El-Sherbiny M, Thazhathuveedu Sudevan S, Aneesh TP, Mathew B. Discerning of isatin-based monoamine oxidase (MAO) inhibitors for neurodegenerative disorders by exploiting 2D, 3D-QSAR modelling and molecular dynamics simulation, Journal of Biomolecular Structure and Dynamics,2024 .
Year : 2023
Piperidine: A Versatile Heterocyclic Ring for Developing Monoamine Oxidase Inhibitors
Cite this Research Publication : Jayalakshmi J, Chandran N, Thekkantavida AC, Abdelgawad MA, Ghoneim MM, Shaker ME, Uniyal P, Benny F, Zachariah SM, Kumar S, Kim H, Mathew B, Piperidine: A Versatile Heterocyclic Ring for Developing Monoamine Oxidase Inhibitors, ACS Omega, 2023.
Year : 2023
Development of a New Class of Monoamine Oxidase-B Inhibitors by Fine-Tuning the Halogens on the Acylhydrazones
Cite this Research Publication :
Jayalakshmi J, Lee J, Kumar S, Manoharan A, Narayanan AP, Jauhari R, Abdelgawad MA, Ghoneim MM, Ebrahim HA, Mary Zachariah S, Kim H, Mathew B. Development of a New Class of Monoamine Oxidase-B Inhibitors by Fine-Tuning the Halogens on the Acylhydrazones, ACS Omega. 2023.
Year : 2022
Effects of radiation exposure on brain health: a state of the art and new challenges
Cite this Research Publication : Jayan J, Roshi H, Ashraf FF, Nair PG, Vijayakumar A, Nair AS, Pappachen LK, Abdelgawad MA, Parambi DG, Aleya L, Mathew B., Effects of radiation exposure on brain health: a state of the art and new challenges.,Environmental Science and Pollution Research, 2022.
Publisher : Springer